Медицина
Различные книги в жанре МедицинаCommunicable Disease Control and Health Protection Handbook
Health protection professionals need rapid access to authoritative and easy-to-use information to ensure their actions are based on international best practice. This is precisely what the Communicable Disease Control and Health Protection Handbook does. This concise and practical handbook is an essential guide for all those who have responsibility for the identification and control of infectious disease. In the past five years, there have been many major changes in health protection practice, and significant scientific progress in the field, all of which are reflected in this new edition of the popular Communicable Disease Control and Health Protection Handbook. All chapters have been updated in line with recent changes in epidemiology, new guidelines for control and administrative changes. Basic principles of communicable disease control and health protection, major syndromes, control of individual infections, main services and activities, organizational arrangements for all EU countries and sources of further information are covered. A new chapter on pandemic planning has been included, and the influenza chapter has been expanded to cover seasonal, avian and pandemic flu. Communicable Disease Control and Health Protection Handbook is an indispensible companion for all those who are engaged in health protection, including public health physicians, epidemiologists, infection control nurses, microbiologists and trainees in the field.
Nutritional and Metabolic Bases of Cardiovascular Disease
Extraordinary advances in the understanding of the links between nutrition, metabolism, and cardiovascular disease have prompted a systematic reappraisal of knowledge in the field. As a result, it is now imperative that clinicians who care for patients with CVD or its key risk factors have a solid understanding of the often complex interrelationships between cardiovascular health and chronic diseases such as diabetes and obesity. Written by a team of international thought leaders in cardiology, endocrinology, diabetology and nutritional science, this important new book: Examines and updates the role of obesity, hyperlipidemia, diabetes, hypertension, thrombosis, and aging in atherogenesis Describes in detail the scientific and clinical evidence of the etiopathogenesis of ischemic heart disease as well as of peripheral and cerebrovascular disease Focuses on the 6 topics that will be of greatest interest to readers: 1) general nutrition, 2) metabolic syndrome and diabetes, 3) hyperlipidemia and atherosclerosis, 4) hypertension and cerebrovascular disease, 5) hemostasis and thrombosis, 6) aging Throughout the book, in clear and accessible text, contributors illuminate the close relationship between dietary habits, the metabolic processes of nutrients, and their impact on the cardiovascular system, always with an eye on how the physician can use this information to implement better cardiovascular prevention and improve patient care. Nutritional and Metabolic Bases of Cardiovascular Disease is ideal for those who need to update their knowledge of the links between nutrition, metabolism and CVD, from trainees, clinicians and clinical investigators in cardiovascular medicine to endocrinologists, diabetologists, and nutritionists.
Microneedle-mediated Transdermal and Intradermal Drug Delivery
Microneedles can be used for delivery of a wide range of drug substances for practically any medical condition and present a real opportunity for vaccines and medicines that are unsuitable for oral administration or conventional patch delivery. Microneedle-mediated Transdermal and Intradermal Drug Delivery covers the major aspects relating to the use of microneedle arrays in enhancing drug delivery applications. It provides an overview of the various methods employed to design and produce microneedles, from the different materials involved to the importance of application methods. It carefully and critically reviews ongoing transdermal and intradermal delivery research using microneedles and includes the outcomes of in vivo animal and human studies. Importantly, it also discusses the safety and patient acceptability studies carried out to date. Finally, the book reviews the recent patents in microneedle research and describes the ongoing developments within industry that will determine the future of microneedle-mediated transdermal and intradermal drug delivery. By an expert author team with practical experience in the design and development of drug delivery systems this is the only text that provides a comprehensive review of microneedle research in transdermal and intradermal drug delivery.
Statistical Modelling of Molecular Descriptors in QSAR/QSPR
This handbook and ready reference presents a combination of statistical, information-theoretic, and data analysis methods to meet the challenge of designing empirical models involving molecular descriptors within bioinformatics. The topics range from investigating information processing in chemical and biological networks to studying statistical and information-theoretic techniques for analyzing chemical structures to employing data analysis and machine learning techniques for QSAR/QSPR. The high-profile international author and editor team ensures excellent coverage of the topic, making this a must-have for everyone working in chemoinformatics and structure-oriented drug design.
Visual Diagnosis in Emergency and Critical Care Medicine
Improve your skills in visual diagnosis Speed and accuracy of diagnosis is the key to saving lives in emergency and critical care medicine. Careful visual inspection of the patient, the data (radiography, electrocardiogram), and related clues can often help providers choose the right diagnosis and ultimately the best treatment – but this knowledge comes with experience. This book provides 110 randomly presented visual diagnosis cases for self-testing, imitating real-life situations found in the emergency department setting. Written by distinguished emergency and critical care physicians, and thoroughly revised and updated throughout, this second edition includes 25% new cases and is an ideal aid for trainees preparing for Board examinations as well as an invaluable ‘refresher’ for qualified emergency and critical care providers. This title is also available as a mobile App from MedHand Mobile Libraries. Buy it now from Google Play or the MedHand Store.
