Phytopharmaceuticals. Группа авторов

Rosehip oil FT-MIR PLS-DA [185] Discrimination of different parts of a plants Commifora wightii GC–MS NMR PCA PLS-DA [189]

2.5 Conclusions

      The characterization of natural ingredients including biocompounds eco-friendly extracted from undervaluated non-traditional sources will be an attractive topic in medicinal, food and even in cosmetic industries.

      Many nontraditional unexploited sources of bioactive compounds, such as native botanicals, by products and wastes from agroindustrial production have been presented. However, some aspects should be overcome before they could be effectively employed for nutraceutical, pharmaceutical or cosmetic applications, which comprise:

      1 a) The implementation of adequate extraction techniques, which not only reduce time and save operational costs, but also allow to assess complete bioactive release from the vegetable matrices. Research has to be done also for the transference of these technologies from laboratory to industrial scale.

      2 b) The standardization of analytical procedures for evaluating the pursued functions, with adequate interlaboratory comparisons. At this point, it is important to clearly indicate the expression of bioactives concentrations. We suggest to do that on dry basis of the original material.

      3 c) The availability of conservation techniques for bioactives and adequate coating materials, which are important strategies to increase the possibilities of the industrial application of natural components, allowing the modification of release kinetics.

      4 d) The use of multivariate methods, which allow interpreting data represented in the multiple variables that include analytical results and samples composition and conditions.

      Other important issues for nutraceuticals or pharmaceuticals development, are the definition of effective dose or maximum daily allowance for a given bioactive and the effective absorption and distribution of the bioactives in the body, which requires the performance of digestibility tests.

Acknowledgements

      The authors acknowledge Red Temática CYTED, Programa Iberoamericano de Ciencia y Tecnología para el Desarrollo 415RT0495 (LACFUN) and to PDTS CIN_CONICET 0196 Project.

Abbreviations

CYTED	Iberoamerican Program of Science and Technology for Development
GG	guar gum
ECG	Espina corona seed gum
VG	vinal seed gum
PAEG	Prosopis alba exudate gum
ANMAT	Argentine National Administration of Drugs, Food and Medical Technology
OE	Oleuropein
OLE	olive leaves extracts
LPH	lactase florocin hydrolase
HT	hydroxytyrosol
UAE	ultrasound assited extraction
EAE	enzymes assisted extraction
MAE	microwaves assisted extraction
DMAE	Dynamic microwave assisted extraction
EUMAE	Enzyme-based ultrasonic/microwave-assisted extraction
CDs	cyclodextrins
DPPH	diphenyl picryl hydrazyl
ABTS	2,2-azinobis 3-ethyl-benzothiazoline-6-sulfonic
TP	total phenols
AA	antioxidant activity
K	Kardinal
GG	Gran Gala
KR	King’s Ransom
CC	Cristóbal Colón
FRAP	ferrric reducing
CUPRAC	cupric reducing antioxidant capacity
ORAC	oxygen radical absorbance capacity
TLC	Thin layer chromatography
RR	Rapistrum rugosum
SA	Sinapis arvensis
HRMS	high resolution mass spectroscopy
BSA	bovine serum albumin
PBS	phosphate buffered saline solution
AGEs	advanced glycosilation end products
CEL	Nε-carboxyethyllysine
CML	Nε-carboxymethyl-lysine
HPLC	hight performance liquid chromatography (DAD: is with diode array detection)
FPI	Flaxseed protein
FG	flaxseed gum
GE	Gelatine
SA	sodium alginate
GDL	glucono-β-lactone
MVA	Multivariate analysis
PCA	principal component analysis
Скачать книгу В начало < 24 25 26 27 28 29 30 31 32 33 > В конец