This book is devoted exclusively to hyper- and hypoparathyroidism with a focus on clinical practice guidelines explained by experts in the field. The clinical, genetic, biochemical, and pharmacological aspects of the most common parathyroid conditions are discussed comprehensively. The 15 chapters review the various forms of hyperparathyroidism and hypoparathyroidism and present data derived from widely diverse sources. New therapeutic approaches for chronic hypoparathyroidism continue to pique interest in parathyroid diseases and show that more research must be done to optimize care. The aim of this book is to serve as a practical guide to clinical management of common parathyroid conditions and to disseminate knowledge useful to the clinic, both for specialists and general practitioners. Also, under- and postgraduates, specialist nurses, and non-experts in the field will find this book to be a valuable source of current information.
As nutrition and development are closely intertwined in early childhood, this book brings together scientists, nutritionists, and psychologists to present a multidisciplinary approach. The first part examines how the biological systems of the body may contribute to healthy growth, looking at bones, muscles, and fat tissues and the optimal nutrition required for dynamic function. The second section contains updates on the latest research on dietary interventions in the areas of growth and body composition, looking at both obesity and stunting worldwide. The final part focuses on neurocognitive development in infancy and early childhood and the role of nutrients in supporting brain growth and function. Highlighting key areas of recent research and potential new fields to explore, this book is of interest for scientists, nutritionists, and psychologists alike.
This comprehensive reference work provides a detailed overview of shockwave therapy, a relatively new clinical specialty in modern medicine. It follows the evolution of Extracorporeal Shockwave Therapy (ESWT) from its initial stage as the gold standard for the disintegration of kidney stones to its regenerative effects in biological tissues. Starting with the basic principles of shockwave treatment, the book goes on to review its application in musculoskeletal disorders, including osteonecrosis of the hip, tendinopathy, fracture treatment, and treatment of sports related injuries. The application of ESWT in cardiovascular diseases is discussed. This includes preclinical and clinical applications for ischemic cardiovascular disease and effects on angiogenesis and anti-inflammation-molecular-cellular signaling pathways. The treatment of urinary diseases and erectile dysfunction by ESWT is elaborated. The book concludes with a discussion of future prospects of the shockwave therapy. Scholars and research fellows interested in shockwave medicine will benefit greatly from this work. It is also a useful clinical resource for nephrologists, urologists, cardiologists, and orthopedists.
Vitamin D deficiency is prevalent today not only among the elderly but pervasively throughout all ages of life.This is due, in part, to systemic diseases that affect vitamin D metabolism, to changes in lifestyle, such as insufficient exposure to sunlight, and to increased use of sunscreen. Apart from the obvious effects of vitamin D deficiency on skeletal metabolism, the problem is assuming even greater significance because observational and interventional studies have linked vitamin D deficiency to cardiovascular disease, cancer, and diabetes. This book addresses a variety of important issues that have emerged from this fast-moving area of clinical medicine. The topics include assays of vitamin D and its binding protein, effects on aging and associated complications, primary and secondary states of altered parathyroid hormone secretion, vitamin D in the growing years of children and adolescents, nutritional requirements, and vitamin D as it relates to systemic disorders such as diabetes mellitus. Vitamin D in Clinical Medicine aims to offer new insights, in an evidence-based way, on important issues related to vitamin D. It is written for general practitioners and internists, as well as for endocrinologists, nutritionists, pulmonologists, cardiologists, and oncologists.
The substantial biological importance of gaseous mediators in various physiological-pathological conditions has been realized only recently, but to date, the detailed mechanisms involved remain elusive. The publication at hand contains 16 overviews written by a panel of experts who summarize the current knowledge and provide fundamental insights into the roles of gaseous molecules in signal transduction in biological systems. The first part provides a comprehensive overview on gaseous mediators in health and disease. In the second part, the medical application of various molecules such as nitric oxide, carbon monoxide, hydrogen sulfide, hydrogen, acetone and phytoncide are discussed. Furthermore, articles on skin gas biology and Carbon-13 (13C), especially clinical applications of 13C-labeled substrate are included. This book provides valuable information not only for basic researchers in physiology and biochemistry, but also for gastroenterologists and clinicians who wish to learn more about the role of gaseous mediators.
Arktis. Et benhardt og iskoldt miljo, hvor dyr og planter gennem artusinder har tilpasset sig ekstreme forhold. Men Arktis er ogsa et sarbart miljo, der i de seneste artier har undergaet store forandringer. Temperaturen er steget markant, og havisen er skrumpet betragteligt. Kan den hojarktiske natur folge med sadanne Aendringer?I denne bog fortAeller 22 danske forskere om mere end 14 ars minutios overvagning af det hojarktiske okosystem i Nordostgronland. Med Forskningsstation Zackenberg som faglig og social ramme har forskerne siden 1995 malrettet arbejdet pa tvAers af videnskabelige fagomrader for at kortlAegge miljoet i en ca. 30 km2 stor dal og forsta klimaets betydning for det samlede okosystem.Historien om naturen og klimaAendringerne i Nordostgronland begynder med historien om etableringen af Forskningsstation Zackenberg og driften af stationen. Herefter folger en rAekke artikler, hvor observationerne bliver fremlagt og forklaret. Hvad sker der med jordmiljoet – med permafrost og kulstofomsAetning? Hvad spirer i plantedAekket og lever i soerne? Og hvordan reagerer trAekfugle, rovdyr og byttedyr, nar fodekAederne Aendrer sig? Dagbogsoptegnelser om forskernes liv og oplevelser fungerer som pauser imellem artiklerne, og bogen afsluttes med et samlet bud pa, hvordan fremtidens Arktis kunne komme til at se ud, hvis den globale opvarmning fortsAetter. Bogen indledes med et forord af Hans Kongelige Hojhed Kronprins Frederik.