The surface pigmentation of vertebrates is controlled by specialized cells able to synthesize a variety of pigments collectively known as melanins. Recent research has shown that melanins are produced not only in the skin but also in many other sites such as the eye, inner ear, muscles, etc., – where they are engaged in some unanticipated roles. The details of the synthetic pathway, the complexities of its regulation and biological significance that have been unravelled in recent research comprise a fascinating story and are of key importance in understanding the nature of diseases, including malignant melanoma one of the most rapidly spreading cancers.
Changing Cold Environments; Implications for Global Climate Change is a comprehensive overview of the changing nature of the physical attributes of Canada's cold environments and the implications of these changes to cold environments on a global scale. The book places particular emphasis on the broader environmental science and sustainability issues that are of increasing concern to all cold regions if present global climate trends continue. Clearly structured throughout, the book focuses on those elements of Canada's cold environments that will be most affected by global climate change – namely, the tundra, sub-arctic and boreal forest regions of northern Canada, and the high mid-latitude mountains of western Canada. Implications are considered for similar environments around the world resulting in a timely text suitable for second and third year undergraduates in the environmental or earth sciences courses.
Written by an experienced author with a strong background in applications of this field, this monograph provides a comprehensive and detailed account of the theory behind hydromechanics. He includes numerous appendices with mathematical tools, backed by extensive illustrations. The result is a must-have for all those needing to apply the methods in their research, be it in industry or academia.
This new edition has been extensively revised to reflect the progress in error control coding over the past few years. Over 60% of the material has been completely reworked, and 30% of the material is original. Convolutional, turbo, and low density parity-check (LDPC) coding and polar codes in a unified framework Advanced research-related developments such as spatial coupling A focus on algorithmic and implementation aspects of error control coding
Instructors are under pressure to integrate technology into their traditional or online instruction, but often they aren't sure what to do or why they should do it. The Technology Toolbelt for Teaching offers instructors a down-to-earth guide to common technologies, explains the pedagogical purposes they serve, and shows how they can be used effectively in online or face-to-face classrooms. Designed to be easy to use, the book includes a decision-making matrix for each technology tool: a series of questions that teachers can use to decide whether these tools support their teaching goals. This comprehensive resource contains an array of useful tools that address problems of organization such as a time management calendar, aids for scheduling meetings, and mind-mapping or graphic organizers. The authors also include a variety of online tools for communication and collaboration, and tools to present content, help establish presence, and assess learning. Praise for The Technology Toolbelt for Teaching «Feeling overwhelmed and even afraid of integrating technology into your course? Fear no more! Susan Manning and Kevin Johnson have provided the ultimate guide that explains not only the various technology tools that can support faculty work and enhance coursework but also provides sound advice to help faculty choose the right tool for the job. This is a must-read for all faculty regardless of their experience with technology.»—Rena M. Palloff and Keith Pratt, managing partners, Crossroads Consulting Group, and authors, Building Online Learning Communities and Collaborating Online «The Technology Toolbelt for Teaching delivers exactly what it promises: a concrete overview of a wide variety of tools, complete with examples specific to practitioners in both K–12 and higher education. Authors Susan Manning and Kevin Johnson provide practical applications rather than philosophy, and solutions rather than platitudes. This is a must for any teacher working with—or wanting to start working with—technology.»—Jane Bozarth, author, Social Media for Trainers; eLearning coordinator, State of North Carolina «Creating compelling learning experiences for students is fraught with decision points. Add one or more technology options to the equation, and the number of directions to take learners seems to grow limitlessly, and can either paralyze the instructional design process or cause us to take on too much. Enter The Technology Toolbelt for Teaching. Manning and Johnson's handy guide – and the decision-making matrix that frames each of the tools it demystifies – is an essential resource for choosing paths wisely.»—Jonathan Finkelstein, author, Learning in Real Time; founder and executive producer, LearningTimes Includes 50+ fresh and useful technology tools for teaching A decision matrix for choosing and using the right tools Examples for using each tool in higher education and K–12
This second, comprehensive edition of the pioneering book in this fi eld has been completely revised and extended, now stretching to two volumes. The result is a comprehensive summary of layer-by-layer assembled, truly hybrid nanomaterials and thin fi lms, covering organic, inorganic, colloidal, macromolecular, and biological components, as well as the assembly of nanoscale fi lms derived from them on surfaces. These two volumes are essential for anyone working in the field, as well as scientists and researchers active in materials development, who needs the key knowledge provided herein for linking the field of molecular self-assembly with the bio- and materials sciences.
Marine Geochemistry offers a fully comprehensive and integrated treatment of the chemistry of the oceans, their sediments and biota. The first edition of the book received strong critical acclaim and was described as ‘a standard text for years to come.’ This third edition of Marine Geochemistry has been written at a time when the role of the oceans in the Earth System is becoming increasingly apparent. Following the successful format adopted previously, this new edition treats the oceans as a unified entity, and addresses the question ‘how do the oceans work as a chemical system?’ To address this question, the text has been updated to cover recent advances in our understanding of topics such as the carbon chemistry of the oceans, nutrient cycling and its effect on marine chemistry, the acidification of sea water, and the role of the oceans in climate change. In addition, the importance of shelf seas in oceanic cycles has been re-evaluated in the light of new research. Marine Geochemistry offers both undergraduate and graduate students and research workers an integrated approach to one of the most important reservoirs in the Earth System. Additional resources for this book can be found at: www.wiley.com/go/chester/marinegeochemistry.
The long-awaited revision of the bestseller on heat conduction Heat Conduction, Third Edition is an update of the classic text on heat conduction, replacing some of the coverage of numerical methods with content on micro- and nanoscale heat transfer. With an emphasis on the mathematics and underlying physics, this new edition has considerable depth and analytical rigor, providing a systematic framework for each solution scheme with attention to boundary conditions and energy conservation. Chapter coverage includes: Heat conduction fundamentals Orthogonal functions, boundary value problems, and the Fourier Series The separation of variables in the rectangular coordinate system The separation of variables in the cylindrical coordinate system The separation of variables in the spherical coordinate system Solution of the heat equation for semi-infinite and infinite domains The use of Duhamel's theorem The use of Green's function for solution of heat conduction The use of the Laplace transform One-dimensional composite medium Moving heat source problems Phase-change problems Approximate analytic methods Integral-transform technique Heat conduction in anisotropic solids Introduction to microscale heat conduction In addition, new capstone examples are included in this edition and extensive problems, cases, and examples have been thoroughly updated. A solutions manual is also available. Heat Conduction is appropriate reading for students in mainstream courses of conduction heat transfer, students in mechanical engineering, and engineers in research and design functions throughout industry.
The New Edition of the Well-Regarded Handbook on Gas Chromatography Since the publication of the highly successful first edition of Basic Gas Chromatography, the practice of chromatography has undergone several notable developments. Basic Gas Chromatography, Second Edition covers the latest in the field, giving readers the most up-to-date guide available, while maintaining the first edition's practical, applied approach to the subject and its accessibility to a wide range of readers. The text provides comprehensive coverage of basic topics in the field, such as stationary phases, packed columns and inlets, capillary columns and inlets, detectors, and qualitative and quantitative analysis. At the same time, the coverage also features key additions and updated topics including: Gas chromatography-mass spectrometry (GC-MS) Sampling methods Multidimensional gas chromatography Fast gas chromatography Gas chromatography analysis of nonvolatile compounds Inverse gas chromatography and pyrolysis gas chromatography Along with these new and updated topics, the references, resources, and Web sites in Basic Gas Chromatography have been revised to reflect the state of the field. Concise and fundamental in its coverage, Basic Gas Chromatography, Second Edition remains the standard handbook for everyone from undergraduates studying analytical chemistry to working industrial chemists.
In the current era of complete genome sequencing, Bioinformatics and Molecular Evolution provides an up-to-date and comprehensive introduction to bioinformatics in the context of evolutionary biology. This accessible text: provides a thorough examination of sequence analysis, biological databases, pattern recognition, and applications to genomics, microarrays, and proteomics emphasizes the theoretical and statistical methods used in bioinformatics programs in a way that is accessible to biological science students places bioinformatics in the context of evolutionary biology, including population genetics, molecular evolution, molecular phylogenetics, and their applications features end-of-chapter problems and self-tests to help students synthesize the materials and apply their understanding is accompanied by a dedicated website – www.blackwellpublishing.com/higgs – containing downloadable sequences, links to web resources, answers to self-test questions, and all artwork in downloadable format (artwork also available to instructors on CD-ROM). This important textbook will equip readers with a thorough understanding of the quantitative methods used in the analysis of molecular evolution, and will be essential reading for advanced undergraduates, graduates, and researchers in molecular biology, genetics, genomics, computational biology, and bioinformatics courses.