Прочая образовательная литература
Различные книги в жанре Прочая образовательная литератураFormulation and Process Development Strategies for Manufacturing Biopharmaceuticals
A real-world guide to the production and manufacturing of biopharmaceuticals While much has been written about the science of biopharmaceuticals, there is a need for practical, up-to-date information on key issues at all stages of developing and manufacturing commercially viable biopharmaceutical drug products. This book helps fill the gap in the field, examining all areas of biopharmaceuticals manufacturing, from development and formulation to production and packaging. Written by a group of experts from industry and academia, the book focuses on real-world methods for maintaining product integrity throughout the commercialization process, clearly explaining the fundamentals and essential pathways for all development stages. Coverage includes: Research and early development phase–appropriate approaches for ensuring product stability Development of commercially viable formulations for liquid and lyophilized dosage forms Optimal storage, packaging, and shipping methods Case studies relating to therapeutic monoclonal antibodies, recombinant proteins, and plasma fractions Useful analysis of successful and failed products Formulation and Process Development Strategies for Manufacturing Biopharma-ceuticals is an essential resource for scientists and engineers in the pharmaceutical and biotech industries, for government and regulatory agencies, and for anyone with an interest in the latest developments in the field.
Formulating, Packaging, and Marketing of Natural Cosmetic Products
Balanced coverage of natural cosmetics, and what it really means to be «green» The use of natural ingredients and functional botanical compounds in cosmetic products is on the rise. According to industry estimates, sales of natural personal care products have exceeded $7 billion in recent years. Nonetheless, many misconceptions about natural products—for instance, what «green» and «organic» really mean—continue to exist within the industry. Formulating, Packaging, and Marketing of Natural Cosmetic Products addresses this confusion head-on, exploring and detailing the sources, processing, safety, efficacy, stability, and formulation aspects of natural compounds in cosmetic and personal care products. Designed to provide industry professionals and natural product development experts with the essential perspective and market information needed to develop truly «green» cosmetics, the book covers timely issues like biodegradable packaging and the potential microbial risks they present, the use of Nuclear Magnetic Resonance (NMR) to identify biomarkers, and chromatographic methods of analyzing natural products. A must-read for industry insiders, Formulating, Packaging, and Marketing of Natural Cosmetic Products provides the reader with basic tools and concepts to develop naturally derived formulas.
Clinical Physiology and Pharmacology. The Essentials
This book is an accessible collection of case study scenarios ideal for physiology and pharmacology revision for pharmacy, medical, biomedical science, clinical science and healthcare students. Clearly structured and organized by major organ system, the book emphasises ways in which key signs and symptoms of disease inform diagnosis and the choice of treatment, together with the relevant pharmacological mechanisms. Each chapter has a clinical focus and includes clear learning outcomes, key points and model answers with detailed explanations designed to enhance students’ understanding of the physiology and pharmacology underpinning each case study scenario. 50 topics are covered and the cases presented include an extensive range of psychological, neurological, endocrine, cardiovascular, respiratory, renal, gastrointestinal and reproductive disorders, their symptoms, complications and usual treatment along with the actions and uses of some widely- used drugs. An essential revision text designed to help students apply their theoretical knowledge to real-life cases Realistic case studies focusing on commonly occurring conditions and diseases Model answers throughout Learning outcomes provided at the beginning of each chapter Key learning points presented in the cases follow each model answer Helps students to understand the relevance and clinical implications of the topics studied in physiology and pharmacology courses Reinforces major concepts and definitions Includes a glossary with a full list of drugs and disorders to support the text
Restoration Ecology. The New Frontier
