Nanotechnology in Medicine. Группа авторов

the impact of nanoparticles on protozoa, moving ahead in the direction of toxicity and safety facets of metallic, polymeric, and mesoporous silica nanoparticles. Part III is focused on Nanotoxicology and Drug delivery. Augmenting the mechanistic insights for risk assessment of employing nanomaterials in drug delivery is the need of the hour. Consequently, this part targets the toxicity and safety aspects of incorporating nanocarriers for gene delivery, brain delivery, parenteral delivery, dermatological delivery, etc. Lastly, it encompasses the current scenario and future road map for nanotoxicity and nanosafety assessment of nanocarriers. The last part (Part IV: Nanotechnology, Ethics and Regulatory Framework) emphasizes harmonizing the procedures for safety evaluation globally and ascertaining unambiguous regulations as well as standard protocols. The part thus delivers the perceptions of nanoethics and the regulatory framework of nanotechnology in medicine.

      This book has been planned, authored, and structured for the wide spectrum of multisectoral audiences of scholars, students, practitioners, and policymakers with adequate coverage. It is intended to be a reference resource that will meet the needs of academicians, clinicians, as well as graduate and postgraduate students from nearly every field of science and engineering – toxicology, biotechnology, chemistry, physics, genetics, medical science, material science and engineering, environmental science and environmental engineering. For researchers working in the fields of nanotechnology, nanomaterials and nanocarriers, nanoengineering, nanobiotechnologies, nanomedicine and biopharmaceuticals, and other similar fields, it would be very useful.

      We are highly thankful to the authors for their excellent work in providing cutting‐edge information on the subject of their respective chapters. Their efforts will certainly enhance and update the readers' knowledge of the toxicity and safety aspects of nanomedicine. Further, we would like to express our sincere thanks to the publishers and authors of the chapters whose research work has been mentioned in the book. We are also thankful to Dr. Julia Squarr, Sarah Mellor, Rosie Hayden, Tom Marriott, and the Wiley team for their substantial cooperation and efforts in producing this book.

      Last but not the least, we believe that this edited book would inspire engagement and intervention by concerted and collaborative action by appropriate bodies to shape the nanoworld and deliver innovative solutions to address daunting medical challenges.

      25 April 2021

       Mahendra Rai

       Amravati, MH, India

       Mrunali Patel

       Anand, GJ, India

       Rashmin Patel

       Anand, GJ, India

      List of Contributors

      Nayelen Sayuri Aizawa Department of Biotechnology Engineering School of Lorena (EEL) São Paulo University (USP) Lorena, São Paulo, Brazil

      Amit Alexander National Institute of Pharmaceutical Education and Research (NIPER GUWAHATI) Department of Pharmaceuticals Ministry of Chemicals & Fertilizers Near Dr. Bhupen Hazarika Regional Govt. Film & Television Institute Sila Village, Nizsundarighopa Changsari, Kamrup (R) Guwahati, Assam, India

      Thais Francine Ribeiro Alves Laboratory of Biomaterials and Nanotechnology (LaBNUS) University of Sorocaba Sorocaba, Brazil Sorocaba Technology Park, Innovation Agency Sorocaba, Brazil

      Mansi Athalye Department of Pharmaceutics and Pharmaceutical Technology L. M. College of Pharmacy Ahmedabad, GJ, India

      Fernando Batain Laboratory of Biomaterials and Nanotechnology (LaBNUS) University of Sorocaba Sorocaba, Brazil

      Bappaditya Chatterjee Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management (SPPSPTM) NMIMS University Mumbai, MH, India

      Marco Vinícius Chaud Laboratory of Biomaterials and Nanotechnology (LaBNUS) University of Sorocaba Sorocaba, Brazil Sorocaba Technology Park, Innovation Agency Sorocaba, Brazil

      Iti Chauhan Department of Pharmaceutics I.T.S College of Pharmacy, Muradnagar Ghaziabad, UP, India

      Namdev Dhas Department of Pharmaceutics Institute of Pharmacy Nirma University Ahmedabad, GJ, India

      Nataliya N. Dremina Irkutsk Scientific Center of Surgery and Traumatology Irkutsk, Russia

Nidhi Dubey School of pharmacy Devi Ahilya Vishwavidyalaya Indore, MP, India

      Nitin Dubey IPS Academy College of Pharmacy Indore, MP, India

      Wilson Engelmann Graduate Program in Public Law University of Vale do Rio dos Sinos – UNISINOS São Leopoldo, Brazil Corporate Law and Business University of Vale do Rio dos Sinos – UNISINOS São Leopoldo, Brazil

      Anuradha Ketan Gajjar L. M. College of Pharmacy Ahmedabad, GJ, India

      Fernanda Gonçalves Department of Biotechnology Engineering School of Lorena (EEL) São Paulo University (USP) Lorena, São Paulo, Brazil

      Kartik Hariharan Department of Pharmaceutics Institute of Pharmacy Nirma University Ahmedabad, GJ, India

      Raquel Von Hohendorff Graduate Program in Public Law University of Vale do Rio dos Sinos – UNISINOS São Leopoldo, Brazil

      Josef Jampílek Department of Analytical Chemistry Faculty of Natural Sciences Comenius University Bratislava, Slovakia Institute of Neuroimmunology Slovak Academy of Sciences Bratislava, Slovakia

      Nirav Khatri Dr. Reddy’s Laboratories Ltd., Hyderabad, Telangana, India

      Talita Martins Lacerda Department of Biotechnology Engineering School of Lorena (EEL) São Paulo University (USP) Lorena, São Paulo, Brazil

      Daniele Weber S. Leal CAPES fellow at the Graduate Program in Public Law University of Vale do Rio dos Sinos – UNISINOS São Leopoldo, Brazil

      Sadhucharan Mallick Department of Chemistry Indira Gandhi National Tribal University (Central University) Amarkantak, MP, India

      Paulo Ricardo Franco Marcelino Department of Biotechnology Engineering School of Lorena (EEL) São Paulo University (USP) Lorena, São Paulo, Brazil

      Tejal Mehta Department of Pharmaceutics Institute of Pharmacy Nirma University Ahmedabad, GJ, India

      Dhaivat Parikh Department of Pharmaceutics Institute of Pharmacy Nirma University Ahmedabad, GJ, India

      Mitali Patel Maliba Pharmacy College Uka Tarsadia University Bardoli, GJ, India

Mrunali Patel Department of Pharmacy Ramanbhai Patel College of Pharmacy Charotar University of Science and Technology (CHARUSAT) CHARUSAT Campus Changa, GJ, India

      Priya Patel Department of Pharmaceutical Sciences Saurashtra University Rajkot, GJ, India

      Priyanshi Patel Maliba Pharmacy College Uka Tarsadia University Bardoli, GJ, India

      Rashmin Patel Department of Pharmacy Ramanbhai Patel College of Pharmacy Charotar University of Science and Technology, CHARUSAT Changa, GJ, India

      Ravish J. Patel Ramanbhai Patel College of Pharmacy Charotar University of Science and Technology (CHARUSAT) CHARUSAT campus Changa, India

      Viral Patel Department of Pharmaceutics Institute of Pharmacy Nirma University Ahmedabad, GJ, India

      Henrique Paiva Pereira Department of Biotechnology