John Wiley & Sons Limited
Все книги издательства John Wiley & Sons LimitedClinical Trials Audit Preparation. A Guide for Good Clinical Practice (GCP) Inspections
A must-have guide for any professional in the drug manufacturing industry The Good Clinical Practice (GCP) audit is a tedious but necessary exercise that assures that all parties do their job properly and in compliance with the applicable FDA code. Clinical Trials Audit Preparation demystifies the audit process for all parties involved, including clinical research sponsors, clinical investigators, and institutional review boards. This book provides a step-by-step explanation of the FDA audit procedures for clinical trials and of how pharmaceutical companies, clinical investigators, and institutional review boards should prepare for regulatory audits. The book emphasizes the processes and procedures that should be implemented before a clinical audit occurs, making this an imperative guide to any professional in the drug manufacturing industry, including drug manufacturing companies, regulatory affairs personnel, clinical investigators, and quality assurance professionals. Among the topics discussed: Good Clinical Practices and therapeutic product development in clinical research The roles of the sponsor of a clinical investigation, the IRB, or independent ethics committee The roles and responsibilities of the clinical trial investigator The inspection preparation The Audit Report and the Form 483 Warning letters issued to clinical investigators and clinical trial sponsors and their impact on product development
Wildlife Search and Rescue. A Guide for First Responders
Rescuing wild animals in distress requires a unique set of skills, very different from those used in handling domestic animals. The equipment, degree of handling, the type of caging and level of care a wild animal receives can mean the difference between life and death. Wildlife Search and Rescue is a comprehensive guide on ‘best practices’ and suggested standards for response to sick, injured and orphaned wildlife. This valuable resource covers the fundamentals of wildlife rescue, from ‘phone to field’, including safe and successful capture strategies, handling and restraint techniques and initial aid. Wildlife Search and Rescue is a must have for anyone interested in knowing what to do when they are face to face with a wild animal in need, or for anyone involved in animal rescue. While the book focuses on wildlife native to North America, much of the information and many of the techniques are applicable to other species, including domestic dogs and cats. Visit www.wiley.com/go/dmytryk/wildlifeemergency to access the figures from the book.
Life Cycle Assessment Handbook. A Guide for Environmentally Sustainable Products
The first book of its kind, the LCA Handbook will become an invaluable resource for environmentally progressive manufacturers and suppliers, product and process designers, executives and managers, and government officials who want to learn about this essential component of environmental sustainability.
Computational Drug Design. A Guide for Computational and Medicinal Chemists
Helps you choose the right computational tools and techniques to meet your drug design goals Computational Drug Design covers all of the major computational drug design techniques in use today, focusing on the process that pharmaceutical chemists employ to design a new drug molecule. The discussions of which computational tools to use and when and how to use them are all based on typical pharmaceutical industry drug design processes. Following an introduction, the book is divided into three parts: Part One, The Drug Design Process, sets forth a variety of design processes suitable for a number of different drug development scenarios and drug targets. The author demonstrates how computational techniques are typically used during the design process, helping readers choose the best computational tools to meet their goals. Part Two, Computational Tools and Techniques, offers a series of chapters, each one dedicated to a single computational technique. Readers discover the strengths and weaknesses of each technique. Moreover, the book tabulates comparative accuracy studies, giving readers an unbiased comparison of all the available techniques. Part Three, Related Topics, addresses new, emerging, and complementary technologies, including bioinformatics, simulations at the cellular and organ level, synthesis route prediction, proteomics, and prodrug approaches. The book's accompanying CD-ROM, a special feature, offers graphics of the molecular structures and dynamic reactions discussed in the book as well as demos from computational drug design software companies. Computational Drug Design is ideal for both students and professionals in drug design, helping them choose and take full advantage of the best computational tools available. Note: CD-ROM/DVD and other supplementary materials are not included as part of eBook file.