Enlarged, enhanced and internationalized edition of the first restoration ecology textbook to be published, with foreword by Dr. Steven Whisnant of Texas A&M University and Chair of the Society of Ecological Restoration. Since 2006, when the first edition of this book appeared, major advances have taken place in restoration science and in the practice of ecological restoration. Both are now accepted as key components of the increasingly urgent search for sustainability at global, national, and community levels – hence the phrase 'New Frontier' in the title. While the first edition focused on ecosystems and landscapes in Europe, this new edition covers biomes and contexts all over the world. Several new chapters deal with broad issues such as biological invasions, climate change, and agricultural land abandonment as they relate to restoration science and ecological restoration. Case studies are included from Australia, North America, and the tropics. This is an accessible textbook for senior undergraduate and graduate level students, and early career scientists. The book also provides a solid scientific background for managers, volunteers, and mid-career professionals involved in the practice of ecological restoration. Review of the first edition: «I suspect that this volume will find its way onto the shelves of many restoration researchers and practitioners and will be used as a key text in graduate courses, where it will help fill a large void. My own copy is already heavily bookmarked, and will be a constant source of research ideas and lecture material.» (Environmental Conservation) Companion Website: A companion website with downloadable figures is available at www.wiley.com/go/vanandel/restorationecology
Mathematical Morphology. From Theory to Applications
Mathematical Morphology allows for the analysis and processing of geometrical structures using techniques based on the fields of set theory, lattice theory, topology, and random functions. It is the basis of morphological image processing, and finds applications in fields including digital image processing (DSP), as well as areas for graphs, surface meshes, solids, and other spatial structures. This book presents an up-to-date treatment of mathematical morphology, based on the three pillars that made it an important field of theoretical work and practical application: a solid theoretical foundation, a large body of applications and an efficient implementation. The book is divided into five parts and includes 20 chapters. The five parts are structured as follows: Part I sets out the fundamental aspects of the discipline, starting with a general introduction, followed by two more theory-focused chapters, one addressing its mathematical structure and including an updated formalism, which is the result of several decades of work. Part II extends this formalism to some non-deterministic aspects of the theory, in particular detailing links with other disciplines such as stereology, geostatistics and fuzzy logic. Part III addresses the theory of morphological filtering and segmentation, featuring modern connected approaches, from both theoretical and practical aspects. Part IV features practical aspects of mathematical morphology, in particular how to deal with color and multivariate data, links to discrete geometry and topology, and some algorithmic aspects; without which applications would be impossible. Part V showcases all the previously noted fields of work through a sample of interesting, representative and varied applications.
Professionelles Kundendienstmanagement. Strategie, Prozess, Komponenten
Das Kundendienstmanagement bietet mehr Differenzierungspotenzial gegenuber dem Wettbewerb und gro?ere Wachstumschancen als das reine Produktgeschaft. Die Aufgaben erstrecken sich dabei uber den gesamten Lebenszyklus der Produkte und Leistungen. Dieses Buch stellt ein Modell fur effizientes Kundendienstmanagement vor, das alle kaufmannischen und technischen Kundendienstleistungen erfasst und mehr abdeckt als das klassische After-Sales-Management. Es bietet eine kompakte Einfuhrung in die Thematik, prasentiert einen Managementansatz, der prozessorientiert und logisch aufgebaut ist, und gibt Hinweise, an welchen Stellen des Kundendienstmanagements Optimierungspotenzial besteht. Schwerpunkte der Darstellung sind Handover-Management, Ersatzteilmanagement, Zufriedenheits- bzw. Beschwerdemanagement und Recovery-Management. Auch strategische Fragen, Situationsanalyse, Organisation, Kundenkontakt, Wissensmanagement, Controlling und die kaufmannische Nachbetreuung werden behandelt. – Praktikern dient das Buch als ubersichtliches Nachschlagewerk und Lieferant fur Ideen zur Verbesserung der eigenen Leistungen. – Berufseinsteigern bietet es einen umfassenden Uberblick uber die Zusammenhange, Vorgehensweisen und Methoden. – Studierende fuhrt es in die Aufgabenstellung des Kundendienstmanagements ein und erklart Ihnen Zusammenhange und erfolgsrelevante Stellgro?en.
