Медицина
Различные книги в жанре МедицинаLactogenic Hormones
The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.
Adrenergic Mechanisms
The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.
Insulin Resistance
Insulin resistance, defined as a reduced biological action of insulin, has emerged as a major factor in the development and progression of a number of common non-communicable diseases in man. The role of insulin resistance in the aetiology of type 2 diabetes is particularly well-established. However, insulin resistance has also come to be regarded as a key component of a broader syndrome of common metabolic defects that conspire to increase the risk of atherosclerotic coronary heart disease. The ramifications of insulin resistance now embrace many different medical specialties. The objective of this book is to summarize the current state of knowledge about insulin resistance. Section 1 (Pathophysiology of Insulin Resistance) considers the development of current concepts of insulin resistance. This is followed by a critical review of techniques for the assessment of insulin action in humans. The section concludes with an outline of current hypotheses concerning the molecular defects responsible for insulin resistance. Section 2 (Insulin Resistance in Clinical Medicine) broadens the discussion to include physiological and pathological conditions with which insulin resistance is associated; the effects of drug treatment on insulin sensitivity are also considered. Section 3 (Management of Insulin Resistance and Associated Conditions) focuses on the avoidance and treatment of insulin resistance in its clinical manifestations. A discussion of the potential benefits of non-pharmacological measures prefaces a review of the range of drugs used in the treatment of type 2 diabetes and related disorders. References are confined to key articles at the end of each section. Improved nutrition allied to increased levels of physical exercise are of crucial importance in the battle to stem the increasing incidence and prevalence of insulin resistance; however, translation of such advice into action has proved difficult in practice. Thus, other approaches have been explored. Recent years have witnessed considerable progress in the pharmacological management of insulin resistance. In particular, the thiazolidinediones (and other insulin-sensitizing drugs) appear to provide a more specific assault on insulin-resistance. Clinical experience with these agents remains relatively limited and serious hepatotoxicity has clouded the first agent in this class – troglitazone. With its introduction into the USA in 1995 and driven by the publication of the United Kingdom Prospective Diabetes Study, metformin has enjoyed a renaissance. This well-established agent is finding application for new clinical indications. In parallel, the development of anti-obesity drugs continues apace. The molecular and genetic mechanisms underlying some forms of insulin resistance are being revealed. Original intellectual concepts such as the fetal origins hypothesis are challenging traditional views about the aetiology of insulin resistance and its clinical sequelae. These exciting scientific advances notwithstanding, the evolving global epidemic of obesity and type 2 diabetes represents an enormous public health challenge. Now more than ever, research must focus on identifying solutions that are applicable on the level of entire populations. By definition, these must also be practical and cost-effective.
Insulin Resistance
Diabetes is now one of the major causes of morbidity worldwide. In many cases, the onset of diabetes is progressive, developing via a condition of insulin resistance. This book considers the development of this condition, its consequences and clinical and therapeutic aspects. The book reviews the normal biology of insulin action on glucose, lipids and proteins. It considers the pathological basis for insulin resistance in animal models and humans, and discusses the influence of heredity, dietary factors and exercise. Clinical consequences including dyslipidaemia, hypertension and polycystic ovary syndrome, and therapeutic strategies for treatment are also examined. * Provides an expert review of the phenomenon of insulin resistance * Brings together a host of recent research for the first time * Written by leading experts in biological and clinical research
Emergency Triage
The Manchester Triage System (MTS) is the most widely used triage system in the UK, Europe and Australia, with tens of millions of patients being processed through hospital emergency departments. Emergency Triage is the core text for the MTS which utilises a risk averse system of prioritisation for patients in all unscheduled care settings, and as such it is an essential text for all emergency department staff using the MTS, in particular triage nurses themselves. The second edition has been revised throughout and takes in the changes in practice introduced into MTS since the book was first published. These include: Redesigned and expanded flow charts Additional charts for allergy and palpitations New practices – such as the possibility of revascularisation for patients with stroke New discriminators, for example acute neurological deficit and significant respiratory history Redefinition of existing discriminators Also new to this edition is the incorporation of sections on the use of the risk averse system in telephone triage, in settings where ‘streaming’ takes place and as an early warning score for patients in all unscheduled care settings. The tone of this edition reflects the more up to date, modified approach to triage while retaining the principles of clinical prioritisation, which in the authors’ words “remains a central plank of clinical risk management in emergency care”. Emergency Triage is an essential handbook for all clinicians involved in unscheduled care settings such as emergency care, walk in centres, minor injury units, primary care out of hours services.