Net Zero Energy Design. A Guide for Commercial Architecture
Conveniently organized and packed with robust technical content and clear explanations of key principles Written by an architect who is the director of sustainability at a global architecture firm, Net Zero Energy Design is a practical guide for architects and related construction professionals who want to design and build net zero energy commercial architecture. It offers no-nonsense strategies, step-by-step technical analysis, and valuable examples, in addition to developed case studies. With a focus on application in a variety of building types and scales, the book also develops a broad-based understanding of all the integrated principles involved in achieving net zero energy. This book is an indispensable resource for anyone venturing into net zero energy design, construction, and operation, and it also serves as an excellent resource on a variety of sustainable design topics. Important features include: Organization based upon the commercial building delivery process Robust technical content for use in actual project applications Analysis examples that demonstrate key technical principles Plenty of design data for use as a valuable design resource Abundant and sophisticated information graphics and color illustrations and photographs A distinct design focus on the content that inspires adoption of principles into projects
Recovery from Eating Disorders. A Guide for Clinicians and Their Clients
With a uniquely perspective on the key factors in recovery from eating disorders, this practical guide for patients and clinicians draws from relevant, real-life case studies. Focuses on real-life recovery strategies that involve motivational factors, physical and psychological health, and issues such as self-esteem, body attitude, emotion regulation and social relationships. Draws on extensive qualitative research with more than 80 former sufferers Offers experience-based guidance for professionals assisting clients in their recovery process
Personal Health Records. A Guide for Clinicians
Patient-controlled personal health records are the key to successful interaction between physician and patient. They form the core for joined-up communication throughout health organizations. Still, the very name is capable of alarming both patient and doctor. Are they reliable? Are they complete? Are they confidential? Where do you access them? For the doctor, additional concerns surround the implementation: how do you include these online tools in your busy schedule? How much will they add to your existing spend on information technology? Can you get paid for doing all this extra work? Now you can find dependable answers to all of these questions. Written by a physician who has developed his own personal health records software for patients and doctors to interact, Personal Health Records: A Guide for Clinicians explains how to get the best from your patient's records and how to put the information to good use, helping both your patient and yourself to a more effective and efficient outcome in any clinical situation. “The author is a clinical academic, patient and pioneer in his field and does a grand job of explaining the ins and outs of PHRs in a non-patronising manner for the non-tech savvy” – From a review published in Health Services Journal by: Dr Emma Stanton, Commonwealth Fund Harkness Fellow and Specialist Registrar at South London and Maudsley NHS Foundation Trust
Design of Buildings for Wind. A Guide for ASCE 7-10 Standard Users and Designers of Special Structures
ASCE 7 is the US standard for identifying minimum design loads for buildings and other structures. ASCE 7 covers many load types, of which wind is one. The purpose of this book is to provide structural and architectural engineers with the practical state-of-the-art knowledge and tools needed for designing and retrofitting buildings for wind loads. The book will also cover wind-induced loss estimation. This new edition include a guide to the thoroughly revised, 2010 version of the ASCE 7 Standard provisions for wind loads; incorporate major advances achieved in recent years in the design of tall buildings for wind; present material on retrofitting and loss estimation; and improve the presentation of the material to increase its usefulness to structural engineers. Key features: New focus on tall buildings helps make the analysis and design guidance easier and less complex. Covers the new simplified design methods of ASCE 7-10, guiding designers to clearly understand the spirit and letter of the provisions and use the design methods with confidence and ease. Includes new coverage of retrofitting for wind load resistance and loss estimation from hurricane winds. Thoroughly revised and updated to conform with current practice and research.
Redeveloping Industrial Sites. A Guide for Architects, Planners, and Developers
The ultimate resource on strategies for redeveloping abandoned urban sites Architects, urban planners, urban designers, developers, city officials, and all those interested in revitalizing their post-industrial cities will find the tools they need here. Redeveloping Industrial Sites delivers solutions to complex issues concerning urban planning, design, and financing to reveal lessons on ways to successfully convert decaying land and buildings into vibrant parks, stimulating cultural destinations, and active commercial complexes. In addition, carefully chosen real-world examples illustrate topics such as sustainability, public policy, and developer know-how to form a complete picture of the elements involved in planning and executing urban redevelopment projects. Redeveloping Industrial Sites: Covers strategies used to turn abandoned industrial sites into vibrant new neighborhoods and special districts such as Toronto's Distillery District and Philadelphia's Piazza at Schmidts Emphasizes design and economic issues that urban planners and city officials need to plan successful projects as well as manage spontaneous neighborhood transformations such as loft conversions Includes case studies of a variety of redevelopments from across North America and Europe ranging from large projects such as New York's Hudson River Park and Amsterdam's harbor to the small, but important neighborhood regenerators such as Baltimore's American Brewery Building for Humanim Examines how cities from Minneapolis, Minnesota to North Adams, Massachusetts, to Swansea, Wales harnessed the forces of tourism and art to transform their mills and harbors Providing historical context as well as current perspective, Redeveloping Industrial Sites offers clear direction on repurposing derelict and polluted wastelands and warehouses into vital, living extensions of their communities.
Forest Entomology. A Global Perspective
Insects are the most abundant and diverse organisms that inhabit our planet and are found in all the world’s forest ecosystems. Many feed and/or breed on parts of trees. Some perform important functions, such as pollination or break-down of dead vegetation. Others weaken, deform or kill trees, and compete with humans for the many goods and services that trees and forests provide. Forest Entomology: A Global Perspective examines forest insects in a global context and reviews their dynamics, interactions with humans and methods for monitoring and management of species that damage forests. Also provided are 235 profiles of forest insects, worldwide. A series of tables provides summaries of the distribution and hosts of many more species. Included are those that damage forests, others that are simply curiosities and some that are beneficial. This book is designed as a reference for students, practicing foresters and forest health specialists, especially for those who work internationally or are concerned with species that have the potential to expand their ranges via international trade, travel or environmental changes.