HIV-1 Integrase. Mechanism and Inhibitor Design
This book comprehensively covers the mechanisms of action and inhibitor design for HIV-1 integrase. It serves as a resource for scientists facing challenging drug design issues and researchers in antiviral drug discovery. Despite numerous review articles and isolated book chapters dealing with HIV-1 integrase, there has not been a single source for those working to devise anti-AIDS drugs against this promising target. But this book fills that gap and offers a valuable introduction to the field for the interdisciplinary scientists who will need to work together to design drugs that target HIV-1 integrase.
Tectonics of Sedimentary Basins. Recent Advances
Investigating the complex interplay between tectonics and sedimentation is a key endeavor in modern earth science. Many of the world's leading researchers in this field have been brought together in this volume to provide concise overviews of the current state of the subject. The plate tectonic revolution of the 1960's provided the framework for detailed models on the structure of orogens and basins, summarized in a 1995 textbook edited by Busby and Ingersoll. Tectonics of Sedimentary Basins: Recent Advances focuses on key topics or areas where the greatest strides forward have been made, while also providing on-line access to the comprehensive 1995 book. Breakthroughs in new techniques are described in Section 1, including detrital zircon geochronology, cosmogenic nuclide dating, magnetostratigraphy, 3-D seismic, and basin modelling. Section 2 presents the new models for rift, post-rift, transtensional and strike slip basin settings. Section 3 addresses the latest ideas in convergent margin tectonics, including the sedimentary record of subduction intiation and subduction, flat-slab subduction, and arc-continent collision; it then moves inboard to forearc basins and intra-arc basins, and ends with a series of papers formed under compessional strain regimes, as well as post-orogenic intramontane basins. Section 4 examines the origin of plate interior basins, and the sedimentary record of supercontinent formation. This book is required reading for any advanced student or professional interested in sedimentology, plate tectonics, or petroleum geoscience. Additional resources for this book can be found at: www.wiley.com/go/busby/sedimentarybasins.
Video Tracking. Theory and Practice
Video Tracking provides a comprehensive treatment of the fundamental aspects of algorithm and application development for the task of estimating, over time, the position of objects of interest seen through cameras. Starting from the general problem definition and a review of existing and emerging video tracking applications, the book discusses popular methods, such as those based on correlation and gradient-descent. Using practical examples, the reader is introduced to the advantages and limitations of deterministic approaches, and is then guided toward more advanced video tracking solutions, such as those based on the Bayes’ recursive framework and on Random Finite Sets. Key features: Discusses the design choices and implementation issues required to turn the underlying mathematical models into a real-world effective tracking systems. Provides block diagrams and simil-code implementation of the algorithms. Reviews methods to evaluate the performance of video trackers – this is identified as a major problem by end-users. The book aims to help researchers and practitioners develop techniques and solutions based on the potential of video tracking applications. The design methodologies discussed throughout the book provide guidelines for developers in the industry working on vision-based applications. The book may also serve as a reference for engineering and computer science graduate students involved in vision, robotics, human-computer interaction, smart environments and virtual reality programmes
Bio-Glasses. An Introduction
This new work is dedicated to glasses and their variants which can be used as biomaterials to repair diseased and damaged tissues. Bio-glasses are superior to other biomaterials in many applications, such as healing bone by signaling stem cells to become bone cells. Key features: First book on biomaterials to focus on bio-glasses Edited by a leading authority on bio-glasses trained by one of its inventors, Dr Larry Hench Supported by the International Commission on Glass (ICG) Authored by members of the ICG Biomedical Glass Committee, with the goal of creating a seamless textbook Written in an accessible style to facilitate rapid absorption of information Covers all types of glasses, their properties and applications, and demonstrates how glass is an attractive improvement to current procedures Of interest to the biomedical as well as the materials science community. The book covers all types of glasses: traditional glasses, bioactive glasses, sol-gel glasses, phosphate glasses, glass-ceramics, composites and hybrids. Alongside discussion on how bio-glasses are made, their properties, and the reasons for their use, the authors also cover their applications in dentistry, bone regeneration and tissue engineering and cancer treatment. Its solid guidance describes the steps needed to take a new material from concept to clinic, covering the essentials of patenting, scale-up, quality assurance and FDA approval.