Медицина
Различные книги в жанре МедицинаMethodological Developments in Data Linkage
A comprehensive compilation of new developments in data linkage methodology The increasing availability of large administrative databases has led to a dramatic rise in the use of data linkage, yet the standard texts on linkage are still those which describe the seminal work from the 1950-60s, with some updates. Linkage and analysis of data across sources remains problematic due to lack of discriminatory and accurate identifiers, missing data and regulatory issues. Recent developments in data linkage methodology have concentrated on bias and analysis of linked data, novel approaches to organising relationships between databases and privacy-preserving linkage. Methodological Developments in Data Linkage brings together a collection of contributions from members of the international data linkage community, covering cutting edge methodology in this field. It presents opportunities and challenges provided by linkage of large and often complex datasets, including analysis problems, legal and security aspects, models for data access and the development of novel research areas. New methods for handling uncertainty in analysis of linked data, solutions for anonymised linkage and alternative models for data collection are also discussed. Key Features: Presents cutting edge methods for a topic of increasing importance to a wide range of research areas, with applications to data linkage systems internationally Covers the essential issues associated with data linkage today Includes examples based on real data linkage systems, highlighting the opportunities, successes and challenges that the increasing availability of linkage data provides Novel approach incorporates technical aspects of both linkage, management and analysis of linked data This book will be of core interest to academics, government employees, data holders, data managers, analysts and statisticians who use administrative data. It will also appeal to researchers in a variety of areas, including epidemiology, biostatistics, social statistics, informatics, policy and public health.
Hand Hygiene. A Handbook for Medical Professionals
The first comprehensive, authoritative review of one of the most fundamental and important issues in infection control and patient safety, hand hygiene. Developed and presented by the world's leading scholar-clinicians, Hand Hygiene is an essential resource for all medical professionals. Developed and presented by the world leaders in this fundamental topic Fully integrates World Health Organization (WHO) guidelines and policies Offers a global perspective in tackling hand hygiene issues in developed and developing countries Coverage of basic and highly complex clinical applications of hand hygiene practices Includes novel and unusual aspects and issues in hand hygiene such as religious and cultural aspects and patient participation Offers guidance at the individual, institutional, and organizational levels for national and worldwide hygiene promotion campaigns
Psychiatry. Breaking the ICE Introductions, Common Tasks, Emergencies for Trainees
Psychiatry: Breaking the ICE contains everything psychiatry trainees need in order feel confident and competent in general adult inpatient and community placements. A practical and reassuring guide to life as a psychiatrist, structured around the tasks expected both in day-to-day practice and in out-of-hours work Key themes running throughout the book include ethical and legal issues, risk assessment and management, patient experience and safe prescribing The authors are closely involved in the training, mentoring and supervision of core trainees, and know the real-world challenges faced by junior psychiatrists
Hämatologie. Theorie und Praxis für medizinische Assistenzberufe
Seit dem Erscheinen der ersten Auflage 1994 ist das Lehrbuch „Hämatologie” nicht mehr aus dem Ausbildungsangebot für Medizinisch-Technische Assistenten wegzudenken. Die dritte Auflage integriert nicht nur den neuesten Stand der MTA-Ausbildung, sondern präsentiert sich mit mehr didaktischen Merkmalen und einem übersichtlicheren Layout. Darüber hinaus wurden die folgenden Themen erweitert bzw. eingeführt: • Hämatologische Cytogenetik • Hämatologische Molekulargenetik • Antikörper-Diff erenzierung • Nachweis von Kälte-Agglutininen • Säure-Elution • Interne und externe Qualitätskontrolle in der Blutgruppenserologie.
Ethnic Dermatology. Principles and Practice
Ethnic Dermatology Principles and Practice Edited by Ophelia E. Dadzie, MB BS, MRCP, Centre for Clinical Science and Technology, University College London, Division of Medicine, Whittington Hospital Campus, London, UK Antoine Petit, MD, Department of Dermatology, Hôpital Saint-Louis, Paris, France Andrew F. Alexis, MD, FAAD, Director Skin of Color Center, Department of Dermatology, St Luke’s-Roosevelt Hospital Center, New York, NY, USA Richly pigmented skin is the most common skin type internationally Historically, dermatology has focused on white skin. But rich pigmentation can lead to differences in presentation, disease course and outcome, and reaction to treatment. Some dermatologic conditions are seen predominantly or only in richly pigmented skin. Ethnic Dermatology: Principles and Practice provides a practical approach to the dermatology of non-white skin. Written from a global perspective to include Asian, African-Caribbean and North African skin types, it covers all the bases of dermatology including: Grading scales in dermatologic disease Pediatric dermatology Dermatology and systemic disease Drug eruptions Hair and scalp disorders Cosmetic dermatology With a central focus on practical action from an international cast of authors, Ethnic Dermatology: Principles and Practice gives you the clinical tools you need when skin colour matters.