100 Top Consultations in Small Animal General Practice
Focusing on 'day one competencies', this book offers essential guidance to the most common problems encountered in small animal general practice. Addressing 100 core scenarios, it is ideal for the undergraduate or newly qualified vet, and for those seeking an up-to-date refresher. Organized by presenting sign (diarrhoea, itching) or disease (diabetes mellitus, pancreatitis), and with colour illustration throughout, each chapter explains: how to make a diagnosis which interventions are most appropriate in general practice what the vet should say to the client before and after examination The authors also offer invaluable advice on other key topics such as annual health checks, neutering and euthanasia, and they tackle the tough questions: What if it doesn't get better? What is the low cost option? When should I refer? Never before has so much practical information been brought together in a single volume. Like having an experienced or specialist clinician standing by your side in the consulting room, 100 Top Consultations will become a trusted companion for students and practitioners alike.
Exercise Therapy in the Management of Musculoskeletal Disorders
Exercise Therapy in the Management of Musculoskeletal Disorders covers the fundamentals of using exercise as a treatment modality across a broad range of pathologies including osteoarthritis, inflammatory arthropathies and osteoporosis. As well as offering a comprehensive overview of the role of exercise therapy, the book evaluates the evidence and puts it to work with practical ideas for the management of musculoskeletal disorders in different areas of the body, for differing pathologies and for a range of patients. Part 1 introduces the reader tothe role of exercise in managing musculoskeletal disorders and covers measurement and assessment. Part 2 looks at the regional application of exercise therapy with chapters on areas of the body such as the cervical spine, the shoulder complex and the knee. Part 3 examines specific populations: the developing child, the cardiac and respiratory patient, obesity and osteoporosis. Exercise Therapy in the Management of Musculoskeletal Disorders is an invaluable resource for student physiotherapists as well as clinicians designing rehabilitation programmes for their patients. KEY FEATURES Concise and comprehensive Team of expert contributors Offers practical guidance Evaluates the evidence
Critical Pathways to Success in CNS Drug Development
Covering the latest advances in CNS drug development, this book will guide all those involved in pre-clinical to early clinical trials. The authors describe how recent innovations can accelerate the development of novel CNS compounds, improve early detection of efficacy and toxicity signals, and increase the safety of later-stage clinical trials. The current crisis in the drug development industry is critically reviewed, as well as the steps needed to correct the problems, including new government-backed regulations and industry-based innovations designed to accelerate CNS drug development in the future. Animal-based models of major CNS disorders are described in detail, and the ability of the latest in vitro and computer-based models to simulate CNS disease states and predict drug efficacy and side-effects are examined. Particular attention is given to the growing use of biomarkers and how they can be used effectively in early human trials as signals of potential drug efficacy, as well as the increasingly important role of imaging studies to guide dose selection. Cognitive assessments that can be useful indicators of effect in patient populations are also discussed. Written by a team of clinical scientists involved in CNS drug trials for over 20 years, and based on a wealth of drug development and clinical trial experience, Critical Pathways to Success in CNS Drug Developmentis full of practical advice for successfully designing and executing CNS drug trials, avoiding potential pitfalls, and complying with government regulations
Anatomy of the Heart by Multislice Computed Tomography
New MSCT machines produce a volume data set with the highest isotropic spatial resolution ever seen, offering superb 3D images of the entire heart and vessels. The texts currently available on cardiac CT imaging mainly focus on visualizing pathological aspects of coronary arteries. Anatomy of the Heart by Multislice Computed Tomography is the first text to bridge the gap between classical anatomy textbooks and CT textbooks, presenting a side-by-side comparison of ‘electronic’ dissection made by CT scanning and traditionally hand-made anatomical dissection. Focusing on the fundamentals as well as the details of cardiac anatomy in a clinical setting using MSCT, this is an invaluable reference for cardiac imaging trainees, cardiologists, radiologists, interventionists and electrophysiologists, providing a better understanding of the cardiac structures, coronary arteries and veins anatomy and their 3-dimensional spatial relationships.
Vaccines and Autoimmunity
In light of the discovery of Autoimmune Syndrome Induced by Adjuvants, or ASIA, Vaccines and Autoimmunity explores the role of adjuvants – specifically aluminum in different vaccines – and how they can induce diverse autoimmune clinical manifestations in genetically prone individuals. Vaccines and Autoimmunity is divided into three sections; the first contextualizes the role of adjuvants in the framework of autoimmunity, covering the mechanism of action of adjuvants, experimental models of adjuvant induced autoimmune diseases, infections as adjuvants, the Gulf War Syndrome, sick-building syndrome (SBS), safe vaccines, toll-like receptors, TLRS in vaccines, pesticides as adjuvants, oil as adjuvant, mercury, aluminum and autoimmunity. The following section reviews literature on vaccines that have induced autoimmune conditions such as MMR and HBV, among others. The final section covers diseases in which vaccines were known to be the solicitor – for instance, systemic lupus erythematosus – and whether it can be induced by vaccines for MMR, HBV, HCV, and others. Edited by leaders in the field, Vaccines and Autoimmunity is an invaluable resource for advanced students and researchers working in pathogenic and epidemiological studies.