Прочая образовательная литература
Различные книги в жанре Прочая образовательная литератураBatch Effects and Noise in Microarray Experiments. Sources and Solutions
Batch Effects and Noise in Microarray Experiments: Sources and Solutions looks at the issue of technical noise and batch effects in microarray studies and illustrates how to alleviate such factors whilst interpreting the relevant biological information. Each chapter focuses on sources of noise and batch effects before starting an experiment, with examples of statistical methods for detecting, measuring, and managing batch effects within and across datasets provided online. Throughout the book the importance of standardization and the value of standard operating procedures in the development of genomics biomarkers is emphasized. Key Features: A thorough introduction to Batch Effects and Noise in Microrarray Experiments. A unique compilation of review and research articles on handling of batch effects and technical and biological noise in microarray data. An extensive overview of current standardization initiatives. All datasets and methods used in the chapters, as well as colour images, are available on www.the-batch-effect-book.org, so that the data can be reproduced. An exciting compilation of state-of-the-art review chapters and latest research results, which will benefit all those involved in the planning, execution, and analysis of gene expression studies.
Assessing the Generic Outcomes of College. Selections from Assessment Measures
What does college teach, really? As demands for accountability intensify, meaningful measurement of broad college outcomes becomes increasingly important. Here, you'll take a journey through the history of assessment instruments, starting with the creation of the first general outcomes assessment tools in the 1980s. You'll follow the evolution of the tools, writing and critical thinking, and finally the concept of value-added analysis, an appealing but elusive goal for assessors.
Organic Mechanisms. Reactions, Methodology, and Biological Applications
Instills a deeper understanding of how and why organic reactions happen Integrating reaction mechanisms, synthetic methodology, and biological applications, Organic Mechanisms gives organic chemists the tools needed to perform seamless organic reactions. By explaining the underlying mechanisms of organic reactions, author Xiaoping Sun makes it possible for readers to gain a deeper understanding of not only chemical phenomena, but also the ability to develop new synthetic methods. Moreover, by emphasizing biological applications, this book enables readers to master both advanced organic chemistry theory and practice. Organic Mechanisms consists of ten chapters, beginning with a review of fundamental physicochemical principles that are essential for understanding the nature of organic mechanisms. Each one of the remaining chapters is devoted to a major class of organic reactions, including: Aliphatic C–H bond functionalization Functionalization of the alkene C=C bond by cycloaddition reactions Nucleophilic substitutions on sp3-hybridized carbons Nucleophilic additions and substitutions on carbonyl groups Reactivity of the α-hydrogen to carbonyl groups Rearrangements A brief review of basic organic chemistry begins each chapter, helping readers move from fundamental concepts to an advanced understanding of reaction mechanisms. Key mechanisms are illustrated by expertly drawn figures highlighting microscopic details. End-of-chapter problems enable readers to put their newfound knowledge into practice by solving key problems in organic reactions with the use of mechanistic studies, and a Solutions Manual is available online for course instructors. Thoroughly referenced and current with recent findings in organic reaction mechanisms, Organic Mechanisms is recommended for upper-level undergraduates and graduate students in advanced organic chemistry, as well as for practicing chemists who want to further explore the mechanistic aspects of organic reactions.
Paleomagnetism of Sedimentary Rocks. Process and Interpretation
This book describes the paleomagnetism of sediments and sedimentary rocks, how sediments and sedimentary rocks become magnetized, and how the physical and chemical processes involved can affect the accuracy of paleomagnetism. Topics covered include depositional and post-depositional remanence acquisition, the detection and correction of compaction-caused inclination shallowing, reduction diagenesis of magnetic minerals, chemical remagnetization, and rotation of remanence by grain-scale rock strain. The book also has a chapter on environmental paleomagnetism, including examples of the new technique of high-resolution rock magnetic cyclostratigraphy and its application to sedimentary sequences. By emphasising the accuracy of sedimentary paleomagnetism and the magnitude of post-depositional processes that can affect it, the book will be invaluable in the geologic interpretation of sedimentary paleomagnetic data. Paleomagnetism of Sedimentary Rocks will be welcomed by paleomagnetists, students of paleomagnetism and all Earth scientists who use sedimentary paleomagnetic data in their research. Additional resources for this book can be found at: www.wiley.com/go/kodama/paleomagnetism.
Inorganic Chemical Biology. Principles, Techniques and Applications
Understanding, identifying and influencing the biological systems are the primary objectives of chemical biology. From this perspective, metal complexes have always been of great assistance to chemical biologists, for example, in structural identification and purification of essential biomolecules, for visualizing cellular organelles or to inhibit specific enzymes. This inorganic side of chemical biology, which continues to receive considerable attention, is referred to as inorganic chemical biology. Inorganic Chemical Biology: Principles, Techniques and Applications provides a comprehensive overview of the current and emerging role of metal complexes in chemical biology. Throughout all of the chapters there is a strong emphasis on fundamental theoretical chemistry and experiments that have been carried out in living cells or organisms. Outlooks for the future applications of metal complexes in chemical biology are also discussed. Topics covered include: • Metal complexes as tools for structural biology • IMAC, AAS, XRF and MS as detection techniques for metals in chemical biology • Cell and organism imaging and probing DNA using metal and metal carbonyl complexes • Detection of metal ions, anions and small molecules using metal complexes • Photo-release of metal ions in living cells • Metal complexes as enzyme inhibitors and catalysts in living cells Written by a team of international experts, Inorganic Chemical Biology: Principles, Techniques and Applications is a must-have for bioinorganic, bioorganometallic and medicinal chemists as well as chemical biologists working in both academia and industry.
