NPs exhibited greater in vivo antitumoral activity compared to free doxorubicin
Cheng et al. (2012)
Cationized dextran and pullulan modified with diethyl aminoethyl methacrylate (DEAEM)
Positively charged nanocomplexes with DNA and they are cytocompatible in C6, HeLa and L929 cells. Transfection efficiency of the vectors was evaluated using p53 plasmid, which demonstrated good transfection in isolated cancer cells (C6 and HeLa)
Nanogels loaded with A. ciniformis extract inhibited cell proliferation and arrested the cell cycle at the G0/G1 phase. Induction of apoptosis occurred in a time‐ and dose‐dependent manner; expression levels of pro‐apoptotic genes were up‐regulated; down‐regulation of anti‐apoptotic and metastatic genes were detected; nanogels exhibited potent anticancer activity against AGS gastric cancer cells
Rahimivand et al. (2020)
Bacterial cellulose + Fe3O4 NPs
Magnetic materials made from tetraaza macrocyclic Schiff base bacterial cellulose ligands with magnetite nanoparticles (Fe3O4 NPs) effectively inhibited the growth of the CT26 tumor models in BALB/c mice
Chaabane et al. (2020)
Clindamycin phosphate‐xanthan gum‐ZnO NPs
NPs applied as topical anti‐inflammatory drug carrier for acne treatment
Karakuş (2019)
Chitin
Silver NPs associated with chitin/Ag nanofibers presented strong antimicrobial activity against Escherichia coli, Pseudomonas aeruginosa, and Influenza A virus
Dual‐loaded nanofibers exhibited in vitro antimicrobial activity against two strains of methicillin‐resistant S. aureus (MRSA) and Staphylococcus epidermidis
Calcium alginate/TOBC biomimetic hydrogels loaded with Zn2+ exhibited good mechanical, antimicrobial, and biological properties at Zn2+ concentration of 0.0001 wt%.
Nanofibrous membranes were tested against E. coli and S. aureus and presented good antimicrobial activity with 6.08 and 5.78 log reduction, respectively
Lin et al. (2017)
Chitosan nanofiber
Biocompatible chitosan nanofiber membranes used for bone regeneration in rabbit calvarial defects with healing effect and no evidence of inflammatory reaction
Shin et al. (2005)
Collagen/elastin nanofibers
Nanofibers coated with ECM proteins with good potential for wound dressing and scaffolds for tissue engineering
Biodegradable electrospun nanofibers of PLGA and chitin presented cell adhesion and spreading for normal human keratinocytes, and were good matrices for normal human fibroblasts
Nanofibers based on blends of dextran and PLGA were tested in terms of interaction with dermal fibroblasts considering cell viability, proliferation, attachment, migration, extracellular matrix deposition, and cytoskeleton organization, and the functional gene expressions were characterized, scaffolds with good potential to enhance the healing of chronic or trauma wounds
Metronidazole was loaded in PCL/gelatine, and a sustained release was observed and significantly prevented anaerobic bacteria colonization; cytocompatibility for drug concentrations up to 30%