Прочая образовательная литература
Различные книги в жанре Прочая образовательная литератураMetallofoldamers. Supramolecular Architectures from Helicates to Biomimetics
Metallofoldamers are oligomers that fold into three-dimensional structures in a controlled manner upon coordination with metal ions. Molecules in this class have shown an impressive ability to form single-handed helical structures and other three-dimensional architectures. Several metallofoldamers have been applied as sensors due to their selective folding when binding to a specific metal ion, while others show promise for applications as responsive materials on the basis of their ability to fold and unfold upon changes in the oxidation state of the coordinated metal ion, and as novel catalysts. Metallofoldamers: From Helicates to Biomimetic Architectures describes the variety of interactions between oligomers and metal species, with a focus on non-natural synthetic molecules. Topics covered include: the major classes of foldamers and their folding driving force metalloproteins and metalloenzymes helicates: self-assembly, structure and applications abiotic metallo-DNA metallo-PNA and iDNA metallopeptides interactions of biomimetic oligomers with metal ions applications of metallofoldamers
Practical Medicinal Chemistry with Macrocycles. Design, Synthesis, and Case Studies
Including case studies of macrocyclic marketed drugs and macrocycles in drug development, this book helps medicinal chemists deal with the synthetic and conceptual challenges of macrocycles in drug discovery efforts. • Provides needed background to build a program in macrocycle drug discovery –design criteria, macrocycle profiles, applications, and limitations • Features chapters contributed from leading international figures involved in macrocyclic drug discovery efforts • Covers design criteria, typical profile of current macrocycles, applications, and limitations
Circulating Tumor Cells. Isolation and Analysis
Introduces the reader to Circulating Tumor Cells (CTCs), their isolation method and analysis, and commercially available platforms Presents the historical perspective and the overview of the field of circulating tumor cells (CTCs) Discusses the state-of-art methods for CTC isolation, ranging from the macro- to micro-scale, from positive concentration to negative depletion, and from biological-property-enabled to physical-property-based approaches Details commercially available CTC platforms Describes post-isolation analysis and clinical translation Provides a glossary of scientific terms related to CTCs
Nanomagnetism. Applications and Perspectives
This first book to focus on the applications of nanomagnetism presents those already realized while also suggesting bold ideas for further breakthroughs. The first part is devoted to the concept of spin electronics and its use for data storage and magnetic sensing, while the second part concentrates on magnetic nanoparticles and their use in industrial environment, biological and medical applications. The third, more prospective part goes on to describe emerging applications related to spin current creation and manipulation, dynamics, spin waves and binary logic based on nano-scale magnetism. With its unique choice of topics and authors, this will appeal to academic as well as corporate researchers in a wide range of disciplines from physics via materials science to engineering, chemistry and life science.
Attosecond and XUV Spectroscopy. Ultrafast Dynamics and Spectroscopy
This book provides fundamental knowledge in the fields of attosecond science and free electron lasers, based on the insight that the further development of both disciplines can greatly benefit from mutual exposure and interaction between the two communities. With respect to the interaction of high intensity lasers with matter, it covers ultrafast lasers, high-harmonic generation, attosecond pulse generation and characterization. Other chapters review strong-field physics, free electron lasers and experimental instrumentation. Written in an easy accessible style, the book is aimed at graduate and postgraduate students so as to support the scientific training of early stage researchers in this emerging field. Special emphasis is placed on the practical approach of building experiments, allowing young researchers to develop a wide range of scientific skills in order to accelerate the development of spectroscopic techniques and their implementation in scientific experiments. The editors are managers of a research network devoted to the education of young scientists, and this book idea is based on a summer school organized by the ATTOFEL network.
Provisioning, Recovery, and In-Operation Planning in Elastic Optical Networks
Explains the importance of Elastic Optical Networks (EONs) and how they can be implemented by the world’s carriers This book discusses Elastic Optical Networks (EONs) from an operational perspective. It presents algorithms that are suitable for real-time operation and includes experimental results to further demonstrate the feasibility of the approaches discussed. It covers practical issues such as provisioning, protection, and defragmentation. It also presents provisioning and recovery in single layer elastic optical networks (EON). The authors review algorithms for provisioning point-to-point, anycast, and multicast connections, as well as transfer-based connections for datacenter interconnection. They also include algorithms for recovery connections from failures in the optical layer and in-operation planning algorithms for EONs. Provisioning, Recovery and In-operation Planning in Elastic Optical Network also examines multi-layer scenarios. It covers virtual network topology reconfiguration and multi-layer recovery, and includes provisioning customer virtual networks and the use of data analytics in order to bring cognition to the network. In addition, the book: Presents managing connections dynamically—and the flexibility to adapt the connection bitrate to the traffic needs fit well for new types of services, such as datacenter interconnection and Network Function Virtualization (NFV) Examines the topic in a holistic and comprehensive way, addressing control and management plane issues for provisioning, recovery, and in-operation planning Covers provisioning, recovery, and in-operation planning for EONs at the proposed exhaustive level The rapid expanse of new services has made the use of EONs (a relatively new concept) a necessity. That’s why this book is perfect for students and researchers in the field of technologies for optical networks (specifically EONs), including network architectures and planning, dynamic connection provisioning, on-line network re-optimization, and control and management planes. It is also an important text for engineers and practitioners working for telecom network operators, service providers, and vendors that require knowledge on a rapidly evolving topic.
