Nanobiotechnology in Diagnosis, Drug Delivery and Treatment. Группа авторов

Department of Pharmaceutics, Institute of Pharmaceutical Education and Research Borgaon (Meghe) Wardha, Maharashtra India

      Shagufta Khan Department of Pharmaceutics, Institute of Pharmaceutical Education and Research Borgaon (Meghe) Wardha Maharashtra India

      Dipak Maity Department of Chemical Engineering Institute of Chemical Technology Mumbai, Indian Oil Campus, IIT KGP Extension Centre, Bhubaneswar, Odisha India

      Atul Sudame Department of Mechanical Engineering Shiv Nadar University Greater Noida, Uttar Pradesh India

Ganeshlenin Kandasamy Department of Biomedical Engineering Vel Tech Rangarajan Dr. Sagunthala R&D Institute of Science and Technology Chennai, Tamil Nadu India Yasser Shahzad Department of Pharmacy COMSATS University Islamabad, Lahore Pakistan

      Abid Mehmood Yousaf Department of Pharmacy COMSATS University Islamabad, Lahore Pakistan

      Talib Hussain Department of Pharmacy COMSATS University Islamabad, Lahore Lahore Pakistan

      Syed A.A. Rizvi School of Pharmacy Hampton University Virginia USA

      Parinaz Nezhad‐Mokhtari Department of Medical Nanotechnology Faculty of Advanced Medical Sciences University of Medical Sciences Tabriz Iran

      Fatemeh Salahpour‐Anarjan Department of Medical Nanotechnology Faculty of Advanced Medical Sciences University of Medical Sciences Tabriz Iran

      Armin Rezanezhad Faculty of Mechanical Engineering, Department of Materials Science and Engineering University of Tabriz Tabriz Iran

      Abolfazl Akbarzadeh Department of Medical Nanotechnology Faculty of Advanced Medical Sciences and Stem Cell Research Center University of Tabriz Tabriz Iran and Stem Cell Research University of Tabriz

      Divya Koilparambil School of Biosciences Mahatma Gandhi University Kottayam, Kerala India

      Sherin Varghese School of Biosciences Mahatma Gandhi University Kottayam, Kerala India

      Jisha Manakulam Shaikmoideen School of Biosciences Mahatma Gandhi University Kottayam, Kerala India

      Priti Paralikar Nanobiotechnology Laboratory, Department of Biotechnology SGB Amravati University Amravati, Maharashtra India

      Erasmo Gámez‐Espinosa Center for Research and Development in Painting Technology National University of La Plata La Plata Buenos Aires, Argentina

      Leyanet Barberia‐Roque Center for Research and Development in Painting Technology National University of La Plata La Plata Buenos Aires, Argentina

Natalia Bellotti Center for Research and Development in Painting Technology National University of La Plata La Plata Buenos Aires, Argentina and Faculty of Natural Sciences and Museum National University of La Plata La Plata Argentina Jacqueline Teixeira da Silva Laboratory of Nanobiotechnology, Institute of Tropical Pathology and Public Health Federal University of Goiás Goiânia Brazil

      Andre Correa Amaral Laboratory of Nanobiotechnology, Institute of Tropical Pathology and Public Health Federal University of Goiás Goiânia Brazil

      Smitha Vijayan School of Bioscience Mahatma Gandhi University Kottayam, Kerala India

      Mohammad Imani Novel Drug Delivery Systems Department Iran Polymer and Petrochemical Institute Tehran Iran

      Azam Dehghan Novel Drug Delivery Systems Department Iran Polymer and Petrochemical Institute Tehran Iran

      Thais Francine Ribeiro Alves Laboratory of Biomaterials and Nanotechnology, LaBNUS University of Sorocaba Sorocaba Brazil

      Fernando Batain Laboratory of Biomaterials and Nanotechnology, LaBNUS University of Sorocaba Sorocaba Brazil

      Cecília Torqueti de Barros Laboratory of Biomaterials and Nanotechnology, LaBNUS University of Sorocaba Sorocaba Brazil

      Kessie Marie Moura Crescencio Laboratory of Biomaterials and Nanotechnology, LaBNUS University of Sorocaba Sorocaba Brazil

      Venâncio Alves do Amaral Laboratory of Biomaterials and Nanotechnology, LaBNUS University of Sorocaba Sorocaba Brazil

      Mariana Silveira de Alcântara Chaud Department of Cardiology, Municipal Clinics Hospital José Alencar São Bernardo do Campo Brazil

      Décio Luís Portella Laboratory of Biomaterials and Nanotechnology, LaBNUS University of Sorocaba Sorocaba Brazil and Department of Surgery and Plastic Surgery Pontifical Catholic University of São Paulo Sorocaba Brazil

      Marco Vinícius Chaud Laboratory of Biomaterials and Nanotechnology, LaBNUS University of Sorocaba Sorocaba Brazil

      Indarchand Gupta Department of Biotechnology Government Institute of Science Nipat‐Niranjan Nagar Aurangabad, Maharashtra India and Nanobiotechnology Laboratory, Department of Biotechnology SGB Amravati University Amravati, Maharashtra India

Preface

      In the last two decades, nanotechnology has revolutionized different areas of research as well as life. It has demonstrated its promising power to resolve the majority of medical problems like infectious diseases, cancer, genetic disorders, neurodegenerative diseases, etc. Nanomedicine, which refers to highly specific medical intervention at the scales of 100 nm or less for diagnosis, prevention, and treatment of diseases, is one of the most promising areas of nanotechnology.

      The major face of nanomedicine is “drug delivery,” which is considered as one of the most promising functions of nanotechnology and can maneuver molecules and supramolecular structures to create devices with programmed functions. The current drug delivery systems are distributed into the nano‐ and microscale systems which mainly involve the use of nanoparticles, liposomes, polymeric micelles (nanovehicles), dendrimers, nanocrystals, microchips, microtherapeutic systems, aptamer‐incorporated nanoparticles, and novel microparticles of size 100 nm. These technologies will be expanded in the future to establish efficient nano/microdrug delivery systems in a manner which will provide future necessities of medicine in terms of diagnosis and treatment of infectious diseases, with special focus on those microbes which are emerging as drug‐resistant.

In this book, there are 17 chapters that are broadly focused on the recent advances in nano‐based drug delivery systems, diagnosis, and the role of various nanomaterials in the management of infectious diseases and non‐infectious disorders such as cancers and other malignancies and their role in future medicine. Chapter 1 is an introductory chapter that presents the role of nanotechnology as revolutionary science as far as drug delivery, diagnosis, and treatment of diseases are concerned. Chapter 2 focuses on the role of selenium nanocomposites in diagnosis, drug delivery, and treatment of diseases like cancer, Alzheimer's disease, diabetes, and many others. Chapter 3 includes the application of a variety of nanomaterials in the diagnosis and management of gastrointestinal tract disorders. Chapter 4 explains the concept of nanotheranostics in detail and its role in effective monitoring of drug response, targeted drug delivery, enhanced drug accumulation in the target tissues, sustained as well as the triggered release of drugs, reduction in adverse effects, etc. Chapter 5 discusses the application of aptamer‐incorporated nanoparticle systems for drug delivery, which is considered as one of the most compelling medicinal platforms of nanotechnology. The aptamer‐incorporated nanoparticle systems are reported