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Bioactive compounds play a central role in high-value product development in the chemical industry. Bioactive compounds have been identified from diverse sources and their therapeutic benefits, nutritional value and protective effects in human and animal healthcare have underpinned their application as pharmaceuticals and functional food ingredients. The orderly study of biologically active products and the exploration of potential biological activities of these secondary metabolites, including their clinical applications, standardization, quality control, mode of action and potential biomolecular interactions, has emerged as one of the most exciting developments in modern natural medicine. Biotechnology of Bioactive Compounds describes the current stage of knowledge on the production of bioactive compounds from microbial, algal and vegetable sources. In addition, the molecular approach for screening bioactive compounds is also discussed, as well as examples of applications of these compounds on human health. The first half of the book comprises information on diverse sources of bioactive compounds, ranging from microorganisms and algae to plants and dietary foods. The second half of the book reviews synthetic approaches, as well as selected bioactivities and biotechnological and biomedical potential. The bioactive compounds profiled include compounds such as C-phycocyanins, glycosides, phytosterols and natural steroids. An overview of the usage of bioactive compounds as antioxidants and anti-inflammatory agents, anti-allergic compounds and in stem cell research is also presented, along with an overview of the medicinal applications of plant-derived compounds. Biotechnology of Bioactive Compounds will be an informative text for undergraduate and graduate students of bio-medicinal chemistry who are keen to explore the potential of bioactive natural products. It also provides useful information for scientists working in various research fields where natural products have a primary role.
Starter Cultures in Food Production
Starter cultures have great significance in the food industry due to their vital role in the manufacture, flavour, and texture development of fermented foods. Once mainly used in the dairy industry, nowadays starter cultures are applied across a variety of food products, including meat, sourdough, vegetables, wine and fish. New data on the potential health benefits of these organisms has led to additional interest in starter bacteria. Starter Cultures in Food Production details the most recent insights into starter cultures. Opening with a brief description of the current selection protocols and industrial production of starter cultures, the book then focuses on the innovative research aspects of starter cultures in food production. Case studies for the selection of new starter cultures for different food products (sourdough and cereal based foods, table olives and vegetables, dairy and meat products, fish and wine) are presented before chapters devoted to the role of lactic acid bacteria in alkaline fermentations and ethnic fermented foods. This book will provide food producers, researchers and students with a tentative answer to the emerging issues of how to use starter cultures and how microorganisms could play a significant role in the complex process of food innovation.
Clostridial Diseases of Animals
Clostridial Diseases of Animals is the first book to focus on clostridial diseases in domestic and wild animals, offering a comprehensive reference on these common diseases. Provides a single resource for all aspects of clostridial diseases Presents current, comprehensive information with a focus on clinical relevance Covers each disease in depth, including etiology, epidemiology, clinics, gross pathology, histopathology, diagnostics, diagnostic criteria, prophylaxis, control, and treatment Written by the world-leading experts in the field of clostridial diseases in animals Offers photographs and summary tables to support the concepts discussed in the text and aid in recognition
Bio-Nanomaterials. Designing Materials Inspired by Nature
Written by authors from different fields to reflect the interdisciplinary nature of the topic, this book guides the reader through new nano-materials processing inspired by nature. Structured around general principles, each selection and explanation is motivated by particular biological case studies. This provides the background for elucidating the particular principle in a second section. In the third part, examples for applying the principle to materials processing are given, while in a fourth subsection each chapter is supplemented by a selection of relevant experimental and theoretical techniques.
Applications of Regression Models in Epidemiology
A one-stop guide for public health students and practitioners learning the applications of classical regression models in epidemiology This book is written for public health professionals and students interested in applying regression models in the field of epidemiology. The academic material is usually covered in public health courses including (i) Applied Regression Analysis, (ii) Advanced Epidemiology, and (iii) Statistical Computing. The book is composed of 13 chapters, including an introduction chapter that covers basic concepts of statistics and probability. Among the topics covered are linear regression model, polynomial regression model, weighted least squares, methods for selecting the best regression equation, and generalized linear models and their applications to different epidemiological study designs. An example is provided in each chapter that applies the theoretical aspects presented in that chapter. In addition, exercises are included and the final chapter is devoted to the solutions of these academic exercises with answers in all of the major statistical software packages, including STATA, SAS, SPSS, and R. It is assumed that readers of this book have a basic course in biostatistics, epidemiology, and introductory calculus. The book will be of interest to anyone looking to understand the statistical fundamentals to support quantitative research in public health. In addition, this book: • Is based on the authors’ course notes from 20 years teaching regression modeling in public health courses • Provides exercises at the end of each chapter • Contains a solutions chapter with answers in STATA, SAS, SPSS, and R • Provides real-world public health applications of the theoretical aspects contained in the chapters Applications of Regression Models in Epidemiology is a reference for graduate students in public health and public health practitioners. ERICK SUÁREZ is a Professor of the Department of Biostatistics and Epidemiology at the University of Puerto Rico School of Public Health. He received a Ph.D. degree in Medical Statistics from the London School of Hygiene and Tropical Medicine. He has 29 years of experience teaching biostatistics. CYNTHIA M. PÉREZ is a Professor of the Department of Biostatistics and Epidemiology at the University of Puerto Rico School of Public Health. She received an M.S. degree in Statistics and a Ph.D. degree in Epidemiology from Purdue University. She has 22 years of experience teaching epidemiology and biostatistics. ROBERTO RIVERA is an Associate Professor at the College of Business at the University of Puerto Rico at Mayaguez. He received a Ph.D. degree in Statistics from the University of California in Santa Barbara. He has more than five years of experience teaching statistics courses at the undergraduate and graduate levels. MELISSA N. MARTÍNEZ is an Account Supervisor at Havas Media International. She holds an MPH in Biostatistics from the University of Puerto Rico and an MSBA from the National University in San Diego, California. For the past seven years, she has been performing analyses for the biomedical research and media advertising fields.
