John Wiley & Sons Limited
Все книги издательства John Wiley & Sons LimitedComputer Aided Design and Manufacturing
Broad coverage of digital product creation, from design to manufacture and process optimization This book addresses the need to provide up-to-date coverage of current CAD/CAM usage and implementation. It covers, in one source, the entire design-to-manufacture process, reflecting the industry trend to further integrate CAD and CAM into a single, unified process. It also updates the computer aided design theory and methods in modern manufacturing systems and examines the most advanced computer-aided tools used in digital manufacturing. Computer Aided Design and Manufacturing consists of three parts. The first part on Computer Aided Design (CAD) offers the chapters on Geometric Modelling; Knowledge Based Engineering; Platforming Technology; Reverse Engineering; and Motion Simulation. The second part on Computer Aided Manufacturing (CAM) covers Group Technology and Cellular Manufacturing; Computer Aided Fixture Design; Computer Aided Manufacturing; Simulation of Manufacturing Processes; and Computer Aided Design of Tools, Dies and Molds (TDM). The final part includes the chapters on Digital Manufacturing; Additive Manufacturing; and Design for Sustainability. The book is also featured for being uniquely structured to classify and align engineering disciplines and computer aided technologies from the perspective of the design needs in whole product life cycles, utilizing a comprehensive Solidworks package (add-ins, toolbox, and library) to showcase the most critical functionalities of modern computer aided tools, and presenting real-world design projects and case studies so that readers can gain CAD and CAM problem-solving skills upon the CAD/CAM theory. Computer Aided Design and Manufacturing is an ideal textbook for undergraduate and graduate students in mechanical engineering, manufacturing engineering, and industrial engineering. It can also be used as a technical reference for researchers and engineers in mechanical and manufacturing engineering or computer-aided technologies.
The Power of Plagues
The Power of Plagues presents a rogues' gallery of epidemic- causing microorganisms placed in the context of world history. Author Irwin W. Sherman introduces the microbes that caused these epidemics and the people who sought (and still seek) to understand how diseases and epidemics are managed. What makes this book especially fascinating are the many threads that Sherman weaves together as he explains how plagues past and present have shaped the outcome of wars and altered the course of medicine, religion, education, feudalism, and science. Cholera gave birth to the field of epidemiology. The bubonic plague epidemic that began in 1346 led to the formation of universities in cities far from the major centers of learning (and hot spots of the Black Death) at that time. And the Anopheles mosquito and malaria aided General George Washington during the American Revolution. Sadly, when microbes have inflicted death and suffering, people have sometimes responded by invoking discrimination, scapegoating, and quarantine, often unfairly, against races or classes of people presumed to be the cause of the epidemic. Pathogens are not the only stars of this book. Many scientists and physicians who toiled to understand, treat, and prevent these plagues are also featured. Sherman tells engaging tales of the development of vaccines, anesthesia, antiseptics, and antibiotics. This arsenal has dramatically reduced the suffering and death caused by infectious diseases, but these plague protectors are imperfect, due to their side effects or attenuation and because microbes almost invariably develop resistance to antimicrobial drugs. The Power of Plagues provides a sobering reminder that plagues are not a thing of the past. Along with the persistence of tuberculosis, malaria, river blindness, and AIDS, emerging and remerging epidemics continue to confound global and national public health efforts. West Nile virus, Lyme disease, and Ebola and Zika viruses are just some of the newest rogues to plague humans. The argument that civilization has been shaped to a significant degree by the power of plagues is compelling, and The Power of Plagues makes the case in an engaging and informative way that will be satisfying to scientists and non-scientists alike.
