Immunophenotyping for Haematologists. Barbara J. Bain

      

      Table of Contents

      1  Cover

      2  Title Page

      3  Copyright Page

      4  Preface

      5  Acknowledgement

      6  Abbreviations Used in the Book

      7  Part 1: Purpose and Principles of Immunophenotyping Flow Cytometric Immunophenotyping Immunohistochemistry Interpretation and Limitations of Flow Cytometric Immunophenotyping Problems and Pitfalls References Bibliography

      8  Part 2: Immunophenotyping for Haematologists A Compendium of Antibodies and Patterns of Expression of Equivalent Antigens in Normal and Neoplastic Cells Abbreviations Antibodies with CD numbers Antibodies without CD numbers Bibliography Websites

      9  Part 3: Immunophenotyping in the Diagnosis and Monitoring of Haematological Neoplasms and Related Conditions with Tables and Figures for Quick Reference Abbreviations Normal Peripheral Blood and Bone Marrow Cells, Lineage and Stem Cell Markers Acute Myeloid Leukaemia Acute Lymphoblastic Leukaemia, Mixed Phenotype Acute Leukaemia and Undifferentiated Acute Leukaemia Myelodysplastic Syndromes and Myelodysplastic/Myeloproliferative Neoplasms Myeloproliferative Neoplasms Systemic Mastocytosis Blastic Plasmacytoid Dendritic Cell Neoplasm Langerhans Cell Histiocytosis and Erdheim–Chester Disease Histiocytic Sarcoma Mature B‐lineage Neoplasms Plasma Cell Neoplasms Hodgkin Lymphoma Mature T‐lineage and NK‐lineage Neoplasms Minimal Residual Disease Paroxysmal Nocturnal Haemoglobinuria Conclusion References Bibliography Websites

      10  Part 4: Test Yourself Abbreviations Short Answer Questions (Single Best Answer) Extended Matching Questions FRCPath‐Type Questions Answers to SAQs Answers to EMQs Answers to FRCPath‐Type Questions References Further Reading

      11  Index

      12  End User License Agreement

      List of Tables

      1 Part 1Table 1.1 Commonly used fluorochromes.Table 1.2 Role of flow cytometric immunophenotyping.

      2 Part 3Table 3.1 Lineage and stem cell markers.Table 3.2 Immunophenotyping of acute myeloid leukaemia and blastic plasmacyto...Table 3.3 Immunophenotyping of normal mature T and B cells and in acute lymph...Table 3.4 Maturation stages of B‐lineage acute lymphoblastic leukaemia.Table 3.5 Typical immunophenotypic characteristics of common ALL cells compar...Table 3.6 Maturation stages of T‐lineage acute lymphoblastic leukaemia.Table 3.7 A scoring system for the identification of early T‐cell precursor a...Table 3.8 Markers that are required for the definition of mixed phenotype acu...Table 3.9 Markers that have been applied in the diagnosis of myelodysplastic ...Table 3.10 Characteristic immunophenotype of chronic B‐cell leukaemias and B‐...Table 3.11 A comparison of the typical immunophenotype of normal plasma cells...Table 3.12 A comparison of the typical immunophenotype of neoplastic cells in...Table 3.13 Characteristic immunophenotype of mature T‐cell and NK‐cell neopla...Table 3.14 Antibodies that can be used in panels for monitoring minimal resid...Table 3.15 Markers that can be used in the flow cytometric diagnosis of parox...

      List of Illustrations

      1 Part 1Figure 1.1 Diagrammatic representation of the principles of flow cytometric ...Figure 1.2 Delineation of peripheral blood leucocyte populations using forwa...Figure 1.3 Delineation of