Прочая образовательная литература
Различные книги в жанре Прочая образовательная литератураThe Role of the Study Director in Nonclinical Studies. Pharmaceuticals, Chemicals, Medical Devices, and Pesticides
A single-source reference with a broad and holistic overview of nonclinical studies, this book offers critical training material and describes regulations of nonclinical testing through guidelines, models, case studies, practical examples, and worldwide perspectives. The book: Provides a complete overview of nonclinical study organization, conduct, and reporting and describes the roles and responsibilities of a Study Director to manage an effective study Covers regulatory and scientific concepts, including international testing and Good Laboratory Practice (GLP), compliance with guidelines, and animal models Features a concluding chapter that compiles case studies / lessons learned from those that have served as a Study Director for many years Addresses the entire spectrum of nonclinical testing, making it applicable to those in the government, laboratories and those actively involved in in all sectors of industry
Medicinal Chemistry Approaches to Personalized Medicine
Edited by two renowned medicinal chemists who have pioneered the development of personalized therapies in their respective fields, this authoritative analysis of what is already possible is the first of its kind, and the only one to focus on drug development issues. Numerous case studies from the first generation of «personalized drugs» are presented, highlighting the challenges and opportunities for pharmaceutical development. While the majority of these examples are taken from the field of cancer treatment, other key emerging areas, such as neurosciences and inflammation, are also covered. With its careful balance of current and future approaches, this handbook is a prime knowledge source for every drug developer, and one that will remain up to date for some time to come. From the content: * Discovery of Predictive Biomarkers for Anticancer Drugs * Discovery and Development of Vemurafenib * Targeting Basal-Cell Carcinoma * G-Quadruplexes as Therapeutic Targets in Cancer * From Human Genetics to Drug Candidates: An Industrial Perspective on LRRK2 Inhibition as a Treatment for Parkinson's Disease * Therapeutic Potential of Kinases in Asthma * DNA Damage Repair Pathways and Synthetic Lethality * Medicinal Chemistry in the Context of the Human Genome and many more
Molekularbiologie. für Biologen, Biochemiker, Pharmazeuten und Mediziner
Kompakt und »verdammt clever« auf den Punkt gebracht – vermittelt Molekularbiologie das unverzichtbare Grundwissen zu Struktur, Biosynthese und Funktion von DNA und RNA und erklärt, wie diese untereinander und mit Proteinen interagieren. Endlich ein maßgeschneidertes Kurzlehrbuch für Studenten, die auf der Suche nach einer knappen Einführung in dieses grundlegende Fachgebiet sind: • Ideal für Einsteiger! Beschränkt sich auf die wirklich wichtigen Themen der Molekularbiologie und fasst die wesentlichen Fakten und Begriffe für jedes Thema zusammen. • Einprägsam! Klare Abbildungen erleichtern das Lernen und Verstehen, Querverweise auf verwandte Kapitel zeigen Zusammenhänge auf und fördern so das Verständnis. • Ausgezeichnete Prüfungsvorbereitung! Ermöglicht strukturiertes Lernen und schnelles Wiederholen durch einzigartigen Kapitelaufbau – mit über 70 Fragen und Antworten.
The Social Change Model. Facilitating Leadership Development
A comprehensive guide to using the Social Change Model in all types of curricular and co-curricular settings This book is designed to provide leadership educators with a wealth of classroom and workshop activities, discussion and reflection questions, assignment suggestions, and additional resources such as video clips and supplementary readings. It also includes several case studies for students to consider the implications of applying all eight elements of the Social Change Model in a variety of contexts. The Social Change Model of Leadership Development—upon which the book is based—was designed by well-known leadership educators and received wide acclaim and use. The validity of this model has been established through a number of research studies including the Multi-Institutional Study of Leadership. Written by leading experts and developers of the Social Change Model who often present and consult on the topic Helps curricular and co-curricular leadership educators teach the Social Change Model through individual and group activities, reflection questions, and discussion questions. Walks course or workshop facilitators through the entire process of teaching the content and facilitating and debriefing activities If you're a leadership educator of high school, undergraduate, or graduate school students, The Social Change Model: Facilitating Leadership Development is indispensable reading. Please note that The Social Change Model: Facilitating Leadership Development is intended to be used as a Facilitator's Guide to Leadership for a Better World, 2nd Edition (978-1-119-20759-7) in seminars, workshops, and college classrooms. You'll find that, while each book can be used on its own, the content in both is also designed for use together. A link to the home page of Leadership for a Better World can be found below under Related Titles.
