Hyperandrogenism in Women. Группа авторов

      Hyperandrogenism in Women

      Frontiers of Hormone Research

      Vol. 53

      Series Editor

      Ezio Ghigo Turin

      Co-Editor

      Federica Guaraldi Turin

      Hyperandrogenism in Women

      Beyond Polycystic Ovary Syndrome

      Volume Editors

      Renato Pasquali Bologna

      Duarte Pignatelli Porto

      24 figures, 12 in color, and 10 tables, 2019

      Frontiers of Hormone Research

      Founded 1972 by Tj.B. van Wimersma Greidanus, Utrecht

      Continued by Ashley B. Grossman, Oxford (1996–2013)

_______________________ Prof. Renato Pasquali, MDEndocrinology and ReproductionUniversity of BolognaBologna (Italy)

_______________________Duarte PignatelliDepartment of BiomedicineFaculty of Medicine of the University of PortoPorto (Portugal)

      Library of Congress Cataloging-in-Publication Data

      Names: Pasquali, Renato, editor. | Pignatelli, Duarte, editor.

      Title: Hyperandrogenism in women : beyond polycystic ovary syndrome / volume editors, Renato Pasquali, Duarte Pignatelli.

      Description: Basel ; New York : Karger, 2019. | Series: Frontiers of hormone research, ISSN 0301-3073 ; vol. 53 | Includes bibliographical references and indexes.

      Identifiers: LCCN 2019000165 (print) | LCCN 2019000859 (ebook) | ISBN 9783318064711 (eBook) | ISBN 9783318064704 (hard cover : alk. paper) | ISBN 978331806471 (e-ISBN)

      Subjects: | MESH: Hyperandrogenism | Adrenocortical Hyperfunction | Women

      Classification: LCC RG207.5 (ebook) | LCC RG207.5 (print) | NLM WK 770 | DDC 618.1--dc23

      LC record available at https://lccn.loc.gov/2019000165

      Bibliographic Indices. This publication is listed in bibliographic services, including Current Contents^® and MEDLINE/Pubmed.

      Disclaimer. The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publisher and the editor(s). The appearance of advertisements in the book is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

      Drug Dosage. The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any change in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.

      All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.

      © Copyright 2019 by S. Karger AG, P.O. Box, CH–4009 Basel (Switzerland)

       www.karger.com

      Printed on acid-free and non-aging paper (ISO 9706)

      ISSN 0301–3073

      eISSN 1662–3762

      ISBN 978–3–318–06470–4

      e-ISBN 978–3–318–06471–1

      Contents

Foreword

      Pasquali, R. (Bologna); Pignatelli, D. (Porto)

In utero Androgen Excess: A Developmental Commonality Preceding Polycystic Ovary Syndrome?

      Abbott, D.H.; Kraynak, M. (Madison, WI); Dumesic, D.A. (Los Angeles, CA); Levine, J.E. (Madison, WI)

Androgens, Body Composition, and Their Metabolism Based on Sex

      Giagulli, V.A.; Castellana, M. (Bari); Pelusi, C. (Bologna); Triggiani, V. (Bari)

       Understanding the Role of Androgen Action in Female Adipose Tissue

      Schiffer, L.; Arlt, W.; O’Reilly, M.W. (Birmingham)

       The Role of Androgen Excess on Insulin Sensitivity in Women

      Diamanti-Kandarakis, E.; Pappalou, O.; Kandaraki, E.A. (Athens)

       Androgens in Congenital Adrenal Hyperplasia

      Pignatelli, D.; Pereira, S.S. (Porto); Pasquali, R. (Bologna)

       Androgens in Cushing’s Syndrome

      Arnaldi, G.; Martino, M. (Ancona)

       Hyperandrogenism and Adrenocortical Tumors

      Di Dalmazi, G. (Bologna)

       Androgen-Secreting Ovarian Tumors

      Macut, D.; Ilić, D.; Mitrović Jovanović, A.; Bjekić-Macut, J. (Belgrade)

       Endocrinology of Hirsutism: From Androgens to Androgen Excess Disorders

      Yilmaz, B. (Izmir); Yildiz, B.O. (Ankara)

       Obesity and Androgens in Women

      Pasquali, R.; Oriolo, C. (Bologna)

       Androgens in Menopausal Women: Not Only Polycystic Ovary Syndrome

      Kostakis, E.K.; Gkioni, L.N. (Athens); Macut, D. (Belgrade); Mastorakos, G. (Athens)

       Androgen Excess in Women: Proteomic and Metabolomic Approaches

      Insenser, M.; Escobar-Morreale, H.F. (Madrid)

       Androgens and Severe Insulin Resistance States: Basic and Clinical Aspects

      Gambineri, A.; Zanotti,