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Список книг автора Группа авторовHPLC Methods for Recently Approved Pharmaceuticals
An indispensable resource for busy researchers Your time is valuable-too valuable to spend hunting through the technical literature in search of the right HPLC assay techniques for your projects. With HPLC Methods for Recently Approved Pharmaceuticals, you'll quickly identify and replicate the ideal procedures for your project needs, without having to refer to original source publications. More of your time can then be spent in the lab, not the library. Covering the relevant world literature through 2003, this book picks up where Dr. Lunn's acclaimed HPLC Methods for Pharmaceutical Analysis left off. It arms you with established HPLC assay techniques for hundreds of newly approved drugs, as well as drugs for which assay methods were only recently developed. Combining detailed descriptions of procedures with specially annotated references, this practical handbook gives you: * HPLC methods for 390 commonly prescribed pharmaceutical compounds * Various procedures for each drug listed together-making it easy to mix and match for customized approaches * Methods for drugs in biological fluids and for bulk and formulated drugs * Chemical structures, molecular weights and formulas, and CAS Registry Numbers * Cross-references to The Merck Index * Retention times of other drugs that can be assayed using the same methods
Principles and Practice of Variable Pressure
Offers a simple starting point to VPSEM, especially for new users, technicians and students containing clear, concise explanations Crucially, the principles and applications outlined in this book are completely generic: i.e. applicable to all types of VPSEM, irrespective of manufacturer. Information presented will enable reader to turn principles into practice Published in association with the Royal Microscopical Society (RMS) -www.rms.org.uk
Raman Spectroscopy for Soft Matter Applications
Raman spectroscopy provides a critical characterization tool in analytical chemistry. This book presents the fundamentals of raman spectroscopy outside the focus of physics to offer an accessible guide to scientists working in the broad area of soft materials. The book is organized into four sections with the first devoted to an introduction to Raman spectroscopy which includes scattering theory and instrumentation. The following sections are devoted to application areas including polymers and colloids, food science, drug delivery, defense, and medical.
Forensic Analysis on the Cutting Edge
This title brings forensic scientists and chemists up-to-date on the latest instrumental methods for analysing trace evidence, including mass spectrometry, image analysis, DIOS-MS, ELISA characterization, statistical validation, and others. Illustrates comparative analysis of trace evidence by both old and new methods. Explains why some newer methods are superior to older, established methods. Includes chapters on analysis of DNA, ink, dyes, glitter, gun powder traces, condom trace evidence, footwear impressions, toolmark impressions, surveillance videos, glass particles, and dirt. Discusses applications such as mass spectrometry, image analysis, desorption-ionization on silicon mass spectrometry (DIOS-MS), ELISA characterization, and statistical validation.
On Chirality and the Universal Asymmetry
Until half a century ago, it was assumed that the forces of nature were symmetric and that they did not distinguish between right and left, between image and mirror image. The discovery of the violation of parity in 1956 was more than a sensation, for some it was a shock. It implied that the universe displays handedness, or chirality, and that it is fundamentally asymmetric. Remarkably, a most striking asymmetry is encountered in the realm of biology. Living organisms contain proteins built almost exclusively from L-amino acids, and nucleic acids derived from D-sugars only. Yet a mirror-image biochemistry, based on D-amino acids and L-sugars is, from a purely chemical standpoint, entirely conceivable. Where, then, does this extraordinary natural selectivity come from? Is it directly, or indirectly, connected to the universal violation of parity? This book is meant as a brief review of the various manifestations of handedness, or chirality, in the universe. It does not attempt to present a solution to basic questions which perhaps will never be unambiguously and conclusively answered. Rather, it is an excursion through nature, to observe and recognize how the chirality manifests itself at different structural levels. The excursion starts in the chemistry and physics laboratory. Then a journey into outer space and back in time is undertaken. After a return to our planet Earth, the focus is on the development of living organisms. The text should be accessible to anyone having the equivalent of a first-year university instruction in physics and chemistry. It is also hoped that a layperson with a more modest scientific formation may gain a general impression of the basic asymmetry in nature and of the fundamental significance of chirality. Mathematical expressions, wherever they occur, may then be overlooked. Some more difficult sections may be skipped. A Glossary preceding the Subject Index should be helpful.
