Essential Guide to Blood Groups is the only pocket sized guide to provide essential information on blood group systems. The main aim of the blood transfusion laboratory is to promote safe blood transfusion. The avoidance of errors, from sample receipt and laboratory testing through to the release of blood for transfusion, is of paramount importance. Knowledge of immunohaematology theory and its application to blood transfusion together with the principles of good laboratory practice are essential. This handbook helps to address these important issues and also covers: • the serology, inheritance, biochemistry, and molecular genetics of the most important blood group systems • their clinical importance • techniques used in blood grouping, troubleshooting, and quality assurance This unique and practical guide: • is written by leaders in the field, including the author of the best seller Human Blood Groups • provides the basic knowledge of blood groups needed by all those working in the important fields of transfusion medicine and science. • helps in resolving commonly encountered problems Essential Guide to Blood Groups will be valuable for undergraduate medical laboratory scientists and for postgraduate scientists and medical practitioners training to specialise in transfusion and transplantation. As a pocket edition, it will also be a useful addition to other reference works on blood groups for quick access to information for medical practitioners and in red cell immunohaematology laboratories.
Everything you need to know about Pathophysiology… at a Glance! From the publishers of the market-leading at a Glance series, and from the authors of the successful Fundamentals of Applied Pathophysiology textbook comes the ideal revision guide for all the key diseases and conditions that nursing and healthcare students need to be aware of. Combining superb illustrations with accessible and informative text, this book is perfect for all nursing and healthcare students, and anyone who is looking for an overview of pathophysiology. Pathophysiology for Nurses at a Glance covers all the key diseases and disease processes affecting each body system, and key concepts encountered from the start of the pre-registration nursing or healthcare course. Key features: Superbly illustrated, with full colour illustrations throughout Written specifically for nursing and healthcare students with all the information they need Self-assessment questions provided for each chapter Pathophysiology for Nurses at a Glance is ideal for nursing and healthcare students as well as qualified practitioners, providing a comprehensive yet accessible overview of human pathophysiology.
Fundamentals of Applied Pathophysiology is designed specifically for nursing and healthcare students, providing a straightforward, jargon-free, accessible introduction to pathophysiology. Highly visual and written specifically for students, the second edition of this best-selling textbook provides clear explanations of the anatomy of the human body, and the effects of disease or illness on normal physiology. To make study easier, the book includes learning outcomes, a range of activities to test learning, key words, end-of-chapter glossaries, and clinical case scenarios, and is supported by an online resource centre with further activities and exercises. Key Features: Superb full colour illustrations, bringing this subject to life Full of extra features to help improve the learning process, including key words, test-your-knowledge, exercises, further reading and learning outcomes New case studies throughout to help you understand how to apply the knowledge in clinical practice Supported by an online resource centre at www.wiley.com/go/fundamentalsofappliedpathophysiology with fantastic extras for both lecturers and students, including an image bank, interactive multiple choice questions, true/false exercises, word-searches, glossary flash-cards, label-the diagram activities, and more!
Fundamentals of Palliative Care for Student Nurses is a thorough yet accessible introduction and overview of a key area of the nursing programme. This textbook clearly explains the palliation of symptoms and the social context of death and dying. Engaging with the latest guidelines and curriculum, it highlights the practical and communicative skills required for induction programmes and continuing professional development. KEY FEATURES: A full-colour, student-friendly, introduction to the essentials of palliative, or end of life care A topical and timely subject area, explored clearly and concisely Full of interactive pedagogy and features, including quizzes, multiple choice questions, vignettes/case studies and activities Features a companion website with links to further reading, additional activities and resources, and self-testing interactive multiple choice questions Fundamentals of Palliative Care for Student Nurses focuses on this area with expert knowledge and compassion, preparing students in order to help them provide the best possible care for their patients and their families.
