An emerging field at the interface of biology and engineering, mechanobiology explores the mechanisms by which cells sense and respond to mechanical signals—and holds great promise in one day unravelling the mysteries of cellular and extracellular matrix mechanics to cure a broad range of diseases. Mechanobiology: Exploitation for Medical Benefit presents a comprehensive overview of principles of mechanobiology, highlighting the extent to which biological tissues are exposed to the mechanical environment, demonstrating the importance of the mechanical environment in living systems, and critically reviewing the latest experimental procedures in this emerging field. Featuring contributions from several top experts in the field, chapters begin with an introduction to fundamental mechanobiological principles; and then proceed to explore the relationship of this extensive force in nature to tissues of musculoskeletal systems, heart and lung vasculature, the kidney glomerulus, and cutaneous tissues. Examples of some current experimental models are presented conveying relevant aspects of mechanobiology, highlighting emerging trends and promising avenues of research in the development of innovative therapies. Timely and important, Mechanobiology: Exploitation for Medical Benefit offers illuminating insights into an emerging field that has the potential to revolutionise our comprehension of appropriate cell biology and the future of biomedical research.
Adopting a novel approach to the topic by combining theoretical knowledge and practical results, this book presents the most popular and useful computational and experimental methods applied for studying the stereochemistry of chemical reactions and compounds. The text is clearly divided into three sections on fundamentals, spectroscopic and computational techniques, and applications in organic synthesis. The first part provides a brief introduction to the field of chirality and stereochemistry, while the second part covers the different methodologies, such as optical rotation, electronic circular dichroism, vibrational circular dicroism, and Raman spectroscopy. The third section then goes on to describe selective examples in organic synthesis, classified by reaction type, i.e. enantioselective, chemoselective and stereoselective reactions. A final chapter on total synthesis of natural products rounds off the book. A valuable reference for researchers in academia and industry working in the field of organic synthesis, computational chemistry, spectroscopy or medicinal chemistry.
A comprehensive review of the fundamentals aspects of combustion, covering fundamental thermodynamics and chemical kinetics through to practical burners. It provides a detailed analysis of the basic ideas and design characteristics of burners for gaseous, liquid and solid fuels. End of chapter review questions help the reader to evaluate their understanding of both the fundamental as well as the application aspects. Furthermore, a chapter on alternative renewable fuels has been included to bring out the need, characteristics and usage of alternative fuels along with fossil fuels. A section on future trends in fuels and burners is also provided. Several key research articles have been cited in the text and listed in the references.
The engineer's ready reference for mechanical power and heat Mechanical Engineer's Handbook provides the most comprehensive coverage of the entire discipline, with a focus on explanation and analysis. Packaged as a modular approach, these books are designed to be used either individually or as a set, providing engineers with a thorough, detailed, ready reference on topics that may fall outside their scope of expertise. Each book provides discussion and examples as opposed to straight data and calculations, giving readers the immediate background they need while pointing them toward more in-depth information as necessary. Volume 4: Energy and Power covers the essentials of fluids, thermodynamics, entropy, and heat, with chapters dedicated to individual applications such as air heating, cryogenic engineering, indoor environmental control, and more. Readers will find detailed guidance toward fuel sources and their technologies, as well as a general overview of the mechanics of combustion. No single engineer can be a specialist in all areas that they are called on to work in the diverse industries and job functions they occupy. This book gives them a resource for finding the information they need, with a focus on topics related to the productions, transmission, and use of mechanical power and heat. Understand the nature of energy and its proper measurement and analysis Learn how the mechanics of energy apply to furnaces, refrigeration, thermal systems, and more Examine the and pros and cons of petroleum, coal, biofuel, solar, wind, and geothermal power Review the mechanical parts that generate, transmit, and store different types of power, and the applicable guidelines Engineers must frequently refer to data tables, standards, and other list-type references, but this book is different; instead of just providing the answer, it explains why the answer is what it is. Engineers will appreciate this approach, and come to find Volume 4: Energy and Power an invaluable reference.