Radio Receiver Technology. Principles, Architectures and Applications
Written by an expert in the field, this book covers the principles, architectures, applications, specifications and characterizations of radio receivers In this book, the author introduces the reader to the basic principles and theories of present-day communications receiver technology. The first section of the book presents realization concepts at the system level, taking into consideration the various types of users. Details of the circuitry are described providing the reader with an understanding of fully digitized radio receivers, offering an insight into the state-of-the-art. The remaining sections address radio receivers, particularly as two-port devices. Furthermore, the author outlines the fields of applications (with sample calculations and with reference to practical work) and their features and considers also the specialty of high-quality radio receivers. As can be seen from the multitude of terrestrial applications described in Part II, they are typically used for radio surveillance, signal intelligence, modern radio bearing and at the classical radio services. Parts III and IV describe the entire range of parameters that are useful for the characterization of these receivers. The description starts from the physical effect, or the explanation of the individual parameter, and then proceeds to the measuring technique for determining the parameters, highlighting problems, followed by explanatory notes with applicatory relevance. The measuring procedures described are the result of experiences gained in extended laboratory work and practical testing. With the model shown in Part IV, used for the operational evaluation detailing the intrinsic small range of interpretation, the book covers untreated research in the field. The Appendix provides among others valuable information about the dimensioning of receiving systems and the mathematical derivation of non-linear effects and as well as a useful method for converting different level specifications. Key Features: Introduces the basic principles and theories of present-day technology Discusses concepts at system level (aligned to the various types of users) Addresses (fully) digitized radio receivers focusing on the state-of-the-art Close contacts to the industry were utilized to show background information Enables the reader to comprehend and evaluate the characteristic features and the performance of such systems Examines the entire range of parameters that are characteristic of the technology including the physical effect and measuring techniques Includes results of experiences gained in extended laboratory work and practical testing with examples Provides a uniform and systematic approach for ease of understanding e.g. many didactic figures for the visual illustration have been newly created as well as complete real-world examples This book will be an excellent resource to understand the principles of work, for professionals developing and testing radio receivers, for receiver users (e.g. at regulatory agencies, surveillance centers, secret services, classical radio communications services), technicians, engineers and technicians who work with RF-measurement instruments, postgraduate students studying in the field and university lecturers. Chartered radio amateurs and handlers/operators will also find this book insightful. Due to high level of detail, it also serves as a reference. By using the carefully edited alphabetical index with over 1,200 entries, the appropriate explanations can be found quickly in the text.
Do Species Exist? Principles of Taxonomic Classification
A readily comprehensible guide for biologists, field taxonomists and interested laymen to one of the oldest problems in biology: the species problem. Written by a geneticist with extensive experience in field taxonomy, this practical book provides the sound scientific background to the problems arising with classifying organisms according to species. It covers the main current theories of specification and gives a number of examples that cannot be explained by any single theory alone.
Biogas Production. Pretreatment Methods in Anaerobic Digestion
This volume covers the most cutting-edge pretreatment processes being used and studied today for the production of biogas during anaerobic digestion processes using different feedstocks, in the most efficient and economical methods possible. As an increasingly important piece of the «energy pie,» biogas and other biofuels are being used more and more around the world in every conceivable area of industry and could be a partial answer to the energy problem and the elimination of global warming.
HOAI 2013. Praxisleitfaden für Ingenieure und Architekten
Mit der 7. Novelle der HOAI sind erneut umfangreiche Änderungen in der Honorarermittlung der Ingenieure und Architekten umgesetzt worden. Die Leistungsbilder wurden überarbeitet, den aktuellen Anforderungen angepasst und neue Grundleistungen aufgenommen. In diesem Zuge wurde auch die Bewertung der einzelnen Leistungsphasen angepasst. Darüber hinaus ist die Berücksichtigung der vorhandenen Bausubstanz wieder eingeführt und die Regelungen zum Umbauzuschlag erneut umgestellt worden. Das vorliegende Werk hilft bei der schnellstmöglichen Einarbeitung in die HOAI 2013. Neben einer praxisorientierten Einführung bietet es bewährte Arbeitshilfen sowie den kompletten aktuellen Verordnungstext.
Bachelor 40plus. Plädoyer für ein neues Bildungskonzept
Nahezu unser gesamtes Bildungsbudget wird in die ersten Lebensphasen investiert, obwohl die hier vermittelten Fähigkeiten und das fachliche Wissen nach zehn oder 20 Jahren überholt sind. Die deutsche Wirtschaft braucht Menschen über 40, die ausschließliche Konzentration auf die Aus- und Weiterbildung junger Menschen ist ein Indiz gesellschaftspolitischen Versagens. Wir benötigen ein bedarfsorientiertes Bildungssystem mit einem neuen, quartären Sektor, der sich an ältere Teilnehmer richtet, die bereits 15 bis 20 Jahre Berufstätigkeit hinter sich und mindestens noch eine solche Spanne vor sich haben. Der neue Sektor erfüllt aber noch weitere Zwecke. Die längeren Lebensarbeitszeiten mit vielfältigen Neuorientierungen und die geringere Anzahl klassischer Karrieren werden dazu führen, dass viele Menschen ihr Leben anders als bisher gestalten wollen. Ausstieg, Umstieg und Neueinstieg werden künftig weniger als Krise denn als Perspektive verstanden, mit den bisher gewonnenen Erfahrungen nochmals neu anzufangen. Zum Beispiel mit einem Bachelor 40plus. Es ist höchste Zeit, alters-, qualifikations- und motivationsentsprechende Bildungsformen und -inhalte zu entwickeln. Dieses Buch stellt Wege für Unternehmen, Hochschulen, private Business Schools, Staat und Gesellschaft vor, auf denen ältere und berufserfahrene Beschäftigte ihre Employability sichern und erweitern können.