College Student Mental Health. New Directions for Student Services, Number 156
In recent years, there has been heightened attention paid to the mental health needs of college students, the range and scope of these issues, and the challenges related to providing mental health services. Counseling center data, changing legal mandates and anecdotal reports from senior practitioners all point to the growing complexity of managing these issues. This volume examines clinical issues for student affairs professionals beyond the counseling center– addressing how campuses can be prepared for and respond to mental health issues. It helps readers cultivate a community-centered understanding of and sense of shared responsibility for promoting mental health, knowledge about best practices for service provision, and strategies for dealing with mental health issues pertaining to specific student populations and issues within the environment. Topics covered include: Contextual and foundational information related to current student mental health trends, Mental health aspects of certain populations including military-connected students, students on the autism spectrum, and international student, Bigger-picture, systemic issues related to mental health faced by colleges and universities, and Future directions of mental health on campuses. This is the 156th volume of this Jossey-Bass higher education quarterly series. An indispensable resource for vice presidents of student affairs, deans of students, student counselors, and other student services professionals, New Directions for Student Services offers guidelines and programs for aiding students in their total development: emotional, social, physical, and intellectual.
An Introduction to Human-Environment Geography. Local Dynamics and Global Processes
This introductory level text explores various theoretical approaches to human-environment geography, demonstrating how local dynamics and global processes influence how we interact with our environments. Introduces students to fundamental concepts in environmental geography and science Explores the core theoretical traditions within the field, along with major thematic issues such as population, food and agriculture, and water resources Offers an engaging and unique view of the spatial relationships between humans and their environment across geographical locations around the world Includes a variety of real-world policy questions and emphasizes geography’s strong tradition of field work by featuring prominent nature-society geographers in guest field notes
The Wiley Blackwell Companion to Political Geography
The Wiley Blackwell Companion to Political Geography aims to account for the intellectual and worldly developments that have taken place in and around political geography in the last 10 years. Bringing together established names in the field as well as new scholars, it highlights provocative theoretical and conceptual debates on political geography from a range of global perspectives. Discusses the latest developments and places increased emphasis on modes of thinking, contested key concepts, and on geopolitics, climate change and terrorism Explores the influence of the practice-based methods in geography and concepts including postcolonialism, feminist geographies, the notion of the Anthropocene, and new understandings of the role of non-human actors in networks of power Offers an accessible introduction to political geography for those in allied fields including political science, international relations, and sociology
Reinforced Concrete Beams, Columns and Frames. Section and Slender Member Analysis
This book is focused on the theoretical and practical design of reinforced concrete beams, columns and frame structures. It is based on an analytical approach of designing normal reinforced concrete structural elements that are compatible with most international design rules, including for instance the European design rules – Eurocode 2 – for reinforced concrete structures. The book tries to distinguish between what belongs to the structural design philosophy of such structural elements (related to strength of materials arguments) and what belongs to the design rule aspects associated with specific characteristic data (for the material or loading parameters). A previous book, entitled Reinforced Concrete Beams, Columns and Frames – Mechanics and Design, deals with the fundamental aspects of the mechanics and design of reinforced concrete in general, both related to the Serviceability Limit State (SLS) and the Ultimate Limit State (ULS), whereas the current book deals with more advanced ULS aspects, along with instability and second-order analysis aspects. Some recent research results including the use of non-local mechanics are also presented. This book is aimed at Masters-level students, engineers, researchers and teachers in the field of reinforced concrete design. Most of the books in this area are very practical or code-oriented, whereas this book is more theoretically based, using rigorous mathematics and mechanics tools. Contents 1. Advanced Design at Ultimate Limit State (ULS). 