Kinomics. Approaches and Applications. Heinz-Bernhard Kraatz
Прочая образовательная литература.
Kinomics. Approaches and Applications
Год выпуска 0
isbn 9783527683048
Автор произведения Heinz-Bernhard Kraatz
Жанр Прочая образовательная литература
Издательство John Wiley & Sons Limited
Authored by the world's leading kinase experts, this is a comprehensive introduction to current knowledge and practice within this emerging field. Following an overview of the major players and pathways that define the kinome, the major part of this work is devoted to current strategies of kinome investigation and manipulation. As such, kinase engineering, peptide substrate engineering, co-substrate design and kinase inhibitor design are discussed in detail, and their potential applications in kinome analysis and kinome-based pharmacotherapy are shown. The result is a toolbox for every kinase researcher: By addressing and comparing current approaches to the study of kinase action, both novice and established researchers will benefit from the practical knowledge contained in this invaluable reference.