Thermohydrodynamic Instability in Fluid-Film Bearings
Thermohydrodynamic Instability in Fluid-Film Bearings aims to establish instability criteria for a rotor-bearing system associated with fluid-film journal bearings. • It focuses on how the influencing factors such as rotor flexibility, manufacturing imperfections such as residual shaft unbalance, and service-related imperfections such as uneven wear affect the stability of a rotor-bearing system • It shows how the specific operating conditions such as oil inlet temperature, inlet pressure, and inlet position of a rotor-bearing system directly influence the system stability • General design guidelines have been summarized to guide the engineering system design and the correction of failure and/or malfunction
Fundamentals of Earthquake Engineering. From Source to Fragility
Fundamentals of Earthquake Engineering: From Source to Fragility, Second Edition combines aspects of engineering seismology, structural and geotechnical earthquake engineering to assemble the vital components required for a deep understanding of response of structures to earthquake ground motion, from the seismic source to the evaluation of actions and deformation required for design, and culminating with probabilistic fragility analysis that applies to individual as well as groups of buildings. Basic concepts for accounting for the effects of soil-structure interaction effects in seismic design and assessment are also provided in this second edition. The nature of earthquake risk assessment is inherently multi-disciplinary. Whereas this book addresses only structural safety assessment and design, the problem is cast in its appropriate context by relating structural damage states to societal consequences and expectations, through the fundamental response quantities of stiffness, strength and ductility. This new edition includes material on the nature of earthquake sources and mechanisms, various methods for the characterization of earthquake input motion, effects of soil-structure interaction, damage observed in reconnaissance missions, modeling of structures for the purposes of response simulation, definition of performance limit states, fragility relationships derivation, features and effects of underlying soil, structural and architectural systems for optimal seismic response, and action and deformation quantities suitable for design. Key features: Unified and novel approach: from source to fragility Clear conceptual framework for structural response analysis, earthquake input characterization, modelling of soil-structure interaction and derivation of fragility functions Theory and relevant practical applications are merged within each chapter Contains a new chapter on the derivation of fragility Accompanied by a website containing illustrative slides, problems with solutions and worked-through examples Fundamentals of Earthquake Engineering: From Source to Fragility, Second Edition is designed to support graduate teaching and learning, introduce practising structural and geotechnical engineers to earthquake analysis and design problems, as well as being a reference book for further studies.
Pain Genetics. Basic to Translational Science
Pain Genetics: Basic to Translational Science is a timely synthesis of the key areas of research informing our understanding of the genetic basis of pain. The book opens with foundational information on basic genetic mechanisms underlying pain perception and progresses recently discovered complex concepts facing the field. The coverage is wide-ranging and will serves as an excellent entry point into understating the genetics of pain as well as providing a single resource for established researchers looking for a better understanding of the diverse strands of research going on in the area. With contributors painstakingly selected to provide a broad range of perspectives and research, Pain Genetics will be a valuable resource for geneticists, neuroscientists, and biomedical professionals alike.
Advanced Molecularly Imprinting Materials
Molecularly imprinted polymers (MIPs) are an important functional material because of their potential implications in diverse research fields. The materials have been developed for a range of uses including separation, environmental, biomedical and sensor applications. In this book, the chapters are clustered into two main sections: Strategies to be employed when using the affinity materials, and rational design of MIPs for advanced applications. In the first part, the book covers the recent advances in producing MIPs for sample design, preparation and characterizations. In the second part, the chapters demonstrate the importance and novelty of creation of recognition imprinted on the materials and surfaces for a range of microbial detection sensors in the biomedical, environmental and food safety fields as well as sensing human odor and virus monitoring systems. Part 1: Strategies of affinity materials Molecularly imprinted polymers MIP nanomaterials Micro- and nanotraps for solid phase extraction Carbonaceous affinity nanomaterials Fluorescent MIPs MIP-based fiber optic sensors Part 2: Rational design of MIP for advanced applications MIP-based biomedical and environmental sensors Affinity adsorbents for environmental biotechnology MIP in food safety MIP-based virus monitoring MIP-based drug delivery and controlled release Biorecognition imprints on the biosensor surfaces MIP-based sensing of volatile organic compounds in human body odour MIP-based microcantilever sensor system