Chemische Experimente in naturwissenschaftlich-technischen Museen
Georg Schwedt ladt Sie ein, ihn auf seiner abwechslungsreichen Reise durch ausgewahlte naturwissenschaftlich-technische Museen quer durch Deutschland zu begleiten. Die Stationen seiner spannenden Reise sind: ? das Bergbaumuseum Weltkulturerbe Rammelsberg Goslar, ? das Deutsche Erdolmuseum Wietze, ? das Deutsche Salzmuseum Luneburg, ? das Deutsche Apothekenmuseum Heidelberg, ? das Landesmuseum fur Technik und Arbeit Mannheim, ? das Museum fur Brotkultur Ulm und ? das Fuhlrott-Museum & Forschungsinstitut in Wuppertal. In bewahrter Manier kombiniert Georg Schwedt spannende Chemieexperimente mit interessanten Hintergrundinformationen zu den Museen und ihren vielfaltigen Themenschwerpunkten. Lassen Sie sich einfangen von der Faszination, wie man mit einfachen Hilfsmitteln Chemieexperimente – ob im Museum, in der Schule oder zu Hause – nachvollziehen kann. Wie kann beispielweise aus dem Grundstoff Erdol ein Arzneimittel hergestellt werden? Wie entsteht lockeres Brot aus den Grundzutaten Mehl, Backtriebmittel und Wasser? Und vielleicht konnen die Experimente Sie so fesseln, dass Sie als nachste Urlaubsreise eine Museumstour planen, um die vorgestellten Museen einmal in Natura kennen zu lernen. Oder Sie nutzen den nachsten anstehenden Schulausflug, um den falschlich als langweilig verponten Museumsbesuch bei Jugendlichen und Schulern zu einem attraktivem Erlebnis zu machen. Dieses Buch ist fur alle Kenner der anderen «Schwedt Experimentierbucher», fur naturwissenschaftlich interessierte Kulturhistoriker, fur kulturhistorisch interessierte Naturwissenschaftler und naturlich fur alle, die einfach gerne ins Museum gehen und dort mehr wollen als nur Exponate ansehen.
Polymeric Materials in Organic Synthesis and Catalysis
This is the first book to describe the synthesis and characterization of the materials used in polymer-supported synthesis. The authors cover not only the classical polymers and their use in homogeneous, heterogeneous and micellar catalysis, but also such new developments as «enzyme-labile linkers», illustrating how to simplify the purification process and avoid waste. The result is a wealth of useful information – for beginners and experts alike – in one handy reference, removing the need for difficult and time-consuming research among the literature.
Solvents and Solvent Effects in Organic Chemistry
In most cases, every chemist must deal with solvent effects, whether voluntarily or otherwise. Since its publication, this has been the standard reference on all topics related to solvents and solvent effects in organic chemistry. Christian Reichardt provides reliable information on the subject, allowing chemists to understand and effectively use these phenomena. ? 3rd updated and enlarged edition of a classic . 35% more contents ? excellent, proven concept ? includes current developments, such as ionic liquids ? indispensable in research and industry From the reviews of the second edition: «…This is an immensely useful book, and the source that I would turn to first when seeking virtually any information about solvent effects.» – Organometallics
Bioavailability, Bioaccessibility and Mobility of Environmental Contaminants
This book covers all aspects of bioavailability, as related to environmental contaminants. After a discussion of the definition of bioavailability and its context, focus is placed on the role of risk assessment and bioavailability. Methods of analysis are then discussed including a range of atomic spectroscopic and electrochemical techniques for metal analysis and chromatographic approaches for persistent organic pollutants (POPs). The occurrence, properties and eco-toxicity of POPs and metals in the soil/sediment environment are discussed. Particular emphasis is placed on the uptake of POPs and metals by plants (phytoextraction). Examples of POPs and metals in the environment are reviewed. Methods to assess the bioavailability of POPs and metals in the environment are discussed. The particular approaches considered are: non-exhaustive extraction techniques single extraction techniques sequential extraction techniques use of cyclodextrin and surfactants in-vitro gastrointestinal methods including physiological-based extraction test the use of bioasssays including earthworms. Finally, selected case studies highlight the importance of determining the bioavailability of POPs and metals.
Six-Membered Transition States in Organic Synthesis
This book furthers readers’ understanding of the amazing features of six-membered transition states in stereoselective organic reactions. Comprehensive and logically organized, it covers reactions classified in four categories: [3,3]-sigmatropic rearrangements, aldol reactions, metal allylation reactions, and stereoselective reductions. There is a thorough discussion of each reaction category, along with computational studies that support a proposal of a six-membered state. The book assists professors, researchers, and students in proposing reasonable transition states for the description of newly discovered stereoselective reactions.