Живи долго! Научный подход к долгой молодости и здоровью. Майкл Грегер

      176

      Grahame Hardie D. Regulation of AMP-activated protein kinase by natural and synthetic activators. Acta Pharm Sin B. 2016;6(1):1–19. https://pubmed.ncbi.nlm.nih.gov/26904394/

      177

      Wu Y, Song P, Zhang W, et al. Activation of AMPKa2 in adipocytes is essential for nicotine-induced insulin resistance in vivo. Nat Med. 2015;21(4):373–82. https://pubmed.ncbi.nlm.nih.gov/25799226/

      178

      Martínez de Morentin PB, Whittle AJ, Fernø J, et al. Nicotine induces negative energy balance through hypothalamic AMP-activated protein kinase. Diabetes. 2012;61(4):807–17. https://pubmed.ncbi.nlm.nih.gov/22315316/

      179

      Ferguson SG, Shiffman S, Rohay JM, Gitchell JG, Garvey AJ. Effect of compliance with nicotine gum dosing on weight gained during a quit attempt. Addiction. 2011;106(3):651–6. https://pubmed.ncbi.nlm.nih.gov/21182551/

      180

      Novak CM, Gavini CK. Smokeless weight loss. Diabetes. 2012;61(4):776–7. https://pubmed.ncbi.nlm.nih.gov/22442297/

      181

      Hadi A, Arab A, Ghaedi E, Rafie N, Miraghajani M, Kafeshani M. Barberry (Berberis vulgaris L.) is a safe approach for management of lipid parameters: a systematic review and meta-analysis of randomized controlled trials. Complement Ther Med. 2019;43:117–24. https://pubmed.ncbi.nlm.nih.gov/30935518/

      182

      Fouladi RF. Aqueous extract of dried fruit of Berberis vulgaris L. in acne vulgaris, a clinical trial. J Diet Suppl. 2012;9(4):253–61. https://pubmed.ncbi.nlm.nih.gov/23038982/

      183

      Emamat H, Asadian S, Zahedmehr A, Ghanavati M, Nasrollahzadeh J. The effect of barberry (Berberis vulgaris) consumption on flow-mediated dilation and inflammatory biomarkers in patients with hypertension: a randomized controlled trial [published online ahead of print, 2020 Dec 22]. Phytother Res. 2020;10.1002/ptr.7000. https://pubmed.ncbi.nlm.nih.gov/33350540/

      184

      Shidfar F, Ebrahimi SS, Hosseini S, Heydari I, Shidfar S, Hajhassani G. The effects of Berberis vulgaris fruit extract on serum lipoproteins, apoB, apoA-I, homocysteine, glycemic control and total antioxidant capacity in type 2 diabetic patients. Iran J Pharm Res. 2012;11(2):643–52. https://pubmed.ncbi.nlm.nih.gov/24250489/

      185

      McCarty MF. AMPK activation – protean potential for boosting healthspan. Age (Dordr). 2014;36(2):641–63. https://pubmed.ncbi.nlm.nih.gov/24248330/

      186

      Shidfar F, Ebrahimi SS, Hosseini S, Heydari I, Shidfar S, Hajhassani G. The effects of Berberis vulgaris fruit extract on serum lipoproteins, apoB, apoA-I, homocysteine, glycemic control and total antioxidant capacity in type 2 diabetic patients. Iran J Pharm Res. 2012;11(2):643–52. https://pubmed.ncbi.nlm.nih.gov/24250489/

      187

      Funk RS, Singh RK, Winefield RD, et al. Variability in potency among commercial preparations of berberine. J Diet Suppl. 2018;15(3):343–51. https://pubmed.ncbi.nlm.nih.gov/28792254/

      188

      Arayne MS, Sultana N, Bahadur SS. The berberis story: Berberis vulgaris in therapeutics. Pak J Pharm Sci. 2007;20(1):83–92. https://pubmed.ncbi.nlm.nih.gov/17337435/

      189

      Grahame Hardie D. Regulation of AMP-activated protein kinase by natural and synthetic activators. Acta Pharm Sin B. 2016;6(1):1–19. https://pubmed.ncbi.nlm.nih.gov/26904394/