Structure and Function of the Bacterial Genome
Presents an integrated view of the expression of bacterial genetic information, genome architecture and function, and bacterial physiology and pathogenesis This book blends information from the very latest research on bacterial chromosome and nucleoid architecture, whole-genome analysis, cell signaling, and gene expression control with well-known gene regulation paradigms from model organisms (including pathogens) to give readers a picture of how information flows from the environment to the gene, modulating its expression and influencing the competitive fitness of the microbe. Structure and Function of the Bacterial Genome explores the governance of the expression of the genes that make a bacterium what it is, and updates the basics of gene expression control with information about transcription promoter structure and function, the role of DNA as a regulatory factor (in addition to its role as a carrier of genetic information), small RNAs, RNAs that sense chemical signals, ribosomes and translation, posttranslational modification of proteins, and protein secretion. It looks at the forces driving the conservation and the evolution of the dynamic genome and offers chapters that cover DNA replication, DNA repair, plasmid biology, recombination, transposition, the roles of repetitive DNA sequences, horizontal gene transfer, the defense of the genome by CRISPR-Cas, restriction enzymes, Argonaute proteins and BREX systems. The book finishes with a chapter that gives an integrated overview of genome structure and function. Blends knowledge of gene regulatory mechanisms with a consideration of nucleoid structure and dynamics Offers a 'DNA-centric' approach to considering transcription control Views horizontal gene transfer from a gene regulation perspective Assesses the opportunities and limitations of designing synthetic microbes or rewiring existing ones Structure and Function of the Bacterial Genome is an ideal book for graduate and undergraduate students studying microbial cell biology, bacterial pathogenesis, gene regulation, and molecular microbiology. It will also appeal to principal investigators conducting research on these and related topics and researchers in synthetic biology and other arms of biotechnology.
Pocket Guide to Clinical Microbiology
Quick reference to clinical microbiology If you work in the clinical laboratory, this pocket guide will help you confidently identify most organisms you could encounter. This useful updated edition continues to present valuable quick-reference information to the clinical microbiology community in a small package. Along with specifics on pathogenic microorganisms, there is updated information on effectively using essential molecular diagnostic techniques for today's challenges. You will find guidance on: MALDI-TOF MS performance for individual bacteria, mycobacteria, and fungi Nucleic acid amplification testing/PCR and help interpreting genetic sequencing results Susceptibility testing, with methods and interpretive criteria for most organism/antibiotic combinations Antimicrobial resistance mechanisms and resistance profiles for common organisms
Open and Toroidal Electrophoresis
Presents the theory and applications of Toroidal Capillary, Microchip, and Slab Electrophoresis to analytical chemists across a range of disciplines Written by one of the developers of Toroidal Capillary Electrophoresis (TCE), this book is the first to present this novel analytical technique, in detail, to the field of analytical chemistry. The exact expressions of separation efficiency, resolution, peak capacity, and many other performance indicators of the open and toroidal layouts are presented and compared. Featuring numerous illustrations throughout, Open and Toroidal Electrophoresis: Ultra-High Separation Efficiencies in Capillaries, Microchips and Slabs offers chapters covering: Solvents and Buffer Solutions; Fundamentals of Electrophoresis; Open Layout; and Toroidal Layout. Confronting Performance Indicators is next, followed by chapters on High Voltage Modules and Distributors; Heat Removal and Temperature Control; and Detectors. The book finishes with an examination of the applications of Toroidal Electrophoresis. The first book to offer a detailed account of Toroidal Electrophoresis—written by one of its creators Compares the toroidal layouts with the well-established open layouts of the three most used platforms (Capillary, Microchip, and Slab) Provides solutions to many of the experimental issues arising in electromigration techniques and discusses the voltage distributors and detectors that are compatible with the toroidal layouts Richly illustrated with a large number of useful equations showing the relationships between important operational parameters and the performance indicators Open and Toroidal Electrophoresis is aimed at method developers and separation scientists working in clinical analysis, and food analysis, as well as those in pharmacology, disease biomarker applications, and nucleic acid analysis using the Capillary, Microchip, or slab Platform. It will also benefit undergraduate and graduate students of inorganic analytical chemistry, organic analytical chemistry, bioanalysis, pharmaceutical sciences, clinical sciences, and food analysis.
Social Movements
A new, fully-revised and updated edition of the leading introduction to social movements and collective action – covers a broad range of approaches in the social sciences. Now in its third edition, Social Movements is the market-leading introductory text on collective action in contemporary society. The text draws from theory-driven, systematic empirical research from across the social sciences to address central questions and concepts in the field. Sophisticated yet reader-friendly chapters offer critical analyses of relevant literature whilst exploring important issues and debates. The global political landscape has undergone significant changes in the years since this book’s initial publication, such as the spread of online protests, the resurgence of nationalist and right-wing activity, global revolts, and increased social and economic polarization. This thoroughly updated edition offers fresh discussions of recent social movements against austerity from around the world, new empirical examples, references to recent episodes of contention, an expanded comparative approach to social movement theory in the scientific literature, and more. Positioned at the intersection of sociology and political science, this book: Presents an empirical and engaging exploration of contemporary social movements Discusses topics such as organizing within social movements, eventful protests, political opportunities, symbolism and identity in collective action, and social change Highlights how core mechanisms of collective action operate in different movements, past and present Provides a conceptual methodology useful for social science students and researchers alike Highlights how core mechanisms of collective action operate in different movements in the past and present Written by two internationally recognized experts in sociology and political science, the third edition of Social Movements: An Introduction is an essential course text and a must-read for students and scholars of sociology, political sociology, political science, and social movement studies.
Twelve Diseases that Changed Our World
Covers the history of twelve important diseases and addresses public health responses and societal upheavals. Chronicles the ways disease outbreaks shaped traditions and institutions of Western civilization. Explains the effects, causes, and outcomes from past epidemics. Describes a dozen diseases to show how disease control either was achieved or failed. Makes clear the interrelationship between diseases and history. Presents material in a compelling, clear, and jargon-free prose for a wide audience. Provides a picture of the best practices for dealing with disease outbreaks.
Forgotten People, Forgotten Diseases
Forgotten People, Forgotten Diseases Second Edition The neglected tropical diseases (NTDs) are the most common infections of the world's poor, but few people know about these diseases and why they are so important. This second edition of Forgotten People, Forgotten Diseases provides an overview of the NTDs and how they devastate the poor, essentially trapping them in a vicious cycle of extreme poverty by preventing them from working or attaining their full intellectual and cognitive development. Author Peter J. Hotez highlights a new opportunity to control and perhaps eliminate these ancient scourges, through alliances between nongovernmental development organizations and private-public partnerships to create a successful environment for mass drug administration and product development activities. Forgotten People, Forgotten Diseases also Addresses the myriad changes that have occurred in the field since the previous edition. Describes how NTDs have affected impoverished populations for centuries, changing world history. Considers the future impact of alliances between nongovernmental development organizations and private-public partnerships. Forgotten People, Forgotten Diseases is an essential resource for anyone seeking a roadmap to coordinate global advocacy and mobilization of resources to combat NTDs.
Practical Guide to Diagnostic Parasitology
An essential training aid and reference guide for laboratorians. Includes easy-to-follow collection and ordering guidelines and diagnostic techniques. Offers extensive discussion and a table to assist physicians with ordering the most appropriate diagnostic tests. Provides extensive information on method selection, clinical relevance, and test menus. Features diagnostic algorithms, summary tables, and identification keys. Presents comprehensive organism information on facing pages. Includes «how-to» tips based on 30 years of the author's benchwork experience Serves as a resource for microbiologists, physicians, medical technologists, public health personnel, teachers, and students.
Bioinorganic Chemistry
Introduces students to the basics of bioinorganic chemistry This book provides the fundamentals for inorganic chemistry and biochemistry relevant to understanding bioinorganic topics. It provides essential background material, followed by detailed information on selected topics, to give readers the background, tools, and skills they need to research and study bioinorganic topics of interest to them. To reflect current practices and needs, instrumental methods and techniques are referred to and mixed in throughout the book. Bioinorganic Chemistry: A Short Course, Third Edition begins with a chapter on Inorganic Chemistry and Biochemistry Essentials. It then continues with chapters on: Computer Hardware, Software, and Computational Chemistry Methods; Important Metal Centers in Proteins; Myoglobins, Hemoglobins, Superoxide Dismutases, Nitrogenases, Hydrogenases, Carbonic Anhydrases, and Nitrogen Cycle Enzymes. The book concludes with chapters on Nanobioinorganic Chemistry and Metals in Medicine. Readers are also offered end-of-section summaries, conclusions, and thought problems. Reduces size of the text from previous edition to match the first, keeping it appropriate for a one-semester course Offers primers and background materials to help students feel comfortable with research-level bioinorganic chemistry Emphasizes select and diverse topics using extensive references from current scientific literature, with more emphasis on molecular biology in the biochemistry section, leading to a discussion of CRISPR technology Adds new chapters on hydrogenases, carbonic anhydrases, and nitrogen cycle enzymes, along with a separate chapter on nanobioinorganic chemistry Features expanded coverage of computer hardware and software, metalloenzymes, and metals in medicines Supplemented with a companion website for students and instructors featuring Powerpoint and JPEG figures and tables, arranged by chapter Appropriate for one-semester bioinorganic chemistry courses, Bioinorganic Chemistry: A Short Course, Third Edition is ideal for upper-level undergraduate and beginning graduate students. It is also a valuable reference for practitioners and researchers in need of a general introduction to the subject, as well as chemists requiring an accessible reference.