Медицина
Различные книги в жанре МедицинаPeptide Drug Discovery and Development. Translational Research in Academia and Industry
Filling a real knowledge gap, this handbook and ready reference is both modern and forward-looking in its emphasis on the «bench to bedside» translational approach to drug development. Clearly structured into three major parts, the book stakes out the boundaries of peptide drug development in the preclinical as well as clinical stages. The first part provides a general background and focuses on the characteristic strengths and weaknesses of peptide drugs. The second section contains five cases studies of peptides from diverse therapeutic fields, and the lessons to be learned from them, while the final part looks at new targets and opportunities, discussing several drug targets and diseases for which peptide drugs are currently being developed.
An Atlas of Interpretative Radiographic Anatomy of the Dog and Cat
This is the definitive reference for the small animal practitioner to normal radiographic anatomy of the cat and dog. With over forty years of experience between them, the authors have produced an invaluable reference atlas for the veterinary practitioner. The book is suitable for the general and referral based practitioner, undergraduate or postgraduate veterinary surgeon. Over 550 radiographic images analysed and explained More than 50 new figures added, with the quality of existing images enhanced Revised contents and page headers for easy-reference Clear informative line drawings to trace radiographic shadows and schematic drawings of underlying structures not seen in plain radiographs.
Pharmaceutical Lifecycle Management. Making the Most of Each and Every Brand
A comprehensive guide to optimizing the lifecycle management of pharmaceutical brands The mounting challenges posed by cost containment policies and the prevalence of generic alternatives make optimizing the lifecycle management (LCM) of brand drugs essential for pharmaceutical companies looking to maximize the value of their products. Demonstrating how different measures can be combined to create winning strategies, Pharmaceutical Lifecycle Management: Making the Most of Each and Every Brand explores this increasingly important field to help readers understand what they can—and must—do to get the most out of their brands. Offering a truly immersive introduction to LCM options for pharmaceuticals, the book incorporates numerous real-life case studies that demonstrate successful and failed lifecycle management initiatives, explaining the key takeaway of each example. Filled with practical information on the process of actually writing and presenting an LCM plan, as well as how to link corporate, portfolio, and individual brand strategies, the book also offers a look ahead to predict which LCM strategies will continue to be effective in the future. While the development of new drugs designed to address unmet patient needs remains the single most important goal of any pharmaceutical company, effective LCM is invaluable for getting the greatest possible value from existing brands. Pharmaceutical Lifecycle Management walks you through the process step by step, making it indispensable reading for pharmaceutical executives and managers, as well as anyone working in the fields of drug research, development, and regulation.
Vascular and Endovascular Surgery at a Glance
Following the popular and accessible at a Glance format, Vascular and Endovascular Surgery at a Glance demystifies the important concepts of vascular disease and vascular surgery. Featuring in-depth details of common vascular topics, to rarer presentations, this is an ideal guide for those interested in a variety of subjects relating to this rapidly expanding area. This is a must-read for any specialist at all levels who has an on-going commitment to vascular disease management and medical education. Vascular and Endovascular Surgery at a Glance: • Comprehensively covers the key concepts and core practical procedures with superb illustrations • Is a brilliant companion to the emerging curriculum for specialist vascular training • Is an excellent source of information and management guidelines for interdisciplinary specialties • Includes a companion website at www.ataglanceseries.com/vascular featuring a wide range of interactive multiple choice questions This title forms a succinct overview of vascular disease management, giving salient points relevant to general surgery examinations, for those requiring an in-depth yet manageable introduction to vascular diseases, and for those entering this prevalent field as a stand-alone specialty.
Case Studies in Gerontological Nursing for the Advanced Practice Nurse
As the fastest growing population sector worldwide, older adults are seen in almost every care setting in which clinicians practice. Developed as a resource for advanced practice nurses in any setting, Case Studies in Gerontological Nursing for the Advanced Practice Nurse presents readers with a range of both typical and atypical cases from real clinical scenarios. The book is organized into six units covering cases related to ageism, common health challenges, health promotion, environments of care, cognitive and psychological issues, and issues relating to aging and independence. Each case follows a similar format including the patient's presentation, critical thinking questions, and a thorough discussion of the case resolution through which students and clinicians can enhance their clinical reasoning skills. Designed to promote geriatric clinical education through self-assessment or classroom use, Case Studies in Gerontological Nursing for the Advanced Practice Nurse is a key resource for all those dedicated to improving care for older adults.