Emergency Medicine
Emergency Medicine is a brand new book focusing on the common pitfalls and mistakes that can occur when dealing with high-risk conditions during standard medical practice. Concise chapters focus on clinical relevance, addressing the mistakes, the consequences and the knowledge necessary to avoid high-risk mistakes. An essential book for all staff dealing with emergencies.
Infectious Disease
“… a fun and readable book that engages the imagination and retains the interest of the clinically oriented reader while conveying an understanding of the direct implications of molecular characteristics of infectious agents to the practice of medicine..” –Emerging Infectious Diseases, January 2010 “… provides a valuable overview of the basic principles and issues pertaining to the pathogenesis and prevention of infectious diseases. The illustrations, the chapter summaries with relevant information, and the case studies are all particularly useful for the targeted readers. The book is well designed and manages to convey the general concepts of the various aspects of infectious diseases without overwhelming the reader with too much information… recommended for students, trainees, or physicians who desire a well-illustrated textbook that is easy to read and that addresses the basic aspects of infectious disease.” –Clinical Infectious Diseases, 2010 The study of infectious diseases has undergone major changes since its infancy when it was largely a documentation of epidemics. It has now evolved into a dynamic phenomenon involving the ecology of the infectious agent, pathogenesis in the host, reservoirs and vetors, as well as the complex mechanisms concerned in the spread of infection and the extent to which this spread occurs. Rapid globalization has led to unprecedented interest in infectious diseases worldwide and their effect on complex population dynamics including migration, famine, fire, war, and terrorism. It is now essential for public health officials to understand the basic science behind infectious disease and, likewise, students studying ID must have a broader understanding of the implications of infectious disease in a public health context as well as clinical presentation and prevention. The clear demand for an integrated approach has led to the publication of this text. Check out the student companion site at www.wiley.com/go/shettyinfectiousdisease
Fungal Infection
Concise, up-to-date guide to the clinical manifestations, laboratory diagnosis and management of superficial, subcutaneous and systemic fungal infections «I would recommend this book to all microbiologists and clinicians regularly dealing with patients suffering from fungal infections.» Journal of Medical Microbiology WHY BUY THIS BOOK? Thorough update of significant developments in the diagnosis and management of fungal infections Up-to-date drug and dosage recommendations updated in line with current guidelines New feature: epidemiology and prevention section in each chapter plus further reading lists of key papers New feature: algorithms in each section on management and treatment of key fungal infections Problem-orientated to help clinician make best use of time-consuming laboratory investigations This title is now available for the PDA, powered by Skyscape – to buy your copy click here
Experimental Tuberculosis
The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.
Laser Dermatology
The first all-inclusive text on the pitfalls, complications and controversies surrounding the use of lasers in dermatology and aesthetic medicine Each chapter starts off by highlighting the key points and essential concepts, followed by a review of the associated pearls and problems Provides the reader with tips on how to improve the safe and effective use of lasers Images focus on the pearls and problems Laser Dermatology: Pearls and Problems is different from other laser dermatology books. Each of the five chapters begins by highlighting key points and essential concepts, then focuses on the pearls and problems for each area – based on the author’s vast experience in the field of laser dermatology. Dr. Goldberg addresses: Vascular Lasers Laser Hair Removal Pigmented Lesions, Tattoos, and Disorders of Hypopigmentation Ablative Lasers and Devices Non-Ablative Photorejuvenation and Skin Remodeling Dr. Goldberg goes beyond the standard “before and after” approach to use actual images to demonstrate the pearls and pitfalls discussed in the text.