2. Slender Compression Members – Mechanics and Design. 3. Approximate Analysis Methods. Appendix 1. Cardano’s Method. Appendix 2. Steel Reinforcement Table. About the Authors Jostein Hellesland has been Professor of Structural Mechanics at the University of Oslo, Norway since January 1988. His contribution to the field of stability has been recognized and magnified by many high-quality papers in famous international journals such as Engineering Structures, Thin-Walled Structures, Journal of Constructional Steel Research and Journal of Structural Engineering. Noël Challamel is Professor in Civil Engineering at UBS, University of South Brittany in France and chairman of the EMI-ASCE Stability committee. His contributions mainly concern the dynamics, stability and inelastic behavior of structural components, with special emphasis on Continuum Damage Mechanics (more than 70 publications in International peer-reviewed journals). Charles Casandjian was formerly Associate Professor at INSA (French National Institute of Applied Sciences), Rennes, France and the chairman of the course on reinforced concrete design. He has published work on the mechanics of concrete and is also involved in creating a web experience for teaching reinforced concrete design – BA-CORTEX. Christophe Lanos is Professor in Civil Engineering at the University of Rennes 1 in France. He has mainly published work on the mechanics of concrete, as well as other related subjects. He is also involved in creating a web experience for teaching reinforced concrete design – BA-CORTEX.
Recent Advances in Polyphenol Research, Volume 5
Plant polyphenols are secondary metabolites that constitute one of the most common and widespread groups of natural products. They express a large and diverse panel of biological activities including beneficial effects on both plants and humans. Many polyphenols, from their structurally simplest representatives to their oligo/polymeric versions (also referred to as vegetable tannins), are notably known as phytoestrogens, plant pigments, potent antioxidants, and protein interacting agents. Sponsored by the scholarly society Groupe Polyphénols, this publication, which is the fifth volume in this highly regarded Recent Advances in Polyphenol Research series, is edited by Kumi Yoshida, Véronique Cheynier and Stéphane Quideau. They have once again, like their predecessors, put together an impressive collection of cutting-edge chapters written by expert scientists, internationally respected in their respective field of polyphenol sciences. This Volume 5 highlights some of the latest information and opinion on the following major research topics about polyphenols: • Chemistry, physicochemistry & materials science • Biosynthesis, genetic & metabolic engineering • Plant & ecosystem, lignocellulosic biomass • Food, nutrition & health • Natural medicine & Kampo • Tannins & their functions Chemists, biochemists, plant scientists, pharmacognosists and pharmacologists, biologists, ecologists, food scientists and nutritionists will all find this book an invaluable resource. Libraries in all universities and research institutions where these disciplines are studied and taught should have copies on their bookshelves.
Emotionally Intelligent Leadership for Students. Inventory
The only instrument that measures behaviors associated with emotionally intelligent leadership The Emotionally Intelligent Leadership for Students: Inventory is an evidence-based assessment of the capacities of emotionally intelligent leadership (EIL). Research that spans the globe has demonstrated that there is a relationship between emotional intelligence and leadership. For the second edition, the authors have conducted original studies, yielding a substantial revision that better reflects the world of emotionally intelligent leadership and will be transformative for students of all backgrounds. First, this 57-item assessment measures how often students engage in behaviors that align with emotionally intelligent leadership. Then, the reflection portion walks students through the process of analyzing and understanding their results, giving them concrete suggestions for how to explore and improve their emotionally intelligent leadership. The inventory reflects 19 EIL capacities supported by recent studies A section on guided interpretation allows students to determine next steps to help them prepare to become effective leaders Guidance for reflection and analysis of the results introduces learning opportunities that align with unique learning styles Use the inventory along with Emotionally Intelligent Leadership: A Guide for Students and its Student Workbook for an immersive and transformative educational experience. Students will appreciate the opportunity to learn more about themselves as they reflect on their experiences as learners and their own leadership journeys.