ECG from Basics to Essentials. Step by Step
This brand new guide assists students, interns and residents in developing a functional understanding of the set-up, workings and interpretation of ECGs Step-by-step graphics and short, bite-sized explanations Covers all major cardiac abnormalities including hypertrophy, arrhythmias, conduction blocks, and pre-excitation syndromes Begins with a section on physiology of the heart and the basic set up of ECG recording Features top tips on what to look for, complete with illustrated examples Supported by a companion website featuring additional practice tracings
Molecular Data Analysis Using R
This book addresses the difficulties experienced by wet lab researchers with the statistical analysis of molecular biology related data. The authors explain how to use R and Bioconductor for the analysis of experimental data in the field of molecular biology. The content is based upon two university courses for bioinformatics and experimental biology students (Biological Data Analysis with R and High-throughput Data Analysis with R). The material is divided into chapters based upon the experimental methods used in the laboratories. Key features include: • Broad appeal–the authors target their material to researchers in several levels, ensuring that the basics are always covered. • First book to explain how to use R and Bioconductor for the analysis of several types of experimental data in the field of molecular biology. • Focuses on R and Bioconductor, which are widely used for data analysis. One great benefit of R and Bioconductor is that there is a vast user community and very active discussion in place, in addition to the practice of sharing codes. Further, R is the platform for implementing new analysis approaches, therefore novel methods are available early for R users.
Biological Mechanisms of Tooth Movement
Biological Mechanisms of Tooth Movement, Second Edition is an authoritative reference to the scientific foundations underpinning clinical orthodontics. Led by an expert editor team and with contributions from an international group of contributors, the book covers key topics including bone biology, the effects of mechanical loading on tissues and cells, genetics, inflammation, tissue remodeling and the effects of diet, drugs, and systemic diseases. Highly-illustrated throughout, this second edition has been fully revised, updated and expanded to new developments in genomics, rapid orthodontics and current controversies in tooth movement research. Trainees, qualified specialists and researchers in orthodontics can rely on this comprehensive text to inform them about the clinical and scientific implications of the biological mechanisms involved in the movement of teeth.
Targeted Biomarker Quantitation by LC-MS
The first book to offer a blueprint for overcoming the challenges to successfully quantifying biomarkers in living organisms The demand among scientists and clinicians for targeted quantitation experiments has experienced explosive growth in recent years. While there are a few books dedicated to bioanalysis and biomarkers in general, until now there were none devoted exclusively to addressing critical issues surrounding this area of intense research. Target Biomarker Quantitation by LC-MS provides a detailed blueprint for quantifying biomarkers in biological systems. It uses numerous real-world cases to exemplify key concepts, all of which were carefully selected and presented so as to allow the concepts they embody to be easily expanded to future applications, including new biomarker development. Target Biomarker Quantitation by LC-MS primarily focuses on the assay establishment for biomarker quantitation—a critical issue rarely treated in depth. It offers comprehensive coverage of three core areas of biomarker assay establishment: the relationship between the measured biomarkers and their intended usage; contemporary regulatory requirements for biomarker assays (a thorough understanding of which is essential to producing a successful and defendable submission); and the technical challenges of analyzing biomarkers produced inside a living organism or cell. Covers the theory of and applications for state-of-the-art mass spectrometry and chromatography and their applications in biomarker analysis Features real-life examples illustrating the challenges involved in target biomarker quantitation and the innovative approaches which have been used to overcome those challenges Addresses potential obstacles to obtain effective biomarker level and data interpretation, such as specificity establishment and sample collection Outlines a tiered approach and fit-for-purpose assay protocol for target biomarker quantitation Highlights the current state of the biomarker regulatory environment and protocol standards Target Biomarker Quantitation by LC-MS is a valuable resource for bioanalytical scientists, drug metabolism and pharmacokinetics scientists, clinical scientists, analytical chemists, and others for whom biomarker quantitation is an important tool of the trade. It also functions as an excellent text for graduate courses in pharmaceutical, biochemistry and chemistry.
Successful Drug Discovery, Volume 2
Retaining the successful approach found in the previous volume in this series, the inventors and primary developers of drugs that successfully made it to market tell the story of the drug's discovery and development and relate the often twisted route from the first candidate molecule to the final marketed drug. 11 selected case studies describe recently introduced drugs that have not been previously covered in textbooks or general references. These range across six different therapeutic fields and provide a representative cross-section of the current drug development efforts. Backed by copious data and chemical information, the insight and experience of the contributors makes this one of the most useful training manuals that a junior medicinal chemist can hope to find and has won the support and endorsement of IUPAC.