Satellite and Terrestrial Hybrid Networks
This book offers the reader the keys for a successful understanding, integration and usage of satellite systems in addition to next generation terrestrial networks. The DVB-S2/RCS system is used to illustrate the integration challenges. The presentation uses a system approach, i.e. it tackles the terrestrial and satellite telecommunication systems’ complexity with a high level approach, focusing on the systems’ components and on their interactions. Several scenarios present the different paths that can be followed for the integration of satellite systems in terrestrial networks. Quality of Service management techniques in terrestrial and satellite systems and the solutions to help them to interoperate are provided. Inter-system mobility solutions and performance problems are then addressed. The solutions proposed in this book have been developed within the framework of European and French funded research projects and tested with simulated or real testbeds.
Abriss der Bierbrauerei
Das Lehrbuch zur Bierbrauerei von Ludwig Narzi? ist seit vielen Jahren das Standardwerk auf diesem Gebiet. Die neue, achte Auflage wurde komplett uberarbeitet und aktualisiert. Fur Studenten ist das Buch ein kurz gefasster Leitfaden, der jedoch alle wesentlichen Aspekte abdeckt. Der bereits im Betrieb tatige Praktiker erhalt eine Fulle von Anregungen und einen umfassenden Uberblick uber den heutigen Stand der Brauereitechnologie sowie der naturwissenschaftlichen Grundlagen der Bierbrauerei. Neu in dieser Auflage: * das Kapitel «Die Deutschen Biertypen» * das Kapitel «Malze aus anderen Getreidearten und deren Verarbeitung» * weiterfuhrende Literatur ab Kapitel 3 Das Autorenteam ist um drei hervorragende Fachleute auf dem Gebiet der Bierbrauerei erweitert worden. Werner Back, Martin Zarnkow und Martina Gastl (alle Technische Universitat Munchen, Weihenstephan) stehen fur die kontinuierliche Weiterentwicklung dieses Lehrbuches.
Model-Based System Architecture
Presents modeling approaches that can be performed in SysML and other modeling languages This book combines the emerging discipline of systems architecting with model-based approaches using SysML. The early chapters of the book provide the fundamentals of systems architecting; discussing what systems architecting entails and how it benefits systems engineering. Model-based systems engineering is then defined, and its capabilities to develop complex systems on time and in a feasible quality are discussed. The remainder of the book covers important topics such as: architecture descriptions; architecture patterns; perspectives, viewpoints, views and their relation to system architecture; the roles of a system architect, their team, and stakeholders; systems architecting processes; agile approaches to systems architecting; variant modeling techniques; architecture frameworks; and architecture assessment. The book's organization allows experts to read the chapters out of sequence. Novices can read the chapters sequentially to gain a systematic introduction to system architecting. Model-Based System Architecture: Provides comprehensive coverage of the Functional Architecture for Systems (FAS) method created by the authors and based on common MBSE practices Covers architecture frameworks, including the System of Systems, Zachman Frameworks, TOGAF®, and more Includes a consistent example system, the “Virtual Museum Tour” system, that allows the authors to demonstrate the systems architecting concepts covered in the book Model-Based System Architecture is a comprehensive reference for system architects and systems engineers in technology companies. This book will also serve as a reference to students and researchers interested in functional architectures. Tim Weilkiens is the CEO at the German consultancy oose Innovative Informatik and co-author of the SysML specification. He has introduced model-based systems engineering to a variety of industry sectors. He is author of several books about modeling and the MBSE methodology SYSMOD. Jesko G. Lamm is a Senior Systems Engineer at Bernafon, a Swiss manufacturer for hearing instruments. With Tim Weilkiens, Jesko G. Lamm founded the Functional Architectures working group of the German chapter of INCOSE. Stephan Roth is a coach, consultant, and trainer for systems and software engineering at the German consultancy oose Innovative Informatik. He is a state-certified technical assistant for computer science from Physikalisch-Technische Lehranstalt (PTL) Wedel and a certified systems engineer (GfSE)®– Level C. Markus Walker works at Schindler Elevator in the research and development division as elevator system architect. He is an INCOSE Certified Systems Engineering Professional (CSEP) and is engaged in the committee of the Swiss chapter of INCOSE.
Metrology and Standardization for Nanotechnology. Protocols and Industrial Innovations
For the promotion of global trading and the reduction of potential risks, the role of international standardization of nanotechnologies has become more and more important. This book gives an overview of the current status of nanotechnology including the importance of metrology and characterization at the nanoscale, international standardization of nanotechnology, and industrial innovation of nano-enabled products. First the field of nanometrology, nanomaterial standardization and nanomaterial innovation is introduced. Second, major concepts in analytical measurements are given in order to provide a basis for the reliable and reproducible characterization of nanomaterials. The role of standards organizations are presented and finally, an overview of risk management and the commercial impact of metrology and standardization for industrial innovations.
Pharmaceutical Nanotechnology. Innovation and Production, 2 Volumes
With its focus on concrete methods and recent advances in applying nanotechnology to develop new drug therapies and medical diagnostics, this book provides an overall picture of the field, from the fundamentals of nanopharmacy with the characterisation and manufacturing methods to the role of nanoparticles and substances. Actual examples of utilization include drug development issues, translation to the clinic, market prospects, and industrial commercialization aspects. The applications described are taken from cancer treatment as well as other major therapeutic areas, such as infectious diseases and dermatology. An in-depth discussion on safety, regulatory, and societal aspects rounds off the book. Written by a top team of editors and authors composed of the leading experts in Europe and the USA who have pioneered the field of nanopharmacy!