“This informative book has been put together with the support and input of many clinical renal experts, who have been willing to share their knowledge and years of experience and I’m sure it will be an excellent resource for those caring for kidney patients for the first time – as well as for those with some years of experience!” – From the Foreword by Rosemary Macri, Chief Executive of the British Kidney Patient Association Kidney Disease Management has been written to help optimise the care of people with chronic kidney disease (CKD) across the healthcare spectrum. It is aimed at a range of professionals, including nurses, junior doctors, general practitioners, pharmacists and dietitians. Specialists in training may also find it useful. It highlights the practical considerations necessary to care for people with kidney problems in situations where a specialist practitioner is not always required or immediately available. This book explores: policy context and CKD overview of CKD and management managing CKD in primary care treatment modalities in CKD psychosocial aspects of living with CKD Acute kidney injury in hospitalised patients surgery and kidney injury medication management in CKD nutrition and CKD support and palliative care for people with CKD Key features: Based on best practice and written in an accessible format aimed at busy practitioners Emphasises the centrality of the patient and family and the need to share information and expertise across traditional boundaries Written by professionals renowned in their field, both generalists and specialists, who have extensive experience of the practicalities of managing complex patients
With a focus on functional relationships between drugs and their targets, this book covers basic and general pharmacology, from a cellular and molecular perspective, with particular attention to the mechanisms of drug action – the fundamental basis for proper clinical use- without neglecting clinical application, toxicology and pharmacokinetics. • Covers cell and molecular pharmacology, bringing together current research on regulation of drug targets, at a level appropriate for advanced undergrad and graduate students • Discusses the relevance of pharmacokinetics and drug development for the clinical application of drugs • Presents material from the perspective of drug targets and interaction, the theoretical basis of drug action analysis, and drug properties • Focuses on structure-function relationships of drug targets – informing about their biochemical and physiologic functions and experimental and clinical pathways for drug discovery and development • Has a companion website that offers a host of resources: short additional chapters about methodology, topics at the forefront of research, all figures and tables from the book, and Power Point slides
As improvements in living conditions and advances in modern medicine lead to increased life expectancy and the number of older adults world-wide continues to grow, so the number of older individuals with cardiac and cerebrovascular disease is rising. Over eighty per cent of all cardiovascular disease-related deaths now occur in patients aged sixty five or older. The high prevalence of co-morbidities, frailty and cognitive decline amongst older patients requires that a holistic approach to the management of cardiovascular disease is required. Written and edited by leading experts in the field, ‘Cardiovascular diseases and health in the older patient’ provides scholarly evidence and data which explain why treating an older patient with cardiovascular disease is often different from treating a young or middle-aged patient with the same disease. The chapters have been updated and expanded from the cardiovascular section of the renowned ‘Pathy’s Principles and Practice of Geriatric Medicine’, edited by Alan J. Sinclair, John E. Morley and Bruno Vellas. The revised chapters contain updated evidence and references to recent clinical practice guidelines in Europe and North America, this book provides complete, authoritative information on this major cause of death, poor health and disability in old age. Covering the epidemiology, pathophysiology and management of cardiovascular disease in the older patient, the book is an excellent reference at all clinical and pre-clinical levels and will appeal particularly to geriatricians, cardiologists, and GPs, as well as cardiac specialist nurses and practice nurses. With a Foreword by Stuart M. Cobbe.
Handbook for Clinical Trials of Imaging and Image-Guided Interventions is the first single-source, multi-disciplinary reference, based on the didactic sessions presented at the annual ‘Clinical Trials Methodology Workshop’ for radiologists, radiation oncologists and imaging scientists (sponsored by the Radiological Society of North America (RSNA)). It focuses on educating radiologists, radiation oncologists and those involved in imaging research with how to design and conduct clinical trials to evaluate imaging technology and imaging biomarkers. The internationally renowned contributors take a broad approach, starting with principles of technology assessment, and then move into specific topics covering the clinical trials of therapy and clinical research in imaging guided interventions including radiotherapy. They discuss the use of imaging as a predictor of therapeutic response, screening trial design, and the practicalities of how to run an efficient clinical trial and good working practices. Later chapters provide a comprehensive array of quantitative methods including: an introduction to statistical considerations in study design, biostatistical analysis methods and their role in clinical imaging research, methods for quantitative imaging biomarker studies, and an introduction to cost effectiveness analysis. Handbook for Clinical Trials of Imaging and Image-Guided Interventions will educate and prepare radiologists at all levels and in all capacities in planning and conducting clinical imaging trials.
With an emphasis on the fundamental and practical aspects of ADME for therapeutic proteins, this book helps readers strategize, plan and implement translational research for biologic drugs. • Details cutting-edge ADME (absorption, distribution, metabolism and excretion) and PKPD (pharmacokinetic / pharmacodynamics) modeling for biologic drugs • Combines theoretical with practical aspects of ADME in biologic drug discovery and development and compares innovator biologics with biosimilar biologics and small molecules with biologics, giving a lessons-learned perspective • Includes case studies about leveraging ADME to improve biologics drug development for monoclonal antibodies, fusion proteins, pegylated proteins, ADCs, bispecifics, and vaccines • Presents regulatory expectations and industry perspectives for developing biologic drugs in USA, EU, and Japan • Provides mechanistic insight into biodistribution and target-driven pharmacokinetics in important sites of action such as tumors and the brain
Color Atlas of Equine Pathology offers a practical guide to identifying equine diseases, presenting a single resource with more than 1000 images showing predominantly gross pathology. Organized by body systems, the book allows for picture matching during or after an equine necropsy. In this user-friendly atlas, each chapter takes a common format, presenting the disease process as well as congenital, degenerative, inflammatory, and neoplastic sequences, with text boxes offering quick reference to key information. The book begins with an introductory chapter summarizing the principles of the equine field necropsy, and subsequent organ-based chapters depict gross features of disease, focusing on macroscopic digital images supplemented by histology and immunohistochemistry when necessary. Some clinical information for correlation with pathology is included. Color Atlas of Equine Pathology is an essential resource for diagnostic veterinary pathologists and pathology residents, as well as for equine practitioners performing necropsies in the field.