Прочая образовательная литература
Различные книги в жанре Прочая образовательная литератураReliability in Biomechanics
In this book, the authors present in detail several recent methodologies and algorithms that we have developed during the last fifteen years. The deterministic methods account for uncertainties through empirical safety factors, which implies that the actual uncertainties in materials, geometry and loading are not truly considered. This problem becomes much more complicated when considering biomechanical applications where a number of uncertainties are encountered in the design of prosthesis systems. This book implements improved numerical strategies and algorithms that can be applied only in biomechanical studies.
Material Forming Processes. Simulation, Drawing, Hydroforming and Additive Manufacturing
Manufacturing industries strive to improve the quality and reliability of their products, while simultaneously reducing production costs. To do this, modernized work tools must be produced; this will enable a reduction in the duration of the product development cycle, optimization of product development procedures, and ultimately improvement in the productivity of design and manufacturing phases. Numerical simulations of forming processes are used to this end, and in this book various methods and models for forming processes (including stamping, hydroforming and additive manufacturing) are presented. The theoretical and numerical advances of these processes involving large deformation mechanics on the basis of large transformations are explored, in addition to the various techniques for optimization and calculation of reliability. The advances and techniques within this book will be of interest to professional engineers in the automotive, aerospace, defence and other industries, as well as graduates and undergraduates in these fields.
Biomechanics. Optimization, Uncertainties and Reliability
In this book, the authors present in detail several recent methodologies and algorithms that they developed during the last fifteen years. The deterministic methods account for uncertainties through empirical safety factors, which implies that the actual uncertainties in materials, geometry and loading are not truly considered. This problem becomes much more complicated when considering biomechanical applications where a number of uncertainties are encountered in the design of prosthesis systems. This book implements improved numerical strategies and algorithms that can be applied to biomechanical studies.
Organic Reactions, Volume 88
Volume 88 represents the tenth single-chapter-volume produced in our 73-year history. Such single-chapter volumes represent definitive treatises on extremely important chemical transformations. The success of the research efforts over the past 20 years forms the basis for the single chapter in this volume namely, Hydroamination of Alkenes by Alexander L. Reznichenko and Kai C. Hultzsch. The authors have compiled an enormous (and growing) literature and distilled it into an extraordinarily useful treatise on all aspects of the hydroamination process.
Organic Reactions, Volume 89
The latest volume in this series for organic chemists in industry presents critical discussions of widely used organic reactions or particular phases of a reaction. The material is treated from a preparative viewpoint, with emphasis on limitations, interfering influences, effects of structure and the selection of experimental techniques. The work includes tables that contain all possible examples of the reaction under consideration. Detailed procedures illustrate the significant modifications of each method.
The HPLC-MS Handbook for Practitioners
Filling the gap for an expert text dealing exclusively with the practical aspects of HPLC-MS coupling, this concise, compact, and clear book provides detailed information to enable users to employ the method most efficiently. Following an overview of the current state of HPLC-MS and its instrumentation, the text goes on to discuss all relevant aspects of method development. A chapter on tips and tricks is followed by user reports on the advantages – and pitfalls – of applying the method in real-life scenarios. The whole is rounded off by a look at future developments by renowned manufacturers.
Das HPLC-MS-Buch für Anwender
Aus einem Verfahren fur Spezialisten in der Forschung hat sich die LC/MS-Kopplung zu einer bewahrten Routineanwendung entwickelt. Ziel des Buchs ist, LC/MS-Anwendern moglichst detaillierte Informationen zu geben, damit sie ihre LC/MS-Applikation optimal durchfuhren konnen. Nach einem Uberblick uber den gegenwartigen Stand der Technik und instrumentelle Voraussetzungen werden Aspekte der Methodenentwicklung diskutiert. Ein Kapitel mit Tipps und Tricks leitet zu Anwenderberichte uber, bei denen auch ein Blick uber die klassische HPLC hinaus zur Ionenchromatographie geworfen wird. Berichte von renommierten Gerateherstellern uber neueste Entwicklungen runden das Buch ab. Dieses Praktikerbuch liefert LC/MS-Anwendern die Informationen, die sie zur optimalen Nutzung ihrer Gerate benotigen: Von instrumentellen Voraussetzungen und Methodenentwicklung bis zu Anwender- und Herstellerberichten werden wichtige Themen kompakt auf den Punkt gebracht.
Micro- and Nanosystems for Biotechnology
Emphasizing their emerging capabilities, this volume provides a strong foundation for an understanding of how micro- and nanotechnologies used in biomedical research have evolved from concepts to working platforms. Volume editor Christopher Love has assembled here a highly interdisciplinary group of authors with backgrounds ranging from chemical engineering right up to materials science to reflect how the intersection of ideas from biology with engineering disciplines has spurred on innovations. In fact, a number of the basic technologies described are reaching the market to advance the discovery and development of biopharmaceuticals. The first part of the book focuses on microsystems for single-cell analysis, examining tools and techniques used to isolate cells from a range of biological samples, while the second part is dedicated to tiny technologies for modulating biological systems at the scale of individual cells, tissues or whole organisms. New tools are described which have a great potential for (pre)clinical development of interventions in a range of illnesses, such as cancer and neurological diseases. Besides describing the promising applications, the authors also highlight the ongoing challenges and opportunities in the field.
Asymmetric Dearomatization Reactions
The first comprehensive account of the rapidly growing field of asymmetric dearomatization reactions with a focus on catalytic methods. It introduces the concept of dearomatization and describes recent progress in asymmetric reaction procedures with different catalyst systems, such as organocatalysts, transition metal catalysts, and enzymes. Chapters on dearomatizations of electron-deficient aromatic rings, dearomatization reactions via transition metal-catalyzed cross-couplings as well as dearomatization strategies in the synthesis of complex natural products are also included. Written by pioneers in the field, this is a highly valuable source of information not only for professional synthetic chemists in academia and industry but also for all those are interested in asymmetric methodologies and organic synthesis in general.
Gene Regulation, Epigenetics and Hormone Signaling
The first of its kind, this reference gives a comprehensive but concise introduction to epigenetics before covering the many interactions between hormone regulation and epigenetics at all levels. The contents are very well structured with no overlaps between chapters, and each one features supplementary material for use in presentations. Throughout, major emphasis is placed on pathological conditions, aiming at the many physiologists and developmental biologists who are familiar with the importance and mechanisms of hormone regulation but have a limited background in epigenetics.