      190

      Tavakoli-Rouzbehani OM, Maleki V, Shadnoush M, Taheri E, Alizadeh M. A comprehensive insight into potential roles of Nigella sativa on diseases by targeting AMP-activated protein kinase: a review. Daru. 2020;28(2):779–87. https://pubmed.ncbi.nlm.nih.gov/33140312/

      191

      Mousavi SM, Sheikhi A, Varkaneh HK, Zarezadeh M, Rahmani J, Milajerdi A. Effect of Nigella sativa supplementation on obesity indices: a systematic review and meta-analysis of randomized controlled trials. Complement Ther Med. 2018;38:48–57. https://pubmed.ncbi.nlm.nih.gov/29857879/

      192

      Sahebkar A, Beccuti G, Simental-Mendía LE, Nobili V, Bo S. Nigella sativa (black seed) effects on plasma lipid concentrations in humans: a systematic review and meta-analysis of randomized placebo-controlled trials. Pharmacol Res. 2016;106:37–50. https://pubmed.ncbi.nlm.nih.gov/26875640/

      193

      Sahebkar A, Soranna D, Liu X, et al. A systematic review and meta-analysis of randomized controlled trials investigating the effects of supplementation with Nigella sativa (black seed) on blood pressure. J Hypertens. 2016;34(11):2127–35. https://pubmed.ncbi.nlm.nih.gov/27512971/

      194

      Daryabeygi-Khotbehsara R, Golzarand M, Ghaffari MP, Djafarian K. Nigella sativa improves glucose homeostasis and serum lipids in type 2 diabetes: a systematic review and meta-analysis. Complement Ther Med. 2017;35:6–13. https://pubmed.ncbi.nlm.nih.gov/29154069/

      195

      Agricultural Research Service, United States Department of Agriculture. Sweet sunnah, whole black seeds nigella sativa. FoodData Central. https://fdc.nal.usda.gov/fdc-app.html#/food-details/468991/nutrients. Published April 1, 2019. Accessed May 8, 2021.; https://fdc.nal.usda.gov/fdc-app.html#/food-details/468991/nutrients

      196

      Montazeri RS, Fatahi S, Sohouli MH, et al. The effect of nigella sativa on biomarkers of inflammation and oxidative stress: a systematic review and meta-analysis of randomized controlled trials. J Food Biochem. 2021;45(4):e13625. https://pubmed.ncbi.nlm.nih.gov/33559935/

      197

      He T, Xu X. The influence of Nigella sativa for asthma control: a meta-analysis. Am J Emerg Med. 2020;38(3):589–93. https://pubmed.ncbi.nlm.nih.gov/31892440/

      198

      Khabbazi A, Javadivala Z, Seyedsadjadi N, Malek Mahdavi A. A systematic review of the potential effects of Nigella sativa on rheumatoid arthritis. Planta Med. 2020;86(7):457–69. https://pubmed.ncbi.nlm.nih.gov/32274788/

      199

      Tajmiri S, Abbasalizad Farhangi M, Dehghan P. Nigella Sativa treatment and serum concentrations of thyroid hormones, transforming growth factor ß (TGF-ß) and interleukin 23 (IL-23) in patients with Hashimoto’s thyroiditis. Eur J Integr Med. 2016;8(4):576–80. https://www.sciencedirect.com/science/article/abs/pii/S1876382016300208

      200

      Ardakani Movaghati MR, Yousefi M, Saghebi SA, Sadeghi Vazin M, Iraji A, Mosavat SH. Efficacy of black seed (Nigella sativa L.) on kidney stone dissolution: a randomized, double-blind, placebo-controlled, clinical trial. Phytother Res. 2019;33(5):1404–12. https://pubmed.ncbi.nlm.nih.gov/30873671/

      201

      Latiff LA, Parhizkar S, Dollah MA, Hassan ST. Alternative supplement for enhancement of reproductive health and metabolic profile among perimenopausal women: a novel role of Nigella sativa. Iran J Basic Med Sci. 2014;17(12):980–5. https://pubmed.ncbi.nlm.nih.gov/25859301/