Examines new cooperative control methodologies tailored to real-world applications in various domains such as in communication systems, physics systems, and multi-robotic systems Provides the fundamental mechanism for solving collective behaviors in naturally-occurring systems as well as cooperative behaviors in man-made systems Discusses cooperative control methodologies using real-world applications, including semi-conductor laser arrays, mobile sensor networks, and multi-robotic systems Includes results from the research group at the Stevens Institute of Technology to show how advanced control technologies can impact challenging issues, such as high energy systems and oil spill monitoring
Die zweite Auflage eines Standardwerks: Alle wichtigen Aspekte und Techniken der Elektrophorese werden abgedeckt, von SDS-PAGE und Isotachophorese bis zu isoelektrischer Fokussierung, blauer Nativ-Elektrophorese und zweidimensionalen Methoden. Speziell auf die Bedurfnisse von Laboranten und technischen Angestellten zugeschnitten, stehen praktische Gesichtspunkte und Methoden im Mittelpunkt des Buchs. Nach einem Uberblick uber alle gangigen Elektrophoresetechniken mit einer Einfuhrung in Detektion, Musterauswertung und Proteomik folgen Kapitel zu Instrumentierung und benotigten Arbeitsmaterialien. Detaillierte Methodenanleitungen erleichtern auch dem Anfanger den praktischen Einstieg in die Welt der Elektrophorese. Die Begleitwebsite mit zahlreichen Animationen ermoglicht einen zusatzlichen visuellen Zugang zu den einzelnen Techniken.
Zeitgema?es Wissen in Lekture- und in Lehrbuchform. Gerhard Gottschalk vermittelt die Mikrobiologie in ihrer ganzen Breite. In 12 Teilen mit jeweils mehreren Kapiteln wird die Mikrobiologie dem Leser auf sehr verstandliche Weise nahergebracht. Jedes Kapitel besteht aus einer leicht zu lesenden Beschreibung und darauf abgestimmter Lerneinheit samt Fragenkatalog. Daruber hinaus enthalten die meisten Kapitel Beitrage beruhmter Wissenschaftler auf dem entsprechenden Gebiet. Historische Durchbruche werden beschrieben und so den Studierenden Einblicke in Denk- und Planungsstrukturen von wissenschaftlichem Arbeiten vermittelt. So beschreibt beispielsweise Stefan Hell seine 2014 mit dem Nobelpreis gekronte STED-Mikroskopie. Alle wichtigen Gebiete der Mikrobiologie, von der Evolution uber den mikrobiellen Stoffwechsel und die technischen Anwendungen bis hin zum Gentransfer, zu den Endosymbionten und den Pathogenen werden abgedeckt. Auch wird den Archaea und den Viren entsprechend ihrer enormen Bedeutung ein eigener Teil gewidmet. Das Buch ist ein perfekter Begleiter fur die einfuhrende Vorlesung ?Allgemeine Mikrobiologie? sowie ein hervorragender Studienbegleiter fur alle Naturwissenschaftler und Ingenieure, die Mikrobiologie als Nebenfach belegen.
This comprehensive reference and handbook covers in depth all major aspects of the use of N-heterocyclic carbene-complexes in organic synthesis: from the theoretical background to characterization, and from cross-coupling reactions to olefin metathesis. Edited by a leader and experienced scientist in the field of homogeneous catalysis and use of NHCs, this is an essential tool for every academic and industrial synthetic chemist.
Bridge the gap between leadership development and career preparation! This guidebook gives leadership educators the tools they need to help students develop the competencies necessary for their chosen careers and required by their academic programs. It also offers a way to understand and demonstrate the effectiveness of leadership programs. Organized into chapters each focused on one of 60 leadership competencies common across 522 academic degree programs accredited by 97 agencies, each chapter covers: a definition and description of the competency through the lens of each of four dimensions: knowledge, value, ability, and behavior; a scenario related to college student leadership that showcases the competency in action; related competencies to help readers understand how developing one competency may also intentionally or unintentionally develop another; a correlation of the competency to the Relational Leadership Model, the Social Change Model, the Five Practices of Exemplary Leadership, and/or Emotionally Intelligent Leadership; and tangible curricular ideas to use with students to help them develop each dimension of the competency.
In this expert handbook both the topics and contributors are selected so as to provide an authoritative view of possible applications for this new technology. The result is an up-to-date survey of current challenges and opportunities in the design and operation of bioreactors for high-value products in the biomedical and chemical industries. Combining theory and practice, the authors explain such leading-edge technologies as single-use bioreactors, bioreactor simulators, and soft sensor monitoring, and discuss novel applications, such as stem cell production, process development, and multi-product reactors, using case studies from academia as well as from industry. A final section addresses the latest trends, including culture media design and systems biotechnology, which are expected to have an increasing impact on bioreactor design. With its focus on cutting-edge technologies and discussions of future developments, this handbook will remain an invaluable reference for many years to come.