General Hospital Care for People with Learning Disabilities
General Hospital Care for People with Learning Disabilities is a comprehensive resource for those health professionals in a general hospital setting who may come into contact with people with learning disabilities. The book explores the nature of learning disabilities and highlights specific healthcare needs. It takes the reader through all the key factors in the healthcare process, through pre-admission assessment, care planning, intervention and treatment, and liaison and discharge planning, while highlighting key healthcare needs at each stage. The Department of Health, the National Health Service Executive and Mencap have all reported that people with learning disabilities have increased health needs compared to the general population, yet these needs are often poorly met and people experience difficulties in accessing appropriate services. This is a timely and accessible resource for healthcare professionals in need of a general introduction to caring for people with a learning disability. Relevant to the care of both children and adults with a learning disability Use of case studies to illustrate examples of situations explored in the main text Focuses on key areas of communication, understanding behavior and the often difficult area of consent
How to Succeed at Medical School. An Essential Guide to Learning
Can you adapt to the wide variety of learning environments in medicine? Can you show your best abilities in the exams at the same time as learning to be a doctor? Can you balance your studies with an enjoyable social life? Can you develop your professionalism and manage your 'digital footprint'? How to Succeed at Medical School will help you learn these vital skills, and much more. Written by experienced medical school teachers and packed full of case studies, illustrations, quotes from other students, tip boxes, exercises, portfolios and learning techniques to help you communicate, study and revise – it’s an essential resource to help you thrive at medical school. This thoroughly updated second edition includes new chapters on Professionalism and Teaching, and provides invaluable insight into what to expect from the start of medical school right through to the start of your medical career.
Pharmaceutical Toxicology in Practice. A Guide to Non-clinical Development
This book describes, with references to key source materials, the background to, and conduct of, the principal nonclinical studies that are central to drug development. The chapters provide an understanding of the key components of the preclinical phase of drug development with a hands-on description, with core chapters addressing study conduct, types, and reporting. As such, it is a practical guide through toxicology testing and an up-to-date reference on current issues, new developments, and future directions in toxicology. Opening with a practical description of toxicology and its role in the development of pharmaceuticals, the book proceeds to detail international regulations (including the impact of the new REACH standards for chemical safety), interdisciplinary interactions among scientists in drug development, steps in toxicity testing, and risk management. Further, the book covers the methods of genetic toxicology (assays, genomics, in vivo screening) as a complement to “traditional” toxicology in the risk assessment and risk management of pharmaceuticals.
Pharmacotherapy of Child and Adolescent Psychiatric Disorders
This book fulfils an urgent need for an updated text on pediatric psychopharmacology. It takes a unique approach in discussing recent findings within the context of current issues, including economic and political ones. The book covers the emerging question of treating children who do not yet meet diagnostic criteria for psychosis, e.g, schizophrenia or bipolar disorder, but who are deemed to be at high risk. This is an active area of debate: such children are being treated in certain centers, while others reject this completely. The book addresses the antidepressant controversy, the placebo response and unique strategies for delineating this, and ways to optimize the differential between active medication and placebo. It reviews the impact of recent American Heart Association guidelines for monitoring children on stimulants and other psychotropics. It adheres closely to DSM-IV diagnostic criteria throughout. The book describes the use of newly approved drugs such as Lexapro for treating adolescent depression and the novel compound Intuniv. It covers the TADS and CAMS studies, which evaluated the use of SSRIs alone and in combination with cognitive behavioral therapy for adolescent depression. Other topics include treatment of bipolar disorders, the increasing popularity of generic equivalents, combination pharmacotherapy and the potential dangers of psychotropic medications. Third edition of the first ever book published on pediatric psychopharmacology from renowned editors. Incorporates current developments with regard to SSRIs, their indications and their safety issues, including possible associated suicidal behavior. Addresses concerns about cardiovascular side effects of the new stimulant medications available, and compares to other FDA-approved medications for ADHD. Features many tables, figures and pictorials, making it highly accessible and reader friendly.
Clinical Data Interpretation for Medical Finals. Single Best Answer Questions
Written by senior clinicians across a range of specialties, Data Interpretation for Medical Finals: Single Best Answer Questions is the perfect way to prepare for data interpretation assessments and clinical practice. Featuring over 200 questions on key topics in medicine, each question is set around an image or investigation, such as an X-ray, CT scan, or blood film, and tests identification and interpretation of the data provided. Thorough explanation of the correct and incorrect answers helps you learn from mistakes. The questions reflect current exam question style and incorporate high quality images, many of which are annotated, and are presented in full colour throughout. Data Interpretation for Medical Finals will help build the confidence of all medical students, and Foundation Doctors, as it encourages application of investigation results to clinical decision making.