Sheila Peters Annie
Список книг автора Sheila Peters AnnieTending the Remnant Damage
Sheila Peters makes her impressive fiction debut with a collection of loosely linked stories whose characters, whether they live in the Queen Charlotte Islands or the Prairies, are ordinary men and women who have seemingly everyday experiences that glimmer with the extraordinary. Her spare, stripped-down prose, leavened with sly humour and a gift for poetic resonance, reminds one of the work of Alice Munro or Sandra Birdsell. Peters creates people who often feel out of sync with the spiritual, emotional, and physical environments they find themselves in. Two old people on a farm try to comprehend the inevitable fate befalling them, all the while contemplating the strange goings-on of neighbours. A young woman on the lam from Texas finds herself beached in the Queen Charlottes on her way to Alaska. A punked-up Vancouver girl accompanies a crusty grandmother on a tense hunting trek in the drizzly woods. Their universe is our universe, but with a twist that makes it refreshingly new and decidedly different.
Physiologically-Based Pharmacokinetic (PBPK) Modeling and Simulations. Principles, Methods, and Applications in the Pharmaceutical Industry
The only book dedicated to physiologically-based pharmacokinetic modeling in pharmaceutical science Physiologically-based pharmacokinetic (PBPK) modeling has become increasingly widespread within the pharmaceutical industry over the last decade, but without one dedicated book that provides the information researchers need to learn these new techniques, its applications are severely limited. Describing the principles, methods, and applications of PBPK modeling as used in pharmaceutics, Physiologically-Based Pharmacokinetic (PBPK) Modeling and Simulations fills this void. Connecting theory with practice, the book explores the incredible potential of PBPK modeling for improving drug discovery and development. Comprised of two parts, the book first provides a detailed and systematic treatment of the principles behind physiological modeling of pharmacokinetic processes, inter-individual variability, and drug interactions for small molecule drugs and biologics. The second part looks in greater detail at the powerful applications of PBPK to drug research. Designed for a wide audience encompassing readers looking for a brief overview of the field as well as those who need more detail, the book includes a range of important learning aids. Featuring end-of-chapter keywords for easy reference—a valuable asset for general or novice readers without a PBPK background—along with an extensive bibliography for those looking for further information, Physiologically- Based Pharmacokinetic (PBPK) Modeling and Simulations is the essential single-volume text on one of the hottest topics in the pharmaceutical sciences today.