John Wiley & Sons Limited
Все книги издательства John Wiley & Sons Limited
Mutagenic Impurities
Learn to implement effective control measures for mutagenic impurities in pharmaceutical development In Mutagenic Impurities: Strategies for Identification and Control , distinguished chemist Andrew Teasdale delivers a thorough examination of mutagenic impurities and their impact on the pharmaceutical industry. The book incorporates the adoption of the ICH M7 guideline and focuses on mutagenic impurities from both a toxicological and analytical perspective. The editor has created a primary reference for any professional or student studying or working with mutagenic impurities and offers readers a definitive narrative of applicable guidelines and practical, tested solutions. It demonstrates the development of effective control measures, including chapters on the purge tool for risk assessment. The book incorporates a discussion of N-Nitrosamines which was arguably the largest mutagenic impurity issue ever faced by the pharmaceutical industry, resulting in the recall of Zantac and similar drugs resulting from N-Nitrosamine contamination. Readers will also benefit from the inclusion of: A thorough introduction to the development of regulatory guidelines for mutagenic and genotoxic impurities, including a historical perspective on the development of the EMEA guidelines and the ICH M7 guideline An exploration of in silico assessment of mutagenicity, including use of structure activity relationship evaluation as a tool in the evaluation of the genotoxic potential of impurities A discussion of a toxicological perspective on mutagenic impurities, including the assessment of mutagenicity and examining the mutagenic and carcinogenic potential of common synthetic reagents Perfect for chemists, analysts, and regulatory professionals, Mutagenic Impurities: Strategies for Identification and Control will also earn a place in the libraries of toxicologists and clinical safety scientists seeking a one-stop reference on the subject of mutagenic impurity identification and control.
Application of Nanotechnology in Mining Processes
>Application of Nanotechnology in Mining Processes Nanotechnology has revolutionized processes in many industries but its application in the mining industry has not been widely discussed. This unique book provides an overview of the successful implementation of nanotechnology in some of the key environmental and beneficiation mining processes. This book explores extensively the potential of nanotechnology to revolutionize the mining industry which has been relying for a very long on processes with limited efficiencies. The nine specialized chapters focus on applying nanoflotation to improve mineral processing, effective extraction of metals from leachates or pregnant solutions using nanoscale supramolecular hosts, and development of nano-adsorbents or nano-based strategies for the remediation or valorization of AMD. The application of nanotechnology in mining has so far received little attention from the industry and researchers and this groundbreaking book features critical issues so far under-reported in the literature: Application of nanotechnology in mineral processing for the enhancement of froth flotation Development of smart nanomaterials and application for the treatment of acid mine drainage Recovery of values from pregnant solutions using nanoadsorbents Valorization of AMD through formation of multipurpose nanoproducts. Audience Industrial interest will be from mining plant operators, environmental managers, water treatment plants managers, and operators. Researchers in nanotechnology, environmental science, mining, and metallurgy engineering will find the book valuable, as will government entities such as regulatory bodies officers and environmentalists.
Landscaping For Dummies
Create an eye-catching outdoor oasis with this no-nonsense guide to landscaping As families spend more time at home, they're expanding their living space to their yards, decks, and patios. When you're ready to upgrade the look of your landscape, Landscaping For Dummies offers advice on installing fences and walkways, choosing hardy plants and trees, and enhancing natural habitats for the critters and creatures lurking in your neighborhood. You'll find out how to make your backyard a relaxing retreat space and discover the enjoyment and satisfaction that comes from working in your yard. Landscaping For Dummies includes: Lists of recommended plants and varieties, including the best ones for privacy plantings, low-maintenance groundcovers, and small gardens Advice on how to deal with special landscaping concerns, including fire-prone areas, bee and butterfly gardens, and drought-tolerant and native landscapes Instructions on installing permanent features like decks, patios, fences, and more Pointers on how to water more efficiently, including the latest tools and technologies that can save you time With a little bit of planning and some digging, trimming, or planting, you'll be set to enjoy your yard whenever the mood strikes. Let Landscaping For Dummies be your guide to making the most of your outdoor space.
