Прочая образовательная литература
Различные книги в жанре Прочая образовательная литератураGlobal Environmental Issues
Meeting the needs of upper level students, this book treats global environmental problems as complex issues with a network of human and biophysical causes. Each chapter interlinks human demands on the Earth's resources to natural biophysical change – not simply a 'cause and effect' treatment of global issues and environmental change Includes coverage of contemporary hot topics such as biodiversity, urbanisation and sustainable development Global case studies (two per chapter) contextualise theory for students «This book should have considerable appeal among undergraduate and postgraduate students in a broad range of disciplines. Frances Harris has assembled a team of well-qualified authors, who between them consider such important environmental issues as climate and sea level change, biodiversity, GM crops, energy supply, urbanization, pollution and sustainable development. The style is clear and non-technical, the coverage is global and the text is supported by numerous figures and illustrations. Boxed case studies provide useful exemplification of general issues. I have no doubt that this book will be very popular with my own students, in providing detailed analysis of a range of key environmental issues which are frequently reported in the media.» Tony Binns, University of Sussex, UK «This book usefully realises that environmental issues are a complex blend of contested science, broader socio-political contexts and the concerns, values, attitudes and livelihoods of individuals. Written by internationally recognised authors, it covers major global issues such as pollution, energy, climate change, sea level rise, food production, urbanisation and sustainability in an informative way, with abundant case studies and illustrations, which clearly exemplify just how complex the facets of the issues can be. It does not offer easy solutions but it is a good exercise in awareness for the reader.» Stephen Trudgill, Robinson College, University of Cambridge, UK
Single Cell Analysis
The first-ever comprehensive overview of the methods used in this key technology in modern biology provides the latest working knowledge needed by every scientist entering this growing field. It covers all the current technology and application areas, from microscopy and spectroscopy to proteomics and microfluidics.
Tumor-Associated Antigens
The first comprehensive and most recent overview of the topic, this ready reference and handbook reviews current knowledge of TAAs, their subclasses, and pinpoints their application areas in medicine. In addition, it emphasizes target identification procedures, the need for an accurate and thorough analysis of the function of TAAs, and the validation of those in clinical settings. The whole is rounded off with an overview of currently approved therapeutic antibodies. The result is a must-have for biologists and oncologists in science, clinics and industry.
Photosynthetic Protein Complexes
Perfectly timed, this handbook covers many important aspects of the topic that have only recently been understood – making this a truly comprehensive work. With its extensive use of color, it surveys the most important proteins involved in photosynthesis, discussing the structural information we have at our disposal. Most chapters are dedicated to one protein, while a few also summarize general associated concepts. The book also has an accompanying website that contains data files and animations to allow readers to visualize many of the complicated proteins presented. A must for anyone studying photosynthesis and structural biology, as well as those working in the plant and crop biotechnology industry.
Proteomics in Practice
Still the only concise practical guide to laboratory experiments in proteomics, this new edition now also covers DIGE technology and liquid-chromatography, while the troubleshooting section has been considerably extended. Adopting a practical approach, the authors present the relevant techniques and explain the route to successful experimental design and optimal method selection. They cover such electrophoretic techniques as isoelectric focusing, SDS page, 2-D page, and DIGE, as well as liquid-chromatography techniques, such as ion exchange, affinity chromatography and reversed-phase HPLC. Mass-spectrometric techniques include MALDI, ESI, and FT ICR. Generously illustrated, partly in color, the book also features updates of protocols as well as animations illustrating crucial methodological steps on a companion website.
Microbial Transport Systems
Transport of molecules across the cell membrane is a fundamental process of all living organisms. It is essential for understanding growth, development, nutrition as well as uptake and excretion of exogenous or synthesized molecules. Microbes respresent general and basic functional systems where many transport processes have been studied on a molecular basis. Knowledge of the microbial transport processes will provide new perspectives to treatments by inhibitors, drugs, antibiotics, vitamins, growth promotion compounds, activators and toxic compunds of various kinds.
Stem Cell Transplantation
This is the first handbook on the whole field of stem cell research covering (1) molecular and cellular fundamentals, (2) clinical applications and (3) GMP processing. It provides a timely overview of the potential and plasticity of adult stem cells. With its focus on standardization and quality control of cell lines suited for processing and clinical trials, the book features novel therapeutic approaches that offer great promise for new ways of treating neural, hematological and cardiovascular diseases. The editors are leading international experts in adult stem cell research, and their successful networking in the US and Europe has resulted in a distinguished team of authors from around the world.
Antigen Presenting Cells
This novel, multidisciplinary handbook highlights recent evidence that antigen presenting cells (APCs) are not only key players in the initiation or prevention of an antigen-specific T lymphocyte-mediated adaptive immune response, but also critical regulators and integrators in the interplay between our innate and adaptive immune system. Structured in a clear way to allow access to a very broad readership, the book is written from the viewpoint of a biochemist, immunologist, and scientist with experience in drug development. It covers all cell types involved in antigen presentation, providing the latest immunological facts with a focus on drug development. Backed by a glossary explaining all important technical terms, this short but comprehensive reference covers basic introductory aspects right up to details for advanced specialists.
Novel Vaccination Strategies
The protection mode of most available vaccines is based on antibody responses. Since efficient immune responses to many pathogens rely on activating all arms of the immune system, traditional vaccine development does not provide efficient protection against many diseases. Novel vaccination strategies need to allow presentation of antigens that activate the full array of the immune response in the right composition and should prevent pathogen entry by mobilizing the mucosal immune response. New technological advances optimize the immunogenicity of 'live' and sub-unit vaccines. This book offers an interdisciplinary overview on research and future strategies for rational vaccine design based on recent developments in molecular biology and immunology. It covers new aspects of the immunological interplay between prokaryotic and eukaryotic systems as well as achievements in the development of novel vaccine candidates. Chapters on edible vaccines, on vaccines against bioterror agents and on economical and safety aspects of novel vaccine development round off this title.
Modular Protein Domains
Since the full functionality of any given protein can only be understood in terms of its interaction with other, often regulatory proteins, this unique reference source covers all relevant protein domains, including SH2, SH3, PDZ, WW, PTB, EH, PH and PX. Its user-oriented concept combines broad coverage with easy retrieval of essential information, and includes a special section on Web-based tools and databases covering protein modules and functional peptide motifs. Essential for the study of protein-protein interactions in vivo or in silico, and a prerequisite for successful functional proteomics studies. With a prologue by Sir Tom Blundell.