Прочая образовательная литература
Различные книги в жанре Прочая образовательная литератураRisk Management Applications in Pharmaceutical and Biopharmaceutical Manufacturing
Sets forth tested and proven risk management practices in drug manufacturing Risk management is essential for safe and efficient pharmaceutical and biopharmaceutical manufacturing, control, and distribution. With this book as their guide, readers involved in all facets of drug manufacturing have a single, expertly written, and organized resource to guide them through all facets of risk management and analysis. It sets forth a solid foundation in risk management concepts and then explains how these concepts are applied to drug manufacturing. Risk Management Applications in Pharmaceutical and Biopharmaceutical Manufacturing features contributions from leading international experts in risk management and drug manufacturing. These contributions reflect the latest research, practices, and industry standards as well as the authors' firsthand experience. Readers can turn to the book for: Basic foundation of risk management principles, practices, and applications Tested and proven tools and methods for managing risk in pharmaceutical and biopharmaceutical product manufacturing processes Recent FDA guidelines, EU regulations, and international standards governing the application of risk management to drug manufacturing Case studies and detailed examples demonstrating the use and results of applying risk management principles to drug product manufacturing Bibliography and extensive references leading to the literature and helpful resources in the field With its unique focus on the application of risk management to biopharmaceutical and pharmaceutical manufacturing, this book is an essential resource for pharmaceutical and process engineers as well as safety and compliance professionals involved in drug manufacturing.
Radiochemical Syntheses, Volume 1. Radiopharmaceuticals for Positron Emission Tomography
The ultimate reference guide to the synthesis of radiopharmaceuticals The Radiochemical Syntheses series provides scientists and professionals with a comprehensive reference to proven synthetic methods for radiochemical reactions, along with step-by-step guidance on how to replicate these syntheses in the laboratory. Volume 1 in the series focuses on the synthesis and purification of radiopharmaceuticals in clinical use today. It brings together in one complete, self-contained volume a collection of monographs containing a wealth of practical information from across the literature, demonstrating in meticulous detail how to prepare radiopharmaceuticals for positron emission tomography (PET) imaging, especially in tumor studies, cardiology, and neuroscience. Readers have key experimental details culled from the literature at their fingertips, greatly simplifying the process of qualifying a site for the clinical production of new radiopharmaceuticals.
Introduction to Magnetic Random-Access Memory
Magnetic random-access memory (MRAM) is poised to replace traditional computer memory based on complementary metal-oxide semiconductors (CMOS). MRAM will surpass all other types of memory devices in terms of nonvolatility, low energy dissipation, fast switching speed, radiation hardness, and durability. Although toggle-MRAM is currently a commercial product, it is clear that future developments in MRAM will be based on spin-transfer torque, which makes use of electrons’ spin angular momentum instead of their charge. MRAM will require an amalgamation of magnetics and microelectronics technologies. However, researchers and developers in magnetics and in microelectronics attend different technical conferences, publish in different journals, use different tools, and have different backgrounds in condensed-matter physics, electrical engineering, and materials science. This book is an introduction to MRAM for microelectronics engineers written by specialists in magnetic materials and devices. It presents the basic phenomena involved in MRAM, the materials and film stacks being used, the basic principles of the various types of MRAM (toggle and spin-transfer torque; magnetized in-plane or perpendicular-to-plane), the back-end magnetic technology, and recent developments toward logic-in-memory architectures. It helps bridge the cultural gap between the microelectronics and magnetics communities.
Applied Impact Mechanics
This book is intended to help the reader understand impact phenomena as a focused application of diverse topics such as rigid body dynamics, structural dynamics, contact and continuum mechanics, shock and vibration, wave propagation and material modelling. It emphasizes the need for a proper assessment of sophisticated experimental/computational tools promoted widely in contemporary design. A unique feature of the book is its presentation of several examples and exercises to aid further understanding of the physics and mathematics of impact process from first principles, in a way that is simple to follow.
Beyond Foundations. Developing as a Master Academic Advisor
Sharpen advising expertise by exploring critical issues affecting the field Beyond Foundations, a core resource for experienced academic advisors, gives practitioners insight into important issues affecting academic advising. In addition to gaining understanding of foundational concepts and pressing concerns, master advisors engage with case studies to clarify their roles as educators of students, as thought leaders in institutions, and as advocates for the profession. Pillar documents—the NACADA Core Values, NACADA Concept of Academic Advising, and CAS Standards—serve as sources of both information and inspiration for those seeking to improve advising. New strategies inform advisors helping a diverse student population delineate meaningful educational goals. Each chapter prompts productive discussions with fellow advisors interested in cultivating advising excellence. To promote advisor influence in higher education, experienced contributors explain new trends—including the impact of external forces and legal issues on postsecondary institutions—and the evolution of advising as a profession and a field of inquiry. Expert insight and practical focus contribute to the development of experienced advisors. Use existing resources in new ways to master advising roles and encourage student success Apply theory to advance advising practice Create and optimize professional development opportunities Establish recognition for the contributions of academic advisors to the institution and higher education Face challenges created by the changing higher education landscape Advisors must meet the expectations of students, parents, faculty members, administrators, and outside agencies, all while navigating an increasingly complex range of issues presented by a student population unlike any that has come before. Beyond Foundations provides the insight and clarity advisors need to help students achieve their educational goals and to advance the field.
Continuous Manufacturing of Pharmaceuticals
A comprehensive look at existing technologies and processes for continuous manufacturing of pharmaceuticals As rising costs outpace new drug development, the pharmaceutical industry has come under intense pressure to improve the efficiency of its manufacturing processes. Continuous process manufacturing provides a proven solution. Among its many benefits are: minimized waste, energy consumption, and raw material use; the accelerated introduction of new drugs; the use of smaller production facilities with lower building and capital costs; the ability to monitor drug quality on a continuous basis; and enhanced process reliability and flexibility. Continuous Manufacturing of Pharmaceuticals prepares professionals to take advantage of that exciting new approach to improving drug manufacturing efficiency. This book covers key aspects of the continuous manufacturing of pharmaceuticals. The first part provides an overview of key chemical engineering principles and the current regulatory environment. The second covers existing technologies for manufacturing both small-molecule-based products and protein/peptide products. The following section is devoted to process analytical tools for continuously operating manufacturing environments. The final two sections treat the integration of several individual parts of processing into fully operating continuous process systems and summarize state-of-art approaches for innovative new manufacturing principles. Brings together the essential know-how for anyone working in drug manufacturing, as well as chemical, food, and pharmaceutical scientists working on continuous processing Covers chemical engineering principles, regulatory aspects, primary and secondary manufacturing, process analytical technology and quality-by-design Contains contributions from researchers in leading pharmaceutical companies, the FDA, and academic institutions Offers an extremely well-informed look at the most promising future approaches to continuous manufacturing of innovative pharmaceutical products Timely, comprehensive, and authoritative, Continuous Manufacturing of Pharmaceuticals is an important professional resource for researchers in industry and academe working in the fields of pharmaceuticals development and manufacturing.
Emerging Pollutants. Origin, Structure, and Properties
An excellent, concise, and interdisciplinary overview of different classes of emerging pollutants arising, for example, from pharmaceuticals, pesticides, personal care products, and industrial chemicals and their impact on water, soil, and air. Following an introduction to chemical pollutants, with special attention focused on organic compounds and their properties, the book goes on to describe major emerging pollutants grouped according to their applications in different sectors of industrial or economic activity. For each type of compound, the chemical structure, main properties, and source are presented, along with their fate in the environment as pollutants, the latest analytical methods for detection, possible health or ecology consequences, as well as current regulatory laws. New developments, such as nanotechnology as a pollution source, are also included. The book closes with a chapter devoted to conclusions and future perspectives.
Fluid Dynamics in Complex Fractured-Porous Systems
Despite of many years of studies, predicting fluid flow, heat, and chemical transport in fractured-porous media remains a challenge for scientists and engineers worldwide. This monograph is the third in a series on the dynamics of fluids and transport in fractured rock published by the American Geophysical Union (Geophysical Monograph Series, Vol. 162, 2005; and Geophysical Monograph, No. 122, 2000). This monograph is dedicated to the late Dr. Paul Witherspoon for his seminal influence on the development of ideas and methodologies and the birth of contemporary fractured rock hydrogeology, including such fundamental and applied problems as environmental remediation; exploitation of oil, gas, and geothermal resources; disposal of spent nuclear fuel; and geotechnical engineering. This monograph addresses fundamental and applied scientific questions and is intended to assist scientists and practitioners bridge gaps in the current scientific knowledge in the areas of theoretical fluids dynamics, field measurements, and experiments for different practical applications. Readers of this book will include researchers, engineers, and professionals within academia, Federal agencies, and industry, as well as graduate/undergraduate students involved in theoretical, experimental, and numerical modeling studies of fluid dynamics and reactive chemical transport in the unsaturated and saturated zones, including studies pertaining to petroleum and geothermal reservoirs, environmental management and remediation, mining, gas storage, and radioactive waste isolation in underground repositories. Volume highlights include discussions of the following: Fundamentals of using a complex systems approach to describe flow and transport in fractured-porous media. Methods of Field Measurements and Experiments Collective behavior and emergent properties of complex fractured rock systems Connection to the surrounding environment Multi-disciplinary research for different applications
Affirmative Counseling with LGBTQI+ People
This current and comprehensive handbook will guide educators, students, and clinicians in developing the awareness, knowledge, and skills necessary to work effectively with LGBTQI+ populations. Twenty-five chapters written by experts in the field provide direction for working with clients in an authentic, ethical, and affirmative manner that is tailored to their individual strengths, needs, and identity. The book is divided into four sections, which explore the science behind gender and affectional orientation; developmental issues across the life span and treatment issues; the specialized needs of nine distinct populations; and the intersectionality of ethnicity and overlapping identities, the role of religion, and counselor advocacy. To further a deeper understanding of the content, each chapter contains an «Awareness of Attitudes and Beliefs Self-Check,» a case narrative relating to the material covered, questions for discussion, and a list of online resources. The book concludes with an extensive glossary of terms, both preferred and problematic, which counselors working with these communities should understand and use appropriately.
The New Advisor Guidebook. Mastering the Art of Academic Advising
This is an exciting time to be an academic advisor—a time in which global recognition of the importance of advising is growing, research affirms the critical role advising plays in student success, and institutions of higher education increasingly view advising as integral to their missions and essential for improving the quality of students' educational experiences. It is essential that advisors provide knowledgeable, realistic counsel to the students in their charge. The New Advisor Guidebook helps advisors meet this challenge. The first and final chapters of the book identify the knowledge and skills advisors must master. These chapters present frameworks for setting and benchmarking self-development goals and for creating self-development plans. Each of the chapters in between focuses on foundational content: the basic terms, concepts, information, and skills advisors must learn in their first year and upon which they will build over the lengths of their careers. These chapters include strategies, questions, guidelines, examples, and case studies that give advisors the tools to apply this content in their work with students, from demonstrations of how student development theories might play out in advising sessions to questions advisors can ask to become aware of their biases and avoid making assumptions about students to a checklist for improving listening, interviewing, and referral skills. The book covers various ways in which advising is delivered: one-to-one, in groups, and online. The New Advisor Guidebook serves as an introduction to what advisors must know to do their jobs effectively. It pairs with Academic Advising Approaches: Strategies That Teach Students to Make the Most of College, also from NACADA, which presents the delivery strategies successful advisors can use to help students make the most of their college experience.