Provides synthetic chemists with a method for rapid retrieval of information from the literature, listing material by reaction type rather than by author name or publication date. Each updated volume presents the latest synthetic methods for preparation of monofunctional and difunctional compounds. The organization is logical and easy to follow; sections are arranged according to the possible interconversions between the major functional groups. Enables synthetic chemists to keep abreast of recent developments and retrieve a specific piece of information quickly and easily.
This book is an account of current developments in computational chemistry, a new multidisciplinary area of research. Experts in computational chemistry, the editors use and develop techniques for computer-assisted molecular design. The core of the text itself deals with techniques for computer-assisted molecular design. The book is suitable for both beginners and experts. In addition, protocols and software for molecular recognition and the relationship between structure and biological activity of drug molecules are discussed in detail. Each chapter includes a mini-tutorial, as well as discussion of advanced topics. Special Feature: The appendix to this book contains an extensive list of available software for molecular modeling.
A compilation of recent advances and applications in asymmetric catalysis The field of asymmetric catalysis has grown rapidly and plays a key role in drug discovery and pharmaceuticals. New Frontiers in Asymmetric Catalysis gives readers a fundamental understanding of the concepts and applications of asymmetric catalysis reactions and discusses the latest developments and findings. With contributions from preeminent scientists in their respective fields, it covers: * «Rational» ligand design, which is critically dependent on the reaction type (reduction, oxidation, and C-C bond formation) * Recent findings on activation of C-H bonds, C-C bonds, and small molecules (C=O, HCN, RN=C, and CO2) and the latest developments on C-C bond reorganization, such as metathesis * Advances in «chirally economical» non-linear phenomena, racemic catalysis, and autocatalysis * Some of the recent discoveries that have led to a renaissance in the field of organocatalysis, including the development of chiral Brönstead acids and Lewis acidic metals bearing the conjugate base of the Brönstead acids as the ligands and the chiral bi-functional acid/base catalysts The book ends with a thought-provoking perspective on the future of asymmetric catalysis that addresses both the challenges and the unlimited potential in this burgeoning field. This is an authoritative, up-to-date reference for organic chemists in academia, government, and industries, including pharmaceuticals, biotech, fine chemicals, polymers, and agriculture. It is also an excellent textbook for graduate students studying advanced organic chemistry or chemical synthesis.
Fractals, Diffusion and Relaxation in Disordered Complex Systems is a special guest-edited, two-part volume of Advances in Chemical Physics that continues to report recent advances with significant, up-to-date chapters by internationally recognized researchers.
A new volume in the «Perspectives in Supramolecular Chemistry» series focusing on separating supramolecular structures, a key step in supramolecular chemistry. Two guest editors have been at the forefront of the development of chromatographical methods to deal with supramolecular systems. Reactions of supramolecular structures show the way into the future of chemistry. Fumio Toda is one of the driving forces in the development of supramolecular separation systems. A practical title in the prestigious “Perspectives in Supramolecular Chemistry” series.
Defects play an important role in determining the properties of solids. This book provides an introduction to chemical bond, phonons, and thermodynamics; treatment of point defect formation and reaction, equilibria, mechanisms, and kinetics; kinetics chapters on solid state processes; and electrochemical techniques and applications. Offers a coherent description of fundamental defect chemistry and the most common applications. Up-to-date trends and developments within this field. Combines electrochemical concepts with aspects of semiconductor physics.
This scientifically sound, yet easily readable book provides the fundamentals necessary to understand today's energy and climate problems and provides possible answers based on current technology such as solar, water and geothermal power. Moreover, it introduces the reader to new concepts that are already or may soon be realized, such as nuclear fusion or a hydrogen-based economy. Aimed at a wide readership ranging from educated laypeople and students to practitioners in engineering and environmental science.
Auch beim Thema Altlasten setzen praktische Problemlosungen das Verstandnis der grundlegenden chemischen und biologischen Prozesse voraus. Zu diesem Verstandnis verhilft das vorliegende Buch. Erstmals nehmen Experten darin auch zur okotoxikologischen Bewertung von Altlasten Stellung. Das Buch ist entsprechend der praktischen Vorgehensweise gegliedert. Es beginnt mit der Probenahme, geht uber die Analytik bis hin zu Sanierungsma?nahmen. Mit Altlasten konfrontierte Naturwissenschaftler und Ingenieure konnen sich mit diesem Werk praktisches Know-how verschaffen. Es dokumentiert die Ergebnisse eines Arbeitskreises der Fachgruppe Wasserchemie in der GDCh und zeugt dadurch von gro?er Erfahrung und Praxisrelevanz.
Im Rahmen der internationalen Verhandlungen uber Persistent Organic Pollutants (POPs) und in der EU wie auch in einzelnen Mitgliedsstaaten werden zur Zeit neue Ansatze zur Chemikalienbewertung diskutiert. Der Autor schlagt dazu in diesem Buch ein neuartiges Konzept vor, das auf Persistenz und Reichweite der Chemikalien beruht. Er geht dabei von der Annahme aus, da? die Trennung von Beschreibung und Bewertung in den Umweltwissenschaften unangemessen ist, wenn von diesen Wissenschaften erwartet wird, da? sie aussagekraftige Bewertungsverfahren liefern: Bewertungen sind keine rein naturwissenschaftliche Aufgabe, sondern erfordern einen Bezug zu rechtlichen, okonomischen oder ethischen Kriterien. Das vorliegende Buch stellt eine Verbindung zwischen ethischen Bewertungskriterien und den naturwissenschaftlichen Indikatoren Persistenz und Reichweite her und liefert damit einen Beitrag zur Frage, wie das Postulat der Nachhaltigkeit im Bereich der Umweltchemikalien konkretisiert werden kann. Auf dieser Grundlage werden Vorschlage entwickelt, wie die Chemikalienbewertung vereinfacht werden kann, ohne da? auf eine aussagekraftige Stoffbeurteilung verzichtet werden mu?.
This first comprehensive book to cover this exciting field also deals with the biological aspects, such as enzymes with iron. Following an introduction, this handy reference and handbook goes on to deal with reductions, oxidations of C, H- and C=C bonds, oxidative allylic oxygenation and amination, the oxidation of heteroatoms, cross coupling reactions, aromatic and nucleophilic substitutions, addition to carbonyl compounds, and cyclisations as well as ring opening reactions. The chapters are clearly classified according to the reaction type, allowing readers